C. Kusiya Utachiwana Zvakaoma Kupararira
Clostridium difficile ( C. yakasiyana ) inokonzera zvirwere zvezvirwere zvebhakitiriya mumakoroni. Iwe unogona kunge uine mabhakitiriya, asi hauna zviratidzo. Kana, iwe unogona kuona zviratidzo kubva pahutachiita hunyoro kusvika kune zvakanyanya kuoma, dzimwe nguva kutyisidzira kurwara (kupisa kwekoni).
Vanhu vazhinji vanotapukirwa neClostridium difficile havazorwere.
Zvisinei, zvakakosha kuyeuka kuti iwe unogona kuparadzira chirwere chisingazivi. Vanhu vanogona kurwara ndevaya vari muchipatara kana kutora mishonga inorwisa mabhakitiriya.
Iyo inopararira sei: Chirwere ichi chinoitika apo mumwe munhu ave achitora mishonga inorwisa mabhakitiriya kana ane humwe hutachiona hunotapukirwa nebhakitiriya. Izvi zvinowanzoitika pavanoshandura mabhakitiriya kubva pane zvakasvibiswa-zvinhu zvakasvibiswa kana zvisikwa kumuromo wavo kana mumhino.
Clostridium difficile inobata mishonga inogona kuumba spores inopona mumhepo kwemwedzi. Muzvirongwa zvechipatara, spores inopararira kubva kurwere-kusvika kune murwere, uyewo kubva kuvashandi vezvipatara kuti vatsungirire.
Iyo inokonzera chirwere: Kurapa kwezvirwere zvebhakitiriya nemishonga inorwisa mabhakitiriya inogona kuuraya pamwe chete mabhakitiriya anogara, anonziwo "microflora," anogara mucoloni yako. Iyo microflora inowanzochengetedza mbeu yako, asi iyo isipo, zvimwe zvirwere zvinotapukira, zvakadai seClostridium difficile (iyo inonyanya kusagadzikana nemishonga inorwisa mabhakitiriya yakawanda) inogona kutora nzvimbo yayo uye inokonzera zvirwere.
Clostridium difficile inobereka uturu hunokonzera kurara nemasero anokuvadza ari mumakoloni, zvichiita kuti zvive zvezvironda (maronda) mumutumbi. Izvozvo zvinokonzera kukuvadza kwakanyanya, uye masvikiro akafa anokonzera uye simbi anogona kuita "pseudomembrane," iyo inofanirwa nehosha.
Muna 2006, chigadzirwa chitsva cheClostridium difficile chinonzi NAP1, icho chinowedzera ka20 zvakanyanyisa chepfu kune mamwe matambudziko, akawanikwa achiita zvirwere zvezvironi zvekuwedzera kwakanyanya nekufa.
MunaNovember 2008, dambudziko reNAP1 rinogona kunge rakafa rakaratidzwa kuti rinosvika makumi maviri rinopfuura rakawanda kupfuura raimbofunga. (Dambudziko racho ringangodaro rinokonzera kuputika kubva muna 2000.)
Ndiani ari pangozi? Vanhu vose vanogona kutapukirwa, asi vanhu vari kutora mishonga inorwisa mabhakitiriya kana kuti vari muchipatara vari pangozi yekuwana zvirwere zvakakomba. Zvimwe zvinhu zvinowedzera njodzi yezvirwere zveClostridium difficile dzinosanganisira nguva refu yekugara muchipatara, makore anopfuura makumi matanhatu, chirwere chakakomba, nekugara munzvimbo dzekuchengetedza kwenguva refu. Vacheche vashoma vanogona kuwana zvirwere nekuti havakanganisi neClostridium difficile inxin.
Zviratidzo uye Zviratidzo: Chiratidzo chekutanga chirwere chemvura, katatu kana kupfuura pane zuva kwemazuva maviri. Zvimwe zviratidzo zvinosanganisira fivha, kuora mwoyo, kurasikirwa kwechido, uye kurwadziwa mumimba .
Kuongororwa: Kuongorora kwakasiyana-siyana kunowanikwa kuClostridium difficile , kusanganisira avo vanoona tsvina yakananga muzvidzidzo zvezvigaro uye tsika dzebhakitiriya nokuda kwemakemikari. Ikoko huru inopinda muchena machena kuverenga inogonawo kuva chiratidzo.
Kurapa: Kushandisa kwezuva gumi kwemishonga inorwisa mabhakitiriya, yakadai semuromo vancomycin kana metronidazole, inokurudzirwa. Zvisinei, sezvo utachiona hunogona kukonzerwa nokushandiswa kweumwe mushonga unorwisa mabhakitiriya munzvimbo yekutanga, mumwe angada kumira pamishonga yakatemwa kwenguva refu.
Kurapa kunovimbiswa kunovimbiswa , kunonzi fecal bacteriotherapy , kunosanganisira kutora fecal zvinhu kubva kune munhu anopa utano kuti achinje kusawirirana kwebhakitiriya mumatumbo. Iyo microbiome ine utano yakangodaro yakabviswa nemishonga inorwisa mabhakitiriya uye saizvozvo C Diff inogona kubudirira; kuisa fecal kunoita kuti microbiome itsva idyarwa.
Zvirwere uye Zvinetso: Vanhu vazhinji vanowana chirwere cheClostridium difficile vachave nekurwara kwemahara. Chirwere chakakomba, chakadai sekoriti, chinogona kuitika uye chinoda kurapwa. Pasina kurapa, chirwere chinogona kuwedzera kuva zvirwere zvakakomba, zvakadai se fulminant colitis, inoda kubvunzurudzwa nokukurumidza.
Kudzivirira: Nemhaka yokuti chirwere cheClostridium difficile chinonyanya kuitika mushure mekushandisa maantibiotic, zvinokosha kudzivisa kushandiswa kwemishonga inorwisa mabhakitiriya mukurapa zvirwere zvavanoda. Mukuwedzera, kushamba maoko nguva dzose uye kusvibiswa kwemazingira kunofanira kuitwa. Doro-based based disinfection haina kubvisa C. diff spores, saka kushamba maoko kunonyanya kukosha.
Sources:
Zvose Zvakajeka pamusoro peClostridium difficile Infections. Nzvimbo dzeDaase Control uye Kudzivirira.
National US Inpatient Healthcare Facility Clostridium difficile Survey. . APIC Research Foundation.
Salyers AA uye Whitt DD. Bhakteria Pathogenesis: Nzira yeMatomu. © 1994, American Society for Microbiology, Washington, DC. pp. 282-289.
Sunenshine RH uye McDonald LC. Clostridium difficile- chirwere chakabatanidzwa: Mitsva mitsva kubva pathogen yakagadzirwa. Cleveland Clinic Journal of Medicine. 2006; 73: 187.