Mubvunzo unowanzobvunzwa nevanhu vane nhoroondo yepenicillin allergies ndeyekuti vanogona kutora cephalosporin. Ichi ndechokuti penicillin uye cephalosporin ma antibiotics anovakwa zvakafanana kune mumwe.
Usati wapindura mubvunzo uyu, zvakadaro, zvakakosha kutanga kutarisa kana kana munhu asiri yeaergic penicillin-chinhu chisingazivikanwi chisingaiti chinogona kukanganisa kutarisira kwako.
Penicillin: Beta-Lactam Antibiotic
Penicillin ndiyo inonyanya kuzivikanwa nhengo yeboka remishonga inorwisa mabhakitiriya rinonzi beta-lactam. Mishonga yose ye beta-lactam ine chimiro chairo (chinonzi bheta-lactam ring) mukati mekudzikisa kwema molecular.
Kunze kwepenicillin, mamwe beta-lactam anosanganisira:
- Penicillin derivatives like amoxicillin
- Cephalosporins saKeflex (cephalexin)
- Carbapenems sa Primaxin (imipenem)
Penicillin Allergy: An IgE-mediated Response
Izvo zvinowanzoitika zvinogadziriswa ne penicillin ndeyeIg-mediated (Type 1) hypersensitivity response. Izvi zvinoreva kuti kana paine pepa penicillin, zvirwere zvemuviri zvevanhu (kana allergic) zvichaita zvirwere zveGGE. Izvo zvinorwisa zvirwere zvinofamba uye zvinosunga kune mamwe masero mukati memuviri womunhu, zvichiita kuti vasunungure makemikari. Aya makemikari ndeapi anokonzera zviratidzo zveanoripika.
Zviratidzo uye zviratidzo zvepenicillin zvirwere zvinowanzotanga mukati memaminitsi kusvika paawa kana maviri kutora mishonga uye inogona kusanganisira chimwe kana zvimwe zvinotevera:
- Ganda Itching uye / kana mikoko
- Itching kana kurira kwemiromo kana rurimi
- Angioedema (kurira kwemuromo, maziso, miromo, kana rurimi)
- Kugurisa uye kupera kwekufema
- Dambudziko kukumedza
- Low blood pressure
- Lightheadedness
- Kutsanya mwoyo kutsva
Sei Kutarisa Kwechokwadi Penicillin Kurwisa Kwese Kunokosha?
Maererano neCenters for Disease Control and Prevention , vanenge 10 kubva muzana vevanhu vose veAmerica vanorondedzera kukanganisa kwepenicillin-class antibiotic, asi pasi pepfumbamwe muzana inonyanya kurwisa (inobva pakucheneswa kweganda).
Zvichida, ivo vakanganisa zvakanyorwa se penicillin inoratidzira muchechi yavo kana kuti zvirwere zvadzo zvakagadziriswa nenguva-inenge 80 muzana yevanhu vane penicillin allergies vanorasikirwa ne hypersensitivity mushure memakore gumi (kureva kuti haisi yega yega).
Sezvo vanhu vakawanda vanofunga kuti vane allergenic penicillin havakwanisi, zvakakosha kuti iwe nachiremba wako muve nechokuita kuti pfungwa iyi isakanganisika. Izvi ndezvokuti mishonga yakawanda inorwisa mabhakitiriya inowanzopiwa seimwe nzira yepenicillin.
Dhiyabhorosi yakakura-inorwisa mabhakitiriya inogona kuwedzera mungozi yako yekurwisa mabhakitiriya mune ramangwana uye inowanzova inodhura. Uyewo, mushonga unorwisa mabhakitiriya unorayirwa nachiremba wako haufaniri kuva wakanakisisa kune utachiona hwako.
Kugutsikana nePenicillin Allergy: Kucheka Kweputi Ndiyo Gold Standard
Kuti uone kana iwe usina penicillin zvinorega here kana kuti kwete, chiremba wako achatora mishonga yezvinodhaka zvenhoroondo uye kubva pane iyo ruzivo rucherechedza kana penicillin kuongorora kweganda (izvo zvinoda kuendeswa kwezvirwere) zvinoda.
Semuenzaniso, zvichida iwe wakagadzira kushushikana kana chirwere chemupiriso paunopedza kupora penicillin. Ichi hachisi chokwadi chechokwadi, asi panzvimbo yegeallergic side effect.
Kana kuti iwe hauna kumbobvira watora penicillin asi iwe une nhengo yemhuri ine penicillin inorwara.
Izvi, zvekare, hazvirevi kurwisa pane iwe. Muzviitiko izvi, chiremba wako angangoenda mberi uye kurapa utachiona hwako ne penicillin kana cephalosporin (kana zvichibvira).
Paflip side, kana usina chokwadi nezvepakutanga kwako kupenicillin, kana kana iwe chiremba usingagutsikani kana kupindura kwacho kwaiva kweanorikisi kana kuti kwete, kuongororwa neanoripoteri kunofanira kuitwa.
Kudzivirirwa Kwekutora Cephalosporin Ne Penicillin Allergy
Ngatiti iwe unoona anoristorist, uye ruvara rweganda rako rakanaka kune penicillin allergy. Muchiitiko ichi, iwe unofanirwa kudzivisa zvose penicillin.
Zvisinei, iwe unogona kunge uchikwanisa kutora cephalosporin pasi pehutungamiri hwepedyo weer allergist yako.
Izvi ndezvokuti chete boka duku revanhu (anenge anenge 3 muzana) ne penicillin zvirwere zvese zvichaita kune cephalosporin-zvisinei, kupindura kunogona kuoma.
Mhando ye cephalosporin iwe uri kutora ichakurukurwa zvakare. Izvi ndezvokuti apo kutsvakurudza kunoratidza dambudziko rakanyanya rekuita kune cephalosporin kune vanhu vane penicillin noutachiona, kune imwe chete-yekutanga-cephalosporins dzinonzi cephalexin (Keflex) uye cefazolin (Ancef) inokonzera kuwedzera kwehutano hwehupenyu hwevanhu vane penicillin allergies kupfuura vanhu vasina penicillin allergy.
Paflip side, yechipiri uye chechitatu chizvarwa cephalosporins, chakadai se cefuroxime (Ceftin), cefprozil (Cefzil), cefdinir (Omnicef), uye cefpodoxime (Vantin), haisi kuita kuti zvirwere zvinowedzera zvirwere kuvanhu vane penicillin .
Shoko Rinobva
Chinonyanya kukosha ndechokuti apo vanhu vazhinji vane nhoroondo ye penicillin zvirwere zvinogona kushivirira cephalosporins, vanachiremba vakawanda vanoshandisa kuchenjerera pavanorondedzera imwe, sezvinoitika zvinogona kuva zvakanyanya.
Mukuwedzera, zvakakosha kunzwisisa kuti pane zvakawanda zvinobatanidzwa muchisarudzo chekupa cephalosporin, sechirwere chetachiona chinoda kurapwa uye chakakodzera / kuwanika kwekusina penicillin / kwete-cephalosporin antibiotics inogona kushandiswa.
> Sources:
> Blumenthal KG, Shenoy ES, Hurwitz S, Varughese CA, Hooper DC, Banerji A. Migumisiro yezvinodhaka zvemishonga yezvirwere zvemishonga uye antibiotic inorondedzera murayiridzo kune varwere vepachipatara vanopa mishonga inorwisa mishonga inorondedzera zivo. J Allergy Clin Immunol Pract . 2014 Jul-Aug; 2 (4): 407-13.
> Blumenthal KG, Solensky R, Kurwisa kwemarudzi ose kuongororwa kwekurumidza penicillin zveruzhinji: Ganda rekuongorora-based based diagnostic strategies uye cross-reactivity nedzimwe beta-lactam antibiotics.
> D ePestel DD et al. Cephalosporin inoshandiswa mukurapa varwere vane penicillin miviri. J Am Pharm Assoc (2003). 2008 Jul-Aug; 48 (4): 530-40.