Chii chinonzi monoclonal antibody? Ko monoclonal antibodies inoshanda sei kurapwa kwerheumatoid arthritis? Ndeupi wezvinonzi biologic zvinodhaka zvinoshandiswa nemaoko masimba? Vari kunyanya mukubudirira here?
Zvirwere zvepamuviri ndizvo mapuroteni anokonzerwa nemasikirwo emusikirwo, kunyanya masero eropa. Vanopararira muropa uye vanobatanidza kune mapuroteni ekunze anonzi antitigens kuitira kuti vaparadze kana kuti varege kuvadzivisa.
Semuenzaniso, kana iwe uine hutachiona, muviri wako unobereka zvirwere zvekudzivirira kuti ubvise urongwa hwako hwehutachiona.
Mishonga Inowanikwa
Monoclonal antibodies inobatori-yakagadzirwa zvinhu zvinogona kuwana uye kusunga kune mamwe malekoro, akadai se tumor necrosis factor (TNF) , puroteni inobatanidzwa mukukonzera kuputika nekukuvara kwerheumatoid arthritis . Zvimwe zveNANF inhibitor ndezvinyorwa zveprotein.
- Remicade, iyo inoshandiswa nekuputika kwepachivande, inoshandisa kusanganiswa kwevanhu uye mapuroteni emapurogiramu ekuumba puroteni yakasvibiswa inozivikanwa se chimeric monoclonal antibody.
- Humira, iyo inoshandiswa nejojo, inobudiswa kubva kumapuroteni evanhu.
- Simponi munhu anonzi monoclonal antibody. Inowanikwa sejisi kana kuputika.
Kubudisa mapuroteni anogadzirwa nevanhu inzira inoshamisa inosanganisira kuisa masero muzvigadzirwa zvisingasviki zvidhina zvisina kuvharwa zvine utachiona kuti zvive neprotein yakataurwa.
Inonyanya kuongororwa kuti ione kuti yakachena isati yagadzirira kushandiswa kwevarwere.
Imwe puroteni ye monoclonal inogamuchirwa kuti kurapwa kwerheumatoid arthritis iRituxan. Kufanana Remicade, iyo is chimeric mouse / munhu monoclonal antibody iyo inopiwa nehuputi hwekudzivirira. Kusiyana neRicicade, inorwisa mabero eB asipikisa TNF.
Miti mishomanana mitsva inokonzerwa ne-monoclonal iri muchitamba chekusimudzira kurapa rheumatoid arthritis nezvimwe zvinhu.
Dr. Zashin ndiye kliniki mudzidzisi wechipatimendi paYunivhesiti yeTexas Southwestern Medical School uye chiremba anoenda kuPresbyterian Hospitals ye Dallas uye Plano. Dhiyabhorosi Zashin munyori weArthritis Pasina Pain - Chishamiso cheNADF Blockers uye mubati wenhengo yeAtmal Arthritis Treatment .