Antithyroid Zvinodhaka Zvinoshandiswa Kuita Matombo 'Denda uye Hyperthyroidism
Antithyroid mishonga - inonziwo thioamide - ndiyo mishonga inorapa utachiona husingaitiki (hyperthyroidism) nekudzivirira utachiona hwekodzero yekubudisa hormone yekemikari. Mukurapa kwehutachiona hunopedza simba, iyo inonyanya kuguma kubva mumamiriro ekudzivirira anozivikanwa seGraves 'chirwere, zvakakosha kuderedza kushandiswa kwakanyanya kweglande emakironi ematokisi, kunyanya mahomoni thyroxine (T4) uye triiodothyronine (T3).
Anodithyroid mishonga inoshanda nekuita kuti zvive zvakaoma kuti muviri ushandise iodine, nokudaro kudzivisa kuumbwa kwehomoni yekemikari mune gland.
Antithyroid drug therapy ndeimwe yemishonga ye hyperthyroidism neGreat 'disease. Mimwe mishonga inosanganisira iodine ye-radioactive (RAI) kubvisa uye kushandiswa kubviswa kwezvose kana chikamu chetachiona chetachiona .
Iko kune miviri miviri yakakura yemitroviryroid inowanikwa muUnited States: propylthiouracil (PTU) uye methimazole. MuUnited States, methimazole inofungidzirwa kuti inodhaka yemishonga inoshandiswa nevhidhiyo mumatambudziko mazhinji.
Methimazole, dzimwe nguva inonzi thiamazole, inhibits utachiona kubva pakushandisa iodine kuti utange hormone yekemikari. Inowanzotorwa sechiitiko kamwe kamwe pazuva.
Mushonga unoshandiswa munyika yose. MuUnited States, Tapazole ndiro zita rega rega re antithyroid drug methimazole. Kune huwandu hwakawanda hwezvigadzirwa zve generic zve methimazole.
Tapazole
Tapazole ndiro zita remethimazole , mishonga inoshandiswa nevirityroid yakagadzirwa naMambo Pharmaceuticals, Inc. I FDA inobvumira Tapazole muna 2000.
Tapazole Zvisungo : methimazole USP; lactose monohydrate; magnesium stearate; starch (chibage); pregelatinized starch; uye talc.
Simba Rinowanikwa : 5 mg uye 10 mg
Generic Methimazole (by Sandoz)
Sandoz, nhengo ye Novartis Group of Companies, anogadzira methimazole. Yakagamuchirwa neRWA muna 2001.
Sandoz Methimazole Ingredients: methimazole USP; lactose monohydrate; magnesium stearate; starch (chibage); uye talc.
Simba Rinowanikwa: 5 mg uye 10 mg
Generic Methimazole (neCedar Pharmaceuticals LLC)
Cedar Pharmaceuticals LLC vanogadzira methimazole inowanzoparadzirwa neUnited Research Laboratories. FDA mvumo yakawanikwa muna 2005.
Cedar Pharmaceuticals Methimazole Zvokudya: methimazole USP; actose monohydrate; magnesium stearate; mbatata samashizha; uye talc.
Simba Rinowanikwa: 5 mg, 10 mg, 15 mg, 20 mg
Generic Methimazole (by Activis Totowa)
Activis Totowa LLC vatori ve generhima methimazole uye FDA kubvumirwa kwakawanikwa muna 2007.
Activis Methimazole Ingredients methimazole USP; lactose monohydrate; magnesium stearate; starch pregelatinized; uye talc.
Simba rinowanikwa: 5 mg uye 10 mg
Generic Methimazole (neCaraco Pharmaceutical Laboratories)
Caraco Pharmaceutical Laboratories, Ltd. inogadzira methimazole yakagamuchirwa neDFA muna 2007.
Caraco Methimazole Zvokudya: methimazole USP; lactose monohydrate; povidone; talc; croscarmellose; magnesium stearate; uye starch yegorosi.
Simba Rinowanikwa: 5mg uye 10mg
Generic Methimazole (nePar Pharmaceutical Companies)
Par Pharmaceutical Companies inogadzira methimazole.
Zvisungo: methimazole USP; lactose monohydrate; magnesium stearate; corn starch; uye talc.
Simba Rinowanikwa: 5 mg uye 10 mg
Sources:
Daily Med, US Food and Drug Administration Medication Database.
FDA Mishonga Yekuchengetedzwa Kwemishonga Kukurukurirana: Mutsva Wemabhadharo Mutsva Pamhepo Yakanyanya Kukuvara NaPropylthiouracil, Kubvumbi 21, 2010
Ross, Douglas MD, "Tsanangudzo yevarwere: mishonga yeAtithyroid," UpToDate . Yakagadziridzwa: November 13, 2009
Kuwedzera kuzivikanwa na: Leslie Blumenberg