A Tarisa AST uye ALT
Chiropa chechiropa chinokonzerwa nechiropa chinogona kuyerwa kuburikidza nekuongororwa ropa. Chiyero chezviyero izvi zvinopararira muropa rako zvinotendera vanachiremba kudzidza nezvehutano hwechiropa chako. Kune zviuru zvevhenekisi iri muropa uye ropa, asi maviri acho-aminotransferase AST neAlt-inonyanya kukosha pakuziva kuora kwechiropa uye zvirwere.
Chii Chinonzi Aminotransferases?
Aminotransferase imakemikari chiropa chinoshandisa kubatsira kubatsira simba-kuchengetedza molecule glycogen. Aspartate aminotransferase, kana AST, inowanikwa muchiropa, asiwo uropi, mascotas, mwoyo, masaga, musvo, mapapu. Alanine aminotransferase, kana ALT, inonyanya kuwanikwa muropa.
Ko Liver Enzymes Inoedzwa Sei?
Kuti uongorore AST uye ALT, chiremba anoda kuraira kuongorora kwe enzyme, iyo kazhinji inosanganisira mimwe miedzo yakawanda yakafanana ne albumin, bilirubin, uye prothrombin nguva. Imwe nyanzvi ichakwevera sampu yeropa rako uye inotumira kubhii kuti iongororwe. Zvibereko zvinotumirwa kuchiremba wako.
Chii Chisiri Chakanaka AST uye ALT Nhamba?
Izvo zvakajairika mazinga eAST neAlt anosiyana kubva kumunhu kusvika kune munhu uye anoenderana nemuviri wako mass index (BMI), kana uwandu hwehurefu hwako uye uremu. Chinhu chiduku cheAST neAlt chinowanzo muropa rako, saka iko chaizvoizvo kuwedzera kukuru pamusoro pehutano hwako hunoratidza chinetso.
Vanhu vane chirwere chinokonzerwa nehutachipatachi hepatitis vanogona kunge vane aminotransferase mazinga akakwirira kupfuura ma1000 maitirwo emarudzi pamarita ega (IU / L). Zvose zvinowanzoitwa ma laboratory mabhuku eAST uye ALT ndei:
- AST 2-45 IU / L
- ALT 2-40 IU / L
Nei AST uye ALT Inobatsira?
Nemhaka yokuti idzi maantimisi anowanikwa muropa (hepatocytes), iyo ine zvakawanda zvekubatana neropa rako, AST neAlT vanogona "kunyura" muropa kana hepatocytes iri kukuvara.
Ropa rekuongorora rinogona kusarudza kuwanda kwema enzymes muropa rako uye vanachiremba vanogona kushandisa ruzivo urwu kuti vabatsire kusvika kuongororwa kana kurongedza zvimwe zviedzo.
Zvisinganzwisisiki zvakakwirira zvezviviri zvinokonzera chiropa zvinoratidza kuti masero eropa anokanganisa, asi haagoni kutaurira chii chakakonzera kukanganisa. Nokuti kuwedzerwa kwe enzyme maitiro kunogona kuonekwa mune dzimwe zvirwere ( kurwisa kwemwoyo , kuneta, chirwere cheshuga mellitus , mononucleosis), izvo zvinongova chikamu chiduku chepikicha yakawanda. Kupa vanachiremba kliniki yakakwana, mapurogiramu enzyme anofanira kushandiswa nedzimwe kuongororwa kweropa, kuongorora kwenguva refu, uye nhoroondo yezvechiremba.
Nemhaka yokuti AST iri munzvimbo dzakawanda mumuviri, marefu eAST chete haarati zvirwere zvepachiropa (zvinoshamisa, asi zvisingaiti, kunze kwechirwere cheWilson). Zvisinei, chiyero cheAST kusvika kuAlt, kana chiyero cheAST chichienzanisa nehuwandu hweAlt, chinopa mazano mazhinji kune zviri kuitika mukati. Kubva pane izvozvi, vanachiremba vanogona kuisa pfungwa dzavo kune rumwe rudzi rwechiropa chinogona kuvapo. Heano mamwe mazano anowanzoshandiswa pachirwere chechiropa:
- Nhamba yeAST: ALT yakaenzana neyomumwe (iyo ye ALT yakakwirira kana yakaenzana neAST), asi mazinga akareba kwazvo, anoratidza chirwere chetachiona hepatitis kana hepatitis inosangana nemishonga.
- Chirongwa cheAST: ALT chakakwirira kupfuura 2: 1 (kanhi kaviri muzinga weAST kusvika kune ALT) inonyanya kuratidza chirwere chinodhaka chechiropa.
- Nhamba yeAST: ALT yakakwirira kupfuura imwe (apo mazinga eAST akareba kupfuura ALT) inogonawo kuratidza chirwere chemuviri kune munhu asina doro rehepatitis.
Verenga zvakawanda:
Sources
- Pratt DS, Kaplan MM. Kuongorora kweChiropa Basa. Mune: AS Fauci, E Braunwald, DL Kasper, SL Hauser, DL Longo, JL Jameson, J Loscaizo (eds), Harrison's Principles of Internal Medicine , 17e. New York, McGraw-Hill, 2008.