Imwe nzvimbo inofadza yekutsvakurudza kwenguva refu pane tereomeres, iyo ndiyo "mazano" pamagumo emakromosomes edu, akaumbwa nekuenzanisa kweDNA isina coding. Telomeres inotora chikamu chakakosha muhutano hwevanhu uye masayendisiti akawana kuti vakunda Nobel Prize muPhysiology kana Medicine muna 2009.
Apo masero ari kuda kugovana, DNA inofanira kudzokororwa.
Izvo ma enzymes anoita shanduro yekutanga inotanga nokuvhara kusvika kumagumo echromosome. Chikamu chekromosome iyo inoshandiswa pakugadzirisa mitambo haikwanisi kunyoreswa, saka nekuparadzaniswa kweesezi rimwe nerimwe, chromosome inenge ichinyanya kuva shoma. Telomere shortening is an indicator of cellular aging. Telomeres ndiyo DNA zvikamu pamigumo ye-chromosomes inopa nzvimbo yemichina yekudzorera inobatanidza, kuitira kuti DNA chinyorwa chinogona kunyorwa zvachose. Kuti imwezve kudzokorora kuitike, inofanira kunge yakakwana ye telomere yakasara kuti ipe nzvimbo yezvinyorwa zvekudzorerazve kuisa, kuchengetedza geni rekodhi yepamusoro pairi yakasimba uye inowanikwa kuti inyore. Kana tereomere ikava shoma shoma, kudzokorora kweDNA kunogadziriswa, uye sero haigoni kugovana. Masero ane maitiro ehupenyu panzvimbo yekuchengetedza tereomere. Iyo enzyme telomerase inovakazve tereomere, kubhadhara kupfupisa kunoitika nega rega sega rega.
Kukwegura Kwemawere Kunotungamirira kune Cellular Senescence
Kukwegura kwemasero, iyo inosanganisira tetomere shortening uye DNA kukanganisa, pakupedzisira inoguma necheescence, mamiriro ekusimudza masero. Sero iri richiri kurarama, asi harina utano uye harisi kukwanisa kugovana. Sezvo masero akawanda uye akawanda ari mumashuga anova nesenecenti, chaizvoizvo chimiro chiri kuchembera, basa rayo rinoshandiswa.
Masero eSenocent haakwanisi kuita zviyero zvemasero, anoparadza simba redu rekugadzirisa kukanganisa, uye secrete zvinhu zvinokanganisa kushanda kwemasero akavakidzana uye kukurudzira kukura kwekenza.
Shorter Telomeres yakabatanidzwa kune zvirwere
Basa reTelomere kureba uye tereomasease rinogona kuyerwa mumasero evanhu vemazimbe eropa, uye izvi zvakapa vaongorori kukwanisa kutsvaga zvinhu uye zvirwere zvinosanganisira zvibvumirano kune aya masheji ekukwegura.
Muzvidzidzo zvevanhu, shorter tereomere kureba kana basa rezasi re telomerase rave richibatanidzwa nezviitiko zvisingaverengeki, zvirwere zvinodzivirirwa, zvinosanganisira kuwedzera kwehutano, hutachiona hwehutachiona, chirwere chechirwere cheshuga, kuora mwoyo, osteoporosis, uye kuneta.
Zvokudya uye Upenyu Hwezvinhu Zvinobatsira Terefere Kureba
Basa reTelomere kureba uye tereomasease zvakagadziriswa nezvose zvinokonzera mazamu uye zvakatipoteredza, kusanganisira kudya uye mararamiro ehupenyu. Nhamba dzakakwirira dzezvirimwa nemichero kushandiswa, fiber intake, vitamini uye mineral kudya, uye kurovedza muviri zvinhu zvinobatanidzwa nemazuva akawanda tereomere uye basa guru re telomerase. Kuchengetedza terefomu kunoratidzika kuva imwe yenzira dzakawanda iyo mafambiro aya anopa mararamiro akanaka anokurudzira hupenyu hurefu.
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