Tarisa neGastroenterologist Yenyu Usati Watora Painkiller
Tarisa munharaunda chero ipi zvayo yemishonga cabinet uye iwe unogona kuwana NSAID (isina-steroidal anti-inflammatory drug). NSAIDs, iyo inoshandiswa kurapa marwadzo nekuputika, yakakurumbira zvokuti inowanzova nekana yavo muzvigadzirwa zve drugstores. Zvechokwadi, kutarisirwa kunoda kutorwa kuti kuve nechokwadi chokuti vanhu havaiti nengozi kutenga NSAIDS dzakawanda, kunyanya nokuti zvinogona kuva nyore kushandisa zvinopfuura imwe yei zvinopfuura zve-zvinodhaka zvinodhaka kupora marwadzo uye fevha kubva kune furu kana zvimwewo zvakajairika kurwara.
Zvimwe zvinoshandiswa zveNSAID zvinosanganisira kurapa misoro, kurwadziwa kwemisvo, kumwedzi kwemazuva uye kubvisa mazuva ose uye marwadzo.
Vanhu vane chirwere chinoputika chirwere (IBD) vanoziva aches nemarwadzo semunhu wese. Vakawanda vanorwadziwawo zuva nezuva nekuda kwemamwe emitemo yakadai seArthritis kana kubva pamigumisiro yemishonga yakadai kubva mukurapa misoro. Zvisinei, vamwe gastroenterologists vanokurudzira kuti varwere vavo veBDI vasiye kure neNSAIDs. Chikonzero: NSAIDs dzinogona kuva nemigumisiro yakaipa paCrohn's disease uye ulcerative colitis.
Nzira dzeNSAID dzinoshanda sei
NSAIDs inoshanda nekuvhara maviri enzymes mumuviri: cyclooxygenase-1 (COX-1) uye cyclooxygenase-2 (COX-2) . COX-1 inobatanidzwa mumagadzirirwo emagetsi uye COX-2 inobatanidzwa mubasa rinopisa. Basa re COX-1 nderokutonga zvinhu zvinonzi prostaglandins zvinodzivirira chigadziko chemuviri kubva kune acid dzinobatsira kudya zvokudya.
I-prostaglandin yakagadzirirwa ne COX-2 inopindira chirwere chekuvhiringidza uye kupindura kunorwadza.
Izvi zvinorevei kuti apo NSAID dzinoderedza kupoteredza kwekuvhiringidzika uye kurwadziwa, zvinokonzera kuti chirwere chekudya chirasikirwe zvimwe zvezvinhu zvayo zvinodzivirira. Izvi zvinogona kusimbisa matambudziko akawanda kune avo vanotova nekuputika, kana kukwanisa kwekuvhiringidza, mumugwagwa wavo wekudya.
NSAIDs Uye Ulcers
Kunyangwe mune vanhu vasina IBD, NSAIDs inogona kuita kuti zviputi zvive mudumbu uye chikamu chokutanga chemukati mudumbu ( duodenum ). NSAIDs dzinogona kukonzera kutuka uye kuwedzera kubuda ropa mumucheche muduku. Dzimwe nyanzvi dzekudya dzinonetseka kuti NSAID dzinogona kukonzera IBD kuti ibude mukuregererwa .
NSAIDs Uye IBD
Kutsvakurudza pamusoro pekuti NSAID dzinobatsira zviratidzo zveBD zvinopesana, zvichiita kuti pave nokukakavara pakushandiswa kwavo pakati pegastroenterologists. Kukirasi yemishonga inonzi COX-2 inhibitors, pane ikozvino haisi huzhinji huchapupu mumigumisiro yayo kune vanhu vane IBD. Imwe tsvakurudzo inoratidza kuti NSAIDs inogona kungoita humwe huwandu huwandu hwevanhu vane IBD, asi hazvibviri kuziva kuti ndiani achabatwa uye asingaiti. Zvakambofungidzirwa kuti kushandisa COX-2 inhibitor, panzvimbo pemishonga iyo yose COX-1 uye COX-2 inhibitor, inogona kushandiswa nekuchenjerera kune avo vane IBD vakanga vari mukuregererwa.
Vanhu vane IBD vanofanira kubvunzurudza gastroenterologist yavo vasati vatora NSAIDs, kunyange iyo inowanikwa pane iyo. Izvi zvakakosha zvikuru kuita kuti nhengo dzose dzedare rehutano hwehutano dzizivikanwe nemigumisiro yeNSAID inogona kuva neBDD yavo.
Izvo Avo Vane IBD Vanogona Kuita
Vanhu vane IBD avo vari kutsvaga rubatsiro rwepamusoro-rwe-ronda runogona kuda kufungidzira acetaminophen.
Acetaminophen, inotengeswa pasi pemazita akawanda emishonga, kusanganisira Tylenol, haisi NSAID uye inogona kuva sarudzo yakanaka kune vanhu vane IBD vanoda chirwere chekurwadza. Iyo acetaminophen inoshanda kubvisa marwadzo hainzwisisi zvachose, asi inofungidzirwa kuti inosanganisira kurega kusikwa kwe prostaglandin.
Nguva dzose mubvunze kuwedzerwa kwemishonga mishonga mitsva, kunyanya iyo inoshandiswa kugadzirisa marwadzo. Kwete vese vehutano vehutano vanoziva nezvekukwanisa kushamwaridzana pakati pepaillillers neBD. Apo vanhu vane IBD vachazovhiyiwa kana maitiro, zvakakosha kuvhara gastroenterologist mune zvekukurukurirana pamusoro pekununurwa kwekutambudzika kuti uve nechokwadi chokuti une ruzivo rwezvino pamusoro peNSAID uye kuti dzinoshanda sei kwauri.
Pasi pane tafura yeNSAIDs inowanikwa nemutemo kana kuti pamusoro pekambani. Izvi hazvirevi mazita akazara, saka tapota taurirana nemumwe mishonga kana kuti chiremba nezvekunyanya kunetseka nezvemishonga chaiyo.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
| Zita Rekushandisa | Zita rechizvarwa |
| Advil, Excedrin IB, Genpril, Haltran, Ibuprin, Ibuprohm, Ibu-Tab, Midrin 200, Medipren, Midol IB, Motrin, Nuprin, Pamprin-IB, Rufen, Trendar | Ibuprofen |
| Aleve, Anaprox, Naprosyn | Naproxen Sodium |
| Amigesic, Anaflex 750, Marthritic, Mono-Gesic, Salflex, Salsitab, Disalcid | Salsalate |
| Anacin, Bayer, Bufferin, Ecotrin | Choline salicylate |
| Shamba, Froben | Flurbiprofen Oral |
| Apo-Keto, Orudis, Oruvail, Rhodis | Ketoprofen |
| Apo-Sulin, Clinoril, Novo-Sundac | Sulindac |
| Aspergum, Genuine Bayer, Bayer Childrens, Bufferin, Easprin, Ecotrin, Empirin, Genprin, Halfprin, Magnaprin, ZORprin | Aspirin |
| Butazolidin | Phenylbutazone |
| Cataflam, Voltaren | Diclofenac Systemic |
| DayPro | Oxaprozin |
| Dolobid | Diflunisal |
| Feldene, Novo-Pirocam, Nu-Pirox | Piroxicam |
| Indocin SR, Indocid, Novo-Methacin | Indomethacin |
| Lodine | Etodolac |
| Meclomen | Meclofenamate Sodium |
| Mobic | Meloxicam |
| Nalfon | Fenoprofen Calcium |
| Ponstan, Ponstel | Meclofenamic acid |
| Relafen | Nabumetone |
| Tolectin | Tolmetin Sodium |
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