Chirwere Chizhinji cheMapirini ePasinsinson Mishonga
Kudzorera dopamine nenzira yezvinodhaka carbidopa / levodopa ndeimwe yemishonga yakanyatsonaka-yakagadzirwa mune neurology uye inobvumira varwere vane chirwere chePasinson chimwe chekuzorora kubva mukudengenyeka kwavo uye kusagadzikana. Zvisinei, dzimwe nguva, dopamine kudzokera kunouya nemigumisiro. Zvose zvinonyanya kuzivikanwa pane izvi zvinosanganisira hypermobility (kunyanya kufamba) kana kunyange kutengesa.
Dopamine dysregulation syndrome (DDS) chimwe chikonzero chinogona kuitika, chinoitika munenge 4 muzana yevarwere pane dopaminergic therapy.
Zviratidzo zveDopamine Dysregulation Syndrome
Chiratidzo chinowanzozivikanwa che dopamine dysregulation inomanikidzika chido chePasinson mishonga se carbidopa / levodopa . Kunyange kana pasina zviratidzo zviriko (sekudengenyeka kana kusagadzikana), murwere anogona kunzwa zvakasimba kuti vanoda chirwere. Vamwe vangaedza kuenzanisa zviratidzo zvavo zvePasinsonia kana kupa chiokomuhomwe shamwari kana nhengo dzemhuri kuti vawane mishonga inoda - iyi ndiyo yakasimba kushuva.
Mukuwedzera, vanhu vane dopamine dysregulation syndrome vanogona kunzwa vaine simba kana euphoric, uye pasina mushonga, vanogona kunzwa vaora mwoyo kana vachinetseka. Uyezve, matambudziko ekudzora simba, sekumanikidzika kubhejera kana kutenga, kutambudzika kwekudya kana zvimwe zvinodhaka, zvinogona kuitika, semugumisiro we dopamine dysregulation.
Zvimwe zvinoremedza maitiro ekunyengera, zvakadai sokuunganidza zvinhu kana kuisa zvinhu zvisiri nyore mumutsara, zvinogonawo kuonekwa. Zviratidzo zvakajeka zvakadai sepfungwa inobvirawo mune iyi syndrome
Chii chinokonzera Dopamine Dysregulation Syndrome?
Dopamine inobatanidza nemubairo wehutano yedu pachitsime chemaodzanyemba, kusanganisira ventral tegmental nzvimbo .
Zvechokwadi, zvinodhaka zvinodhaka, zvakadai secocaine, zvinokurudzira dopamine kusunungurwa munharaunda iyi. Dopamine basa munzvimbo ino yeuropi yakatenda kuti inokonzera dopamine dysregulation syndrome. Izvo zvinotaurwa, nzira chaiyo hadzina kunzwisiswa. Uyezve, kana dopamine yakakosha kune zvose kufamba uye mubhadharo wehurongwa, zvichida zvinoshamisa kuti DDS haina kufanana.
Kana chirwere chinodhaka chichipiwa, mubairo wekodzero unogona kugara kune huwandu hwemubairo, unoda huwandu hwekupa zvakafanana. Tinoziva kuti izvi ndezvokwadi nedopamine therapy muPasinson's - maitiro makuru anozopedzisira adikanwa kuti aite zvakafanana. Kunyange zvazvo zvimwe zveizvi zvichida nekuda kwekuwedzera kwechirwere, vamwe masayendisiti mubvunzo kana izvi zvinowedzera zvinogona kuratidza rudzi rwekugara, izvo muhutano hwemararamiro, zvingaguma nemhando yekuda.
Ndiani Anowana Dopamine Dysregulation Syndrome?
Kuwanikwa kweDDS kunoratidza kuti vanhu vakawanda vanodzivirirwa pane chirwere, asi vamwe vanogona kunge vane ngozi dzekuvandudza chirwere. Varume vane zvirwere zvepakutanga vangave vari pangozi yakanyanya. Mamwe maitiro ekumanikidzika, zvakadai sekushandisa zvinodhaka, ndeimwe yezvipingamupinyi zvakanyanya.
Dopamine Dysregulation Syndrome Inotarirwa Sei?
Nokuti varwere vane DDS vanonyanya kuva nechinodhaka kune mishonga iyo inodawo kuti ishande, mushonga wakanakisisa unosanganisira maitiro akaoma e dopamine kana dopamine agonists (mishonga inobatsira dopamine receptors). Kuderedza zviratidzo zvinoderera sezvo chirwere chemishonga chinoderedzwa. Sezvimwe nezvimwe zvinodhaka, rubatsiro rwemagariro evanhu huchadikanwa kubatsira kubatsira kuti mishonga inotorwa sezvinorayirwa uye kugadzirisa mamwe maitiro ekumanikidzira. Mune zviitiko zvakanyanya, antipsychotics inogona kuva yakakosha kugadzirisa chisimba kana psychosis, kunyange izvi zvinowedzera njodzi yekuwedzera zviratidzo zvehosha yaPasinson.
Pasi Pasi
Dopamine inonzi neurotransmitter yakaoma inokonzera kufamba kwedu, chikonzero chedu, uye mubayiro wedu nenzira dzatisati tisinganyatsonzwisisi, pasinei makumi emakore ekudzidza. Kunyange zvazvo dopamine dysregulation syndrome isingawaniki muhosha yaPasinson, inogona kuitika, uye kupindira kwakanakisisa ndeyokutanga uye kwakatsigirwa nechiremba wemunhu akabatwa, mutarisiri, uye / kana vadiwa.
Sources:
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