Mukutanga kwemakore ekuma1940, masayendisiti akanga aona kuti vanhu vaine chiedza chakanyanya chezuva vaiva nemapurisa akakura emukanda weganda, asi mazana emadhora eimwe kenza. Kwemakore aya, zvidzidzo zvakawana kuchinja kwemajeri muhuwandu hwemasero makumi maviri nemaviri evanhu vane mararamiro akasiyana-siyana ekenza munzvimbo dzakanyanya kufanana nezuva.
Nhasi, zvakajeka kuti vitamini D inonyanya kukonzera kupesana uku, uye tine uchapupu hwakasimba hwokuti kuchengetedza hutano hwakakwana hwevhitamin D hunobatsira kuchengetedza mhando dzakawanda dzekenza yepabonde dzakabatana, pamwe nehutachiona hwehutachiona, mamiriro ezvinhu ega autommune, uye zvechokwadi osteoporosis.
The Link Between Vitamin D uye Breast Cancer
Pakati pevakadzi vane kenza yemazamu , vanenge 75 muzana havana kukwana muvhitamini D. Vakadzi vane zvirwere zvakakwana zvevhitamini D zvishoma hazviwanike kuti vane kenza yemazamu, uye avo vanotova nekenza yemazamu havakwanisi kuwanazve chirwere ichi kana mavhithamini avo eVitamini D akakwana. Muna 2014, meta-kuongorora mitsva 56 yakagumisa kuti vitamini D3 supplementation yakabatanidzwa ne12 muzana kuderedza mudambudziko rekufa kubva kune kenza chero ipi zvayo.
Vitamini D inogona kunge yakanyanyisa kurwisa kenza yemazamu. Izvi zvingave zvakasimudzwa apo chidzidzo chevakadzi vanopfuura 57 000 postmenopausal vakawana kuti vakadzi vakatora vitamin D kuwedzera kwaive ne 26 muzana kuderedza mukana wekenza yemazamu. Chii chakaita kuti kuwanikwa uku kuve kunonyanya kukosha ndechokuti zvakaitika kune vakadzi vakashandisawo hormone replacement therapy .
Kushandiswa kweHommone replacement therapy mumasikatiopausal vakadzi vakaderera zvakanyanya mushure me2002, apo chidzidzo chikuru, chainzi Women's Health Initiative, chakamiswa kare nekuda kwekuwedzera kwengozi yepfungwa yepfungwa, kurwara, uye kenza yemazamu muboka rinogamuchira hormone therapy.
Estrogen inozivikanwa kukurudzira kukura uye kupararira kwemasero emukamu webonde.
Kuwedzerwa kuwedzerwa kune estrogen, nekuda kwezvinhu zvakadai sekutanga kwekuenda kumwedzi uye kuwedzera muviri wemafuta , zvinosanganiswa nemukana mukuru wekenza yemazamu. Vitamini D zvinowedzera zvinogona kunge zvakapesana nekenza-kukurudzira zvinokonzerwa nemahomoni.
Zvimwe zvinokonzera kudya zvinopesana nezviito kana kugadzirwa kweestrogen zvinosangana nehuwandu huripo hwekenza yemazamu. Mienzaniso mishomanana: mushroom ane aromatase inhibitors (aromatase is enzyme inobereka estrogen); soya uye firk uye mbeu dzechia dzine phytoestrogens dzine anti-estrogenic migumisiro; imwe yezvokudya zvepamusoro inobatsira kushandiswa kweexrogen. Vitamini D inoratidzika kuva nemigumisiro yakafanana.
Maererano nezvinyorwa zve vitrosi pamasero epabonde, chimiro chinoshandiswa che vitamini D chinoderedza aromatase kutaura, zvichiguma nekugadzirwa kwepasi kweesrogen. Vitamin D yave ichiratidzwawo kuderedza nhamba yeestrogen receptors pamagariro echetere echembera, zvichiita kuti masero asapindirana nemasikironi ekukurudzira kenza.
Is Sunshine Yakakwana Here?
Vitamini D inoshandiswa paganda iri kusiyana pakati pevanhu. Hapana nguva yakajeka yezuva nezuva kusvikirwa kwezuva kuchashanda kune umwe neumwe, uye kune vazhinji vedu, kuwandisa kwezuva kwakakwana hakuzokwanisi.
Mune chidzidzo che vagari veHawaii vane chiedza chikuru chezuva-inenge yemaawa makumi maviri nemaviri pavhiki-anenge makumi mashanu kubva muzana yekare vaine vitamin D pasi pe 30 ng / ml. Kunyanya, vamwe vedu tinorarama munzvimbo dzakakwirira dzinoita kuti Vitamin D iwane zvakaoma.
Nzira yakanakisisa yekuziva nayo ndeyekuti une 25 (OH) D yeropa test. Tinokurudzira kushandisa shanduro kuti tiwane nzvimbo yakanaka ye 30-45 ng / ml. Kune vanhu vazhinji, muwandu wezuva nezuva wekuwedzera mavitamini D3 (anenge 1000-2000 IU / zuva) yakakodzera kusvika iyo iyo 30-45 ng / ml hwindo.
> Sources:
> Grant WB. Zvidzidzo zvehupenyu hweVBB-vitamini D-kenza pfungwa. Anticancer Res 2012, 32: 223-236.
> Krishnan AV, Swami S, Feldman D. Mikana inogona kurapa mavitamini D mukurapwa kweestrogen receptor positive kenza yemazamu. Steroids 2012, 77: 1107-1112.
> Cadeau C, Fournier A, Mesrine S, et al. Kuwirirana pakati pezvino mavitamini D supplementation uye menopausal hormone therapy inoshandiswa pahutachiwana hwekenza yemazamu: uchapupu hunobva kuboka reE3N. Am J Clin Nutritio 2015, 102: 966-973.
> Binkley N, Novotny R, Krueger D, et al. Low vitamin D mamiriro ezvinhu pasinei nekuwanda kwezuva. J Clin Endocrinol Metab 2007, 92: 2130-2135.
> Bischoff-Ferrari HA. Optimal serum 25-hydroxyvitamin D maitiro emigumisiro yakawanda yehutano. Adv Exp Med Biol 2008, 624: 55-71.