Tisati tatanga, ndinoda kusimbisa kuti kune avo vanofarira nyaya yose yekurapa kwechirwere chepabonde , iyi nyaya pamusoro pe testosterone patch inofanira kuverengwa mukati mechirevo chezvimwe zvikamu zviviri zvandakanyora: Zvinorambidza vakadzi uye itsva-asi isina kufanirwa - yepabonde yepabonde yepabonde flibanserin . Kunyanya zvakanyanya, testosterone patch inomiririra chikamu chepakati chechikadzi chepabonde chinokonzerwa nekuita zvepabonde: chekuedza kwakaedzwa pashure pokunge Pfizer akamira kusunungura Viagra nekuda kwevakadzi uye vasati vatanga kufambiswa kweflibanserin, mishonga yemukadzi yepabonde inobatanidza neurotransmitter mazinga.
Zvidzidzo pamusoro pekusagadzikana kwevakadzikadzi
Kuda kwemaitiro ose ekuedza kurapwa kwevakadzi vanoita zvepabonde zvisina kukodzera kusvika kune imwe nyaya yakabudiswa muna 1999 inonzi JAMA iyo inowanzonzi "43-31" kudzidza. Vatsvakurudzi vanobva pakuongorora uku vanoratidza kuti vakadzi vanopfuura 4 pa10 (43 muzana) vane matambudziko epabonde kana vachienzaniswa ne31 muzana yevarume. Ichi chidzidzo chakaratidza izvo zvinoramba zvichiramba mumakakatanwa ose pamusoro pekurapa kwekusagadzikana kwevakadzi pabonde; iyo inokonzera makambani ekurapa nemishonga uye vadzidzisi vakawanda vezvepabonde kune rumwe rutivi, nevatsoropodzi vanotaura kuti kuvhiringidza hutano hwepabonde pane imwezve muenzaniso we "chirwere chekuita" kune rumwe rutivi.
Musi waJune 21, 2004, Proctor & Gamble vakashandisa FDA kubvumidzwa kwayo itsva ye transdermal testosterone system (jargonese ye testosterone patch), Intrinsa. Intrinsa yakarongwa se:
Kurapa kwehupenzi hwehupombwe hwechido chepabonde muvakadzi vane chirwere chinonzi menopausal vanogadziriswa nesrogen therapy. Kuita zvepabonde chishuwo chekuita zvepabonde (HSDD) ndiko kukanganiswa kunoramba kuripo kana kukanganisa kana kusavapo kwepfungwa dzepabonde, mafungiro, uye / kana chido chekugamuchira kana kugamuchira zvepabonde, izvo zvinokonzera kushungurudzika kwega kana kuti zvinetso zvemunhu. Chido chepabonde chepabonde chingave chakabatanidzwa nekuita zvepabonde zvakaderera, zvinetso zvekuita zvepabonde kana dambudziko rehuguru.
Sezvakataurwa mubhuku rangu rekare rekuvhara kwepabonde kwevakadzi , HSDD isati yasvika nguva. Mazuva ano, DSM-5 inotaura nezve "chikadzi chekuita zvepabonde / chirwere chekufarira" chinosangana nezvinetso zvechido uye zvinomutsa mune imwe kliniki.
Migumisiro inobva kuP & G's Phase 3 mishonga yemakirini inoratidza kuti kune vakadzi vane 2 kusvika 3 zviitiko zvekuita zvepabonde pamwedzi, kutungamirirwa kwe 300 μg (asi kwete 150 μg kana 450 μg) kwakabatanidzwa kune imwe yegadziriro inogutsa yekuita zvepabonde pamwedzi.
Nokuda kwezvikonzero zviviri zviri pachena, FDA yakaramba kugamuchira Intrinsa. Kutanga, izvi zvinowanikwa mune zvirwere zvisingaverengeki. Muvanhu vakatova nekuita zvepabonde nguva dzose uye inogutsa , testosterone patch inowedzera nhamba yezviitiko zvinogutsa zvepabonde imwe pamwedzi! Chechipiri, nokuda kwechiitiko chimwe chete chinogutsa chepabonde, vakadzi vane chirwere chokuvhiya vasati vamboita vasati vatora isrogen vaizoonekwa kune imwe ingangodaro inotyisa hormone, testosterone. Rega ndikutsanangurire.
Pakazosvika nguva iyo P & G yakanyorera kubvumirwa kwayo testosterone patch, munhu wese aive achibuda kunze kwezvibereko zvaibuda kubva kuImai Women's Health Initiative kuongorora hormone supplementation. Panguva iyoyo, migumisiro kubva kune idzi zvidzidzo zvinonzi kushandiswa kweesrogen uye progesterone kuvakadzi mushure-hysterectomy yakawedzera dambudziko rezviitiko zvinokanganisa (kufunga chirwere), zvirwere zvepfungwa uye kenza yemazamu. Iyo FDA yakagumisa kuti pasina humwe huwandu hwekudzidza kwenguva refu, zvinogona kutyisa kupa postmenopausal vakadzi testosterone nemamwe mahomoni. Zvinyorwa, P & G yekudzidza kwepakutanga yakaratidza testosterone supplementation mumubatanidzwa kwemavhiki 52 panguva yakawanda.
Muchiedza chekudzingwa kweDFA, P & G akaona kusakosha kwekusimudzira nyaya yacho ndokuderedza Intrinsa.
Mukuonazve, zvakajeka kuti P & G aitarisira kuti vanachiremba vaizopa testosterone chikwata chekuregererwa kwemavara-kunyanya, kune vakadzi kunze kweavo vakambonzwa mushure mekuvhiyiwa kwemwedzi. Nokushayikwa kwekudzidza kwenguva refu, zvisinei, iyo FDA yakave yakashungurudzika nemukana uyu.
Pane zvimwe zvitsvakurudzo zvinotsvakurudza izvo zvinokonzera kuve nekubudirira kwe testosterone sekupindira kune vanhu vane hutano hwevakadzi pabonde / tsvakurudzo yekufarira. Chokutanga, hatina uchapupu hwehutachiona hwehutanoji hwevakadzi nehutano hwepabonde. Chechipiri, kunyange zvazvo tichikwanisa kuverenga intracrine kana mazinga e testosterone, hatigoni kuyera maitiro e testosterone mukati mehutano hwenheyo.
Maitiro eTesttosterone mukati memitemo yenheyo inogona kunge yakakosha zvikuru pakukwira uye kuchida.
Vakadzi Vanoda Zvakawanda Testosterone?
Mune mamwe mazwi, hatina zivo kana testosterone inowanikwa muuropi nemutsipa wepelinha yevaya vane hutano hwepabonde hwevakadzi vane kukwana kwakakwana kuti vawane testosterone supplementation yakawanda, kutanga. Chechitatu, kunyange mu testosterone gels uye mapepa akaitwa pakubata vanhu, hatizivi kuti testosterone inowanikwa sei zvino kuita tsika ye testosterone supplementation zvakanyanya pamusoro.
Asi iyi ndiyo chinhu. Kune vakadzi vazhinji, kupinda kwa testosterone mune imwe nzira kunogona kuitika. Semuenzaniso, vakadzi vane chirwere chepabonde chinokonzera zvepabonde / chirwere chekufarira vanogona kugadzirirwa ma testosterone gels uye mavara kubva kunze-mavara (kutora mishonga yevarume). Testosterone kuwedzera zvinowanikwawo mavara naturopathic anogona kutengwa paIndaneti. Pakupedzisira, kune dzimwe nyika, testosterone dzimwe nguva inopiwa kuvadzimai vane hutano hwevakadzi hwepabonde.
Nokudaro zvose mune zvose, kunezve nzira dzekuisa maoko ako pane testosterone kuti uite zvekuita zvepabonde zvisina kunaka zvevakadzi ; zvisinei, zvakapiwa izvo zvatinoziva, zvichida chinangwa chakanaka chekusiya zvinhu. Kutsvakurudza kunoratidza kuti hakuna chiremba inobatsira testosterone supplementation kuvakadzi vane hutano hwevakadzi hwepabonde, pamwe chete hatitombozivi kana maitiro e testosterone ari akakwana kuvakadzi vane hutano hwepabonde pakutanga. Uye, zvechokwadi, testosterone ihomoni, uye mahomoni ave achizivikanwa kuti angave nemigumisiro yakaipa seyokurohwa, ropavha, ropa, nezvimwewo.
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> Nyaya > inonzi "Testosterone therapy yekuderedza libido muvakadzi" naR Basson yakabudiswa muTherapeutic Advances mu Endocrinology uye Metabolism yakabudiswa muna 2010. Yakasvika musi wa3/13/2015.
> Nyaya > inonzi "Kubvongodzwa Kwechirwere: Mishonga Yezvinodhaka Kuedza Kuumba uye Kuchinja Mishonga Yezvepabonde Kwevakadzi" naHeather Hartley yakabudiswa mune zvepabonde muna 2006. Yakasvika musi wa3/15/2015.