Restless Leg Syndrome kana Willis-Ekbom Disease

1 -

Kusakwana Kwesimbi

Kunyange zvazvo vanhu vakawanda vane maitiro emakumbo asina kusununguka (RLS) vangazombokwanisi kuziva chikonzero chechirwere chavo, kazhinji kunoguma kune zvimwe zvikonzero zvechipiri. Izvi zvinoguma muzvikamu zviviri zvechiitiko, chekutanga RLS (yezvikonzero zvisingazivikanwi uye kazhinji mhuri) uye yechipiri RLS. Kune mamiriro mazhinji ezvinhu anogona kuzvimiririra kutungamirira kune zviratidzo zveRLS.

Mamiriro ekutanga anogona kutungamirira kune zviratidzo zveRLS inoshaya simba. Ukama huri pakati pekushaiwa kwesimbi uye RLS zviratidzo zvakanyatsodzidza. Mune zvidzidzo zvakasiyana-siyana zvekutsvakurudza, zvakaderera simbi zvakawanikwa muropa neropa remusana revanhu vanotambura neRLS. Iyo yakaderera simbi yakawanda, yakaipisisa zviratidzo. Magnetic resonance imaging (MRI) yakaratidza kuti zvinyorwa zvesimbi munzvimbo yeuropi zvinonzi substantia nigra zvakaderera kune avo vane RLS kana vachienzaniswa nevanhu vanowanzogara, izvo zvinogona kuita kuti chirwere chacho chiite. Mukuwedzera, zvidzidzo zvepfungwa zvakatsigira kuchinja uku mukati meuropi.

Saka zvakakurudzirwa kuti uve neserum ferritin yepamusoro (chiratidzo chesimbi chesimbi) chekuongorora kana iwe une zviratidzo zveRLS. Mukuwedzera, chiyero chemukati chesimbi chinogadziriswa kana mazinga ari pasi anofanira kuitwa. Kunyange vamwe vanhu vane maitiro akaenzana vanopindura zvakanaka kune iron inotsiviwa.

2 -

Mugumo-gwara Chirwere Chirwere

RLS yakakurumbira pakati pevanhu vanotambura nechirwere chemagumo ekupedzisira, kunyanya avo vanovimba ne dialysis. Chiitiko chacho chave chakataurwa kuti chinobva kubva 6 kusvika ku60 muzana. Hazvizivikanwe izvo zvingangodaro zvichibatsira kuRLS muboka iri. Anemia, kuperevedza kwesimbi, kana kunyange mashoma horhemone mahomoni anogona kuva nechinangwa kubva pane zvidzidzo zvakasiyana-siyana. Mune zvimwe zviitiko, kurapa chirwere chinonzi anemia ne erythropoietin therapy kana kushandiswa kwesimbi kwakashanda.

3 -

Chirwere cheshuga

Muvanhu vane Chirwere chechipiri kana kuti munhu mukuru wehutachiona, RLS inogona kukura. Kana chirwere cheshuga chakasara chisina kudzora, utano hwemhutu hunogona kuguma. Izvi zvinofungidzirwa kuti zvinoitika nekuda kwehuwandu hweglucose mukati meropa. Izvi zvinogona kukonzera kukanganisa kwemidziyo midzi yeropa inopa mishonga inonzi vaso nervorum. Kana izvi zvikavharwa, mushupa pachahwo huchakuvara. Kazhinji izvi zvinotungamirira kune chirwere chepfungwa chinokonzerwa neuropathy, chinosanganisira kurwadziwa uye pini-uye-nenyuchi kunzwa mune tsoka. Izvi zvinogona kufambira mberi nemakumbo uye kunyange kusanganisira maoko. Kushamwaridzana nekuchinja kwekunzwa, vamwe vanhu vachange vane zviratidzo zveRLS. Nokudaro, zvinofungidzirwa kuti chirwere cheshuga chingave chakazvimirira pangozi yekuvandudza RLS. Mune vanhu vakave nekanyunyuta uye mafungiro anoputika, zviratidzo zvavo zveRLS zvakavandudzwa.

4 -

Multiple Sclerosis

Kune humwe humwe huri huno huchapupu hunoratidza kuti multiple sclerosis inoratidzika kunge inobatanidzwa nehuwandu hwehuwandu hweRLS. Zvimwe zvezvidzidzo zvinopesana, zvakadaro. Mune imwe yezvidzidzo zvakakura zvaisanganisira zvidzidzo 1 500, kupararira kweRLS kwaive ne19 muzana kune vanhu vane MS vachienzanisa ne4 chete yezana yevanhu ivavo vasina.

5 -

Zvirwere zvePacinsinson

Inofungidzirwa kuti chirwere cheRLS nePasinson chinogona kukonzerwa nechinetso chakafanana, kureva kukanganisa mu neurotransmitter dopamine. Izvi hazvinyatsonzwisiswi, zvakadaro. Pasinei nokuti, RLS inogona kunge iripo kune vanhu vane chirwere chePasinson, vane huwandu hwepamusoro kubva pa 0 kusvika ku20,8 muzana, zvakasiyana zvichienderana nekudzidza. Chirwere chePacinsins chinowanzobatanidza pfungwa yekusazorora (inonzi akathisia) inowanikwa neRLS, iyo inogona kuita kuti zvive zvakaoma kusiyanisa pakati pezvinetso. Kana zvose zviripo zviripo, RLS inowanzoitika mushure mekunge chirwere chePalinson chave chakajeka.

6 -

Kuberekwa

Kwete yose mamiriro ezvinhu anogona kutungamirira kuRLS inetso. Kutaura zvazviri, kuva nepamuviri kunoratidzika kuwedzera kwete kungoitika chete asiwo nehuwandu hwezviratidzo zveRLS. Mukudzidza 626 vakadzi vane pamuviri, gumi chete muzana vaiva nezviratidzo zveRLS vasati vava nepamuviri asi izvi zvakawedzera kusvika 27 muzana panguva yekuzvitakura. Zvaiita sokuti zvakanyanya kuwedzera muchitatu chemitatu. Mashoko akanaka ndeokuti zviratidzo zvinokurumidza kubudirira mushure mekusununguka. Hazvisi pachena zvinokonzera kuwedzerwa kwemaRLS panguva yekuzvitakura. Inogona kunge yakakonzerwa nehuta kana kuti kushayikwa kwevanhu kana kuti nekuda kwekuchinja kwehomoni kunobatanidza nekuve nepamuviri.

7 -

Rheumatic Disease

Pane mamiriro ezvinhu akadai se rheumatoid arthritis, Sjogren's syndrome, uye fibromyalgia iyo inogona kuva neshamwari nezviratidzo zveRLS. Uhu hukama huri pachena. Mune kumwe kuongorora, 25 kubva muzana yevanhu vane rheumatoid arthritis vane zviratidzo zveRLS vachifananidzwa ne 4% chete yevaya vane osteoarthritis. Mune imwe dzidzo, 42 kubva ku131 varwere vane fibromyalgia vaiva neRLS. Chikonzero chaicho chekushamwaridzana uku hachina kunyatsonzwisiswa.

8 -

Varicose Veji

Mune zvimwe zviitiko, ropa risina kufamba mumakumbo rakabatanidzwa neRLS. Kunyanya, maronda asina simba anokanganisa uye asinganzwisisiki ave akatongerwa. Iyi mishonga yevaricose inowanzovharwa uye yebhuruu iri muvara uye inogona kuva chiratidzo chekushaya kukwana. Mune chidzidzo chevarwere 1 397 vane varicose mitsipa, vanhu 312 vakanyunyuta nezviratidzo zveRLS.

Kurapa kwevaricose vevins kwakaratidza kuva kwakanaka mukuderedza zvimwe zvezviratidzo zveRLS. Sclerotherapy yakaita kuti kutanga kuwedzere mu 98 muzana yevanhu, nekununurwa kwakachengetwa kwemakore maviri mu 72 muzana. Mishonga yokurapa, kusanganisira hyrdoxyethylrutoside, yakaratidzawo kuti ine mwero inoshanda.

9 -

Zvimwe Mamiriro

Kunze kwemamiriro ezvinhu akarondedzerwa pamusoro apa, kune zvimwe zvakawanda zvinetso zvinoratidzika sezviri kuenderana neRLS zviratidzo. Izvi zvinosanganisira:

• Kuwedzera muviri
• Hypothyroidism
• High blood pressure
• Chirwere chemoyo
• Peripheral neuropathies
• Vitamin kukanganisa
• Kuwedzeredza kwekafini yeaffeine
• Iko shuga shoma
• Lumbosacral radiculopathy
• Spinal stenosis
• Kushandisa mianserin (mishonga inodzvinyirira)

Kana iwe uine zviratidzo zvemakumbo asingagadziki, nerufaro nekuti kune mishonga inoshanda inoshandiswa mukurapa .

> Sources:

> Allen, RP et al. "MRI Kuyera kweBongo Iron in Patients With Restless Legs Syndrome." Neurology 2001; 56: 263.

> Connor, JR et al. "Neuropathological Examination Inopa Kuora Mwoyo Usina Kuwana Iron Inowanikwa muRefless Legs Syndrome." Neurology 2003; 61: 304.

> Earley, CJ et al. "Kusakanganiswa kweCSF Kufungisisa kwaFerritin uye Transferrin muRinless Legs Syndrome." Neurology 2000; 54: 1698.

> Kavanagh, D et al. "Zvisina Mwero Mitsipa Syndrome muvarwere pa Dialysis." Am J Kidney Dis 2004; 43: 763.

> Lee, JE et al. "Zvinokonzera Kubudirira kweMakumbo Asingaregi Maitiro Syndrome muvarwere NeChipinson Disease." Mov Disord 2009; 24: 579.

> Manconi, M et al. "Mishonga isingagadziriswi nemakumbo uye pamuviri." Neurology 2004; 63: 1065. American Academy Yokurara Mushonga. "Kutsvaga Munyika Dzepasi Dambudziko Rokurara." 2nd edition. 2005.

> Manconi, M et al. "Multicenter Case-Control Yokudzidza Pamasana Emapfupa Syndrome mu Multiple Sclerosis: REMS Yokudzidza." Kurara 2008; 31: 944.

> Merlino, G. et al. "Kushamwaridzana Kwemishonga Yekusagadzikana Maitiro Nehutano Hwenhope Mukurudzi rwechipiri Chirwere cheshuga: A Case-Control Study." Kurara 2007; 30: 866.

> Walters, A. "Mishonga isingagadziriswi nemapfupa uye Periodic Limb Movements of Sleep." Continuum. Neurol 2007; 13 (3): 115-138.