Pain Relief Relief and Over-the-Counter Medication
Kuchengetwa kwemarwadzo ndicho chikuru chekurapa chinangwa chemishonga ye osteoarthritis. Kunzvimbo yekuputika, izvo zvinogona kuitika neasteoarthritis, zvakare kunonunurwa nekutora mishonga yemaperembudzi.
Analgesic Medication
Analgesics ikirasi yemishonga inoshandiswa kugadzirisa marwadzo. Analgesics inokurudzira kurwadziwa nekudzivirira zviratidzo zvinorwadza zvinopinda muuropi kana kupindira nekurodudzirwa kweuropi kwezviratidzo, pasina kubudisa anesthesia kana kurasikirwa kwekuziva.
Iko kune maitiro maviri ematgesics: kwete-narcotics uye zvinodhaka.
Kwete-nharotic Analgesics
Acetaminophen ndiyo yekurapa kwokutanga yakakurudzirwa neAmerican College of Rheumatology yekurapa osteoarthritis, kunyanya muhudyu nemabvi. Vamwe varwere, zvisinei, vanogona kuwana mishonga inopesana nekuputika (NSAIDs) kuti ive yakagadzikana mukurwirwa kunorwadza kupfuura acetaminophen. Pakave nekuongororwa uye nharo pamusoro pezvinobudirira-acetaminophen kana NSAIDs? Mhedziso ndeyokuti mishonga yekurapa inofanira kunge yakasiyana.
Narcotic Analgesics
Narcotic analgesics dzimwe nguva inorondedzerwa kune varwere vane osteoarthritis yakaoma vakakundikana dzimwe nzira dzokurapa. Ultram (tramadol) haisi nenyaya dzinodhaka asi mishonga ine dambudziko-sechiito pamwe chete nekurwadziwa kwekununura zvinhu. Ultram yakataurwa kuti inoderedza kushandiswa kweNSAID uye inobudirira kubata kurapwa kwevanorwara nehasteoarthritis.
Topical Analgesics
Mifananidzo yakanyanyisa mifananidzo ndeyezvigadzirwa kana zvimwe zvakagadzirwa zvinoshandiswa kune sangano rakagadzirirwa kunze. Zvinotengeswa pamusoro-the-counter. Mishonga yakashanda inosanganisira:
- Counterirritants - wintergreen mafuta, camphor, eucalyptus
- Salicylates
- Capsaicin
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAID dzakaratidzirwa kuti dzakakosha kweasteoarthritis mune zvidzidzo zvakasiyana-siyana.
Sezvo maNSAID akawanda ari ekubudirira zvakaenzana kwekununurwa kwemarwadzo, chisarudzo cheNSAID chekushandisa chingave chakavakirwa pamubhadharo, chirongwa chemaji, uye pangozi yemigumisiro. Ngozi yepachiviri uye yehuta hwehutu, pamwe nehutano hwemwoyo, inofanirwa kuongororwa neNSAID kushandiswa.
NSAIDs dzinosanganisira:
- Ansaid (Flurbiprofen)
- Arthrotec (Diclofenac / Misoprostol)
- Cataflam (Diclofenac potassium)
- Clinoril (Sulindac)
- Daypro (Oxaprozin)
- Dolobid (Diflunisal)
- Feldene (Piroxicam)
- Ibuprofen (Motrin, Advil)
- Indocin (Indomethacin)
- Ketoprofen (Orudis, Oruvail)
- Lodine (Etodolac)
- Meclomen (Meclofenamate)
- Mobic (Meloxicam)
- Nalfon (Fenoprofen)
- Nhamba (Naprosyn, Aleve)
- Ponstel (Mefenamic Acid)
- Relafen (Nabumetone)
- Tolectin (Tolmetin)
- Voltaren (Diclofenac Sodium)
COX-2 Selective Inhibitors
COX-2 sarudzo inhibitor ine zvishoma zvingaita kuti zviratidzo zvepachiviri zvinyanye kudarika zvinoshandiswa neNSAID. Chiremba wako anofanira kufunga nezvekubatsirirana nekusangana nematambudziko uye fungawo mari yaunosarudza paunosarudza NSAID yakanakisisa kana COX-2 inhibitor kwauri.
NSAIDs inoshanda nekuvhara basa re enzyme, cyclooxygenase, inozivikanwawo seCCOX. Kutsvakurudza kwakaratidza kuti pane maitiro maviri, anozivikanwa se COX-1 uye COX-2. NSAIDs inobata zvose mafomu. COX-1 inobatanidzwa mukuchengetedza mishonga yakagadzikana, apo COX-2 inobatanidzwa mukuputika kwenzira.
COX-2 sarudzo inhibitors yakava yeruzhinji rweNSAIDs, uye chisarudzo chakanaka kune varwere vari pangozi yepachiviri chekudya.
Pane imwe nguva, pane zvitatu COX-2 selective inhibitors pamusika: Celebrex, Vioxx, uye Bextra. Kunyange zvazvo maviri ekupedzisira abviswa pamusika, Celebrex ndiyo chete COX-2 selective inhibitor iripo.
Localized Injections
Osteoarthritis varwere vanobatana pamwe chete kana kuvhuvhuta kunzvimbo vanogona kubatsirwa neIntra-articular corticosteroid injections .
Chimwe chirongwa chinowanikwa munzvimbo inogona kubatsira mabheti osteoarthritis varwere inosanganisira intra-articular injection ye hyaluronan kana zviwanikwa (eg, Synvisc, Orthovisc , Hyalgan, Euflexxa, Supartz).
Iyo nzira inozivikanwa seve viscosupplementation.
Sources:
Primer paRheumatic Diseases. Mharidzo 12. Yakabudiswa neArthritis Foundation. Osteoarthritis Treatment Options. Arthritis Foundation.