Nzira yeHIV Kuongororwa
Kuongororwa nehutachiwana hweHIV kunowanzoita matanho akawanda. Chiyero chekutanga chekushandiswa chinowanzo kuongorora kukuru kwekunzwa . High sensitivity tests yakagadzirirwa kuona kuti vazhinji vanogona kutapukirwa neHIV sezvinobvira. Chiyero chekutanga ichocho zvino chinoteverwa nemumwe kana humwe mimwe miedzo yakanyatsoshandiswa kuti atonge kunze kunogona kuve nehutachiwana hutachiona hweHIV. Nhoroondo, inonyanya kuwanda yezvinyorwa zvakanyatsoshandiswa zvinoshandiswa pakuongorora kuongorora ndeyeWest blot test.
Zvisinei, pane zvimwe zvidzidzo zvinogona kushandiswa zvakare.
Ko Western Western blot test inoshanda sei?
Western blots test inozivikanwa seprotein immunoblot. Iyi miedzo inoshandiswa kuongorora mapuroteni chaiwo mune muenzaniso. Nzira yekutanga yeWest blot inosanganisira kuronga mapuroteni nekureba pane gel. Zvino iyo gadhi inotungidzirwa nezvirwere zvinopinda kune mapuroteni chaiwo ari kutsvaga.
Zvisinei, apo magetsi ekuMadokero anoshandiswa kuongororwa kweHIV , izvi zvinowanzoitwa muchechi. Kazhinji, muEast Western blot test, mapuroteni asingazivikanwi ari kutsvaga neavo anozivikanwa ma antibodies . Kunyange zvakadaro, nokuda kweHIV Western blot test, masayendisiti anoshandisa majekiseni akazvigadzirirwa eprotini yeHIV uye anotarisa kuona kana kune chero zvirwere zvinopinda muropa remunhu zvinonamatira kwavari.
Kumadokero kuvhara hutachiona hweHIV kunowanzotarisa zvinorwisana nehutachiona hweHIV hunotevera:
- Mapuroteni anobva muvhavhapu yeHIV: gp41, uye gp120 / gp160.
- Mapuroteni kubva kumucheto wehutachiona: p17, p24, p55
- Mishonga inoshandiswa neHIV muhutachiona: p31, p51, p66
Kuti munhu ave nehutachiona hweHIV, anofanira kunge ane antibodies kana imwe yemapuropine emapuropine uye imwe yepuroteni yakakomba, kana kuti imwe yeiii enzymes.
Kana munhu ane zvirwere zvinopesana nekusiyana kwema protini, zvigaro zvavo zvinowanzoonekwa sezvisingagumi. Icho chigadziro chaicho chekuzivisa chigumisiro chisingagoneki chakasiyana kune imwe neimwe yeWest Western blot test. Zvisinei, chinangwa chacho nguva dzose kuderedza dambudziko rekunyengera kwakaipa kunogumbura mumwe munhu pasina chikonzero.
Indeterminate kuWestern blot zvibereko zvingave chiratidzo chetachiwana HIV . Iyi migumisiro yechiratidzo inogonawo kuitika apo vanhu vakave vakananga kana kuti vane utachiona nemamwe retroviruses , akadai seHTLV . Kazhinji, kana munhu ane unhu hutachiona hweHIV hwekuMadokero hunenge hutachiwana hutachiwana hweHIV, hutachiona hweWestern blot huchava hwakanaka kana humwe nguva yapfuura.
Kuongorora kweWestern blot kunoshandiswa sevimbiso yekusimbisa panzvimbo pekuedza kwepakutanga, sezvo zvisinganyanyi kunzwisiswa kupfuura yekutanga- ELISA kuongorora kana kuongorora RNA . Izvozvo zvinoreva kuti havakwanise kuona chirwere. Zvisinei, kuongorora kweWestern blot hakunakwanisi kupa mutezo wakaipa wekuedza mhinduro kana uchishandiswa kuratidza chiyero chekutanga chekuedza.
Kana Wave Wakaudzwa Kuti Une Indeterminate Yekuyera kweBlot Test
Kutaurirwa kuti kuWest blot test is indeterminate inogona kunyanya kunetseka kune vanhu vari kuongororwa neHIV.
Kune zvikonzero zvakawanda zvisingabatanidzwi nehutachiwana hweHIV hunogona kuita kuti chigumisiro chakadaro. Kunyange zvakadaro, vanhu vane indeterminate mabhoti ekuMadokero vanowanzorairwa kuti vatsvake kuongororwa, zvakare kana kana mushure mokunge imwe nguva yapfuura.
Kudzokorora nguva pfupi kunotsvaga kuona kana paiva nechikanganiso nenzira iyo Western yebhutta yakanga ichimhanya. Kusiyana neizvi, kurindira mwedzi kana kupfuura vasati vadzoka kunobvumira muviri wemunhu nguva yekuita mamwe ma antibodies anorwa neAIDS antigens, kana ivo vakatove vane utachiona hweHIV.
Kudzorera kunowanzogadzirisa kusagadzikana kwekuMadokero kwechikwata chekudzivirira mukati mechikonzero chakanaka kana chakaipa .
Zvisinei, kana zviitiko zvinoramba zvichienderera mberi zvichienderera mberi kutumira zviratidzo zvinokanganisa, vanachiremba vangada kuchinja kuti vashandise dzimwe nzira dzokugadzirisa kana iwe usina HIV. Hapana humwe hutachiona hweHIV hwakanaka mumamiriro ezvinhu ose.
Sources:
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