Zvimwe Zvikamu Zvikamu Zvinofanira Kuudzwa Kuchiremba Wako Zvakarurama
Chii Chinonzi Imuran (Azathioprin)?
Imuran (azathioprine) inorudzi rwema immunosuppressive antimetabolite drug. Imuran inogona kurongerwa kuti iite zvirwere zvakadai sekuputika kwechirwere chirwere (IBD) kana rheumatoid arthritis. Inogonawo kushandiswa muvarwere vane chirongwa chekugadziriswa kwechirongwa, kuitira kuti kudzivirira muviri kusaururwe nhengo. Izvi zvinoderedza hutachiona hwemuviri.
Muzviitiko zvizhinji, Imuran inoshandiswa kurapa IBD mushure mimwe mishonga isati yasashanda. Inogonawo kushandiswa panguva imwechete se steroids.
Mishonga inobatsira maitiro ezvirwere zvezvirwere zvinogona kuwedzera mukana wekudzivirira utachiona, uye kungwarira kungada kutorwa kunodzivirira kurwisana nezvirwere. Vanhu vanotora Imuran havafaniri kugamuchira chero zvirwere zvinorarama. Zvinogonawo kuva zvakakosha kudzivisa vanhu vanorwara uye chero chiratidzo chipi chekutapukirwa kunofanira kukurukurwa nachiremba pakarepo.
Black Box Warning
Mahwendefa eImuran ane bhokisi rakasvibiswa rinonyeverwa nehutano hwekugadzira imwe rudzi rwekenza. Izvi zvakabatana zvikurukuru kune vanhu vanotora mishonga uye vane IBD. Ngozi yekuve nekenza inofanira kuyerwa nehutano hwekusaporesa IBD nechirwere ichi.
Kanzera ngozi kune vanhu vane IBD ichiri nheyo inopfuurira yekukakavadzana nekudzidza, saka zvakakosha kutora nzira yakangwara paunofunga nezvengozi.
Dzimwe dzidzo dzakaratidza dambudziko, asi vamwe havana. Iva nechokwadi chekukurukurirana izvi zvinogona kukanganisa kuitika pamwe navanachiremba vako kuitira kuti iwe unzwisise dambudziko rako pachako.
Kurarama kwechirwere chisingaoneki neImuran, purine antimetabolite inowedzera ngozi yekuvhiringidza vanhu. Mishumo yezvakaipa zvinosanganisira post-transplant lymphoma uye hepatosplenic T-cell lymphoma (HSTCL) kune varwere vane chirwere chinoputika. Vanachiremba vanoshandisa ichi chirwere vanofanira kunge vakajaira zvikuru nezvengozi pamwe chete nehutano hwemutagenic kune varume nevakadzi uye pamwe nehematologic toxicities. Vanachiremba vanofanirwa kuzivisa varwere vengozi yekurwara neImuran.
Maitiro Akafanana Maitiro eImuran
Tarisa nechiremba wako kana chimwe chezvikamu zvinotevera zvinopfuurira kana zvinotambudza:
- kurasikirwa nechido
- kushungurudza kana kurutsa
Muchikamu Chisingabatanidzi Maitiro Akafanana Maitiro eImuran
Tarisa nechiremba wako kana chimwe chezvikamu zvinotevera zvinopfuurira kana zvinotambudza:
- Kushanda kweganda
Nguva dzose Ziva Chiremba
Zvimwe zvakajairika
- Chikoro, chinotyisa
- fever kana chills
- kuderedza shure kana kuti marwadzo
- kunorwadza kana kuoma kuoma
- kuneta kunoshamisa, kusava nesimba
Zvishoma Zvisingatauriki
- Dema, tarry mashizha
- ropa mumurini kana zvigaro
- Ita mavara matsvuku paganda
- kubuda ropa kunoshamisa kana kuputika
Zvisinganyanyi Kuwirirana Kana Zvakare
- Kutsamwa kwemoyo
- fever (kamwe-kamwe)
- musuru kana kurwadziwa
- kushungurudza, kurutsa, uye chirwere (chakanyanya)
- kubwinya kana blister paganda
- kukurumidza kufema
- maronda mumuromo, pamiromo
- dumbu kurwadziwa
- kupfugama kwetsoka kana kumakumbo makumbo
- kunzwa kusagadzikana kana kurwara (kamwe-kamwe)
Other Notes:
Chiremba wako achacherechedza zvinetso zvechiropa izvo zvinogona kuitika mishonga iyi.
Nemhaka yekuti nzira iyi yemishonga inoshanda mumuviri, pane mukana wekuti inogona kukonzera zvimwe zvinenge zvisingadiwi zvisingamboitike kusvikira mwedzi kana makore mushure mekunge mushonga uchishandiswa. Izvi zvinononoka migumisiro inogona kusanganisira mamwe marudzi ekenza, akadai sekemukemia, lymphoma, kana kenza yeganda. Ngozi yekenza yakaderera kune vanhu vanotora azathioprine yeArthritis, uye iwe unofanira kukurukura izvi zvinogona kuitika kune chiremba wako.
Mushure mokunge misa mishonga iyi, pane zvimwe zvingava nemimwe migumisiro. Panguva ino inozivisa chiremba wako nekukurumidza kana zvichibvira kana ukacherechedza chimwe chezvinotevera:
- dema, tarry zvigaro
- ropa mumuyo
- kugunun'una kana kumira
- fever kana chills
- kuderedza shure kana kuti marwadzo
- kunorwadza kana kuoma kuoma
- Ita mavara matsvuku paganda
- kubuda ropa kunoshamisa kana kuputika
Dzimwe mimwe migumisiro isina kunyorwa pamusoro apa inogonawo kuitika pane vamwe varwere. Kana ukacherechedza zvimwe zviitiko, tarisa nechiremba wako. Iyi ruzivo inongororwa semutungamiri - nguva dzose uongorore chiremba kana mhizimisi kuti uwane ruzivo rwakakwana pamusoro pemishonga yekurapa.
Kunobva:
Prometheus Laboratories Inc. " Imuran (azathioprin) Inotsanangura Mashoko ." FDA.gov. Feb 2014..
Armstrong RG, West J, Kadhi TR. "Njodzi yekenza mune zvirwere zvinoputira zvirwere zvinorapwa neAzathioprine: kuUnited States-based case-control study." Am J Gastroenterol . 2010 Jul; 105 (7): 1604-1609.