Uchapupu uye Kurwisana Kutora Probiotic yeCrohn's or Ulcerative Colitis
Maitiro e microbiome edu anokanganisa sei kubudirira kwehutachiona hwezvirwere (IBD) inyaya inopisa yekutaurirana nekutsvakurudza. Iyo microbiome inoreva zvose zvipembenene (mabhakitiriya uye microbes) zviri kurarama mumuviri wedu. Iyo microbiome yemukumbo mukuru kunyanya iri kuidzidzwa maererano nehosha yeCrohn uye chironda chekuonda kwehutachiona, nekuda kweshoko rokuti IBD inokonzerwa nokuvhiringidzwa kwe microbiome, kana kuti IBD inokonzera kukanganiswa.
Kuteerera kubva ipapo ndiko pfungwa yokuti kana microbiome inogona kugadziriswa, uye "kukodzera" kusanganiswa kwebhakitiriya kunogona kukurudzirwa mumugwagwa wezvokudya, izvo IBD inogona kugadziriswa kana kutorwa.
Pinda maitiro anonzi probiotics , ayo "ane ushamwari" mabhakitiriya anonyorerwa, zvichida nokuadya kana kutora muwedzere. Zvirongwa zveprobiotics zvinodhura, uye mukurumbira wavo uri kukura, asi ivo vanokoshesa mari yekutsinhanisa mari kana iri kuuya kuBD? Uye zvakatowedzera: Havasi kutongororwa neKudya uye Drug Administration, vachikwidza mubvunzo wekuti kana kwete vangakonzera kukuvadza.
Pfungwa dzinokosha kuti uchengete mupfungwa pamusoro pekushandisa maantibioti muBD:
- Izvo zvisati zvanyatsonzwisiswa kuti microbiome inobatwa sei neBD.
- Mamwe maitiro anonzi probiotics angave akashanda muBD, asi zvimwe zvinotsvakurudzwa zvinodiwa.
- Imwe nzira yekutengeserana inowanikwa mune zvekutengeserana yakaratidzwa ichishanda ye pouchitis kune vanhu vane j-chikwama.
- Probiotics inogona kudhura uye kunze kwekuti "kunaka" kushandiswa kushandiswa, hakugone kupa chero rubatsiro.
- Zvirongwa zveprobiotics zvinogona kuva zvinokuvadza kune vanhu vakave vasina simba rekudzivirira zvirwere zvezvirwere uye mucheche.
- Probiotic supplement inofanira kushandiswa pazano rechiremba.
Chii chinonzi Microbiome Sezvakanyorwa muBD Patients?
Iyo inozivikanwa kare kuti vanhu vane IBD vane maitiro akasiyana-siyana ezvisikwa mumugwagwa wavo wokudya kupfuura vanhu vane utano.
Iyo microbiome inonyanya kuenzaniswa: Munhu wose achava neyo pachake ye "yekare". Kunyange zvakadaro, kune maitiro mu microorganisms akawanikwa nevanhu vane IBD vakawanikwa nevatsvakurudzi. Izvi zvinoreva sei zviratidzo uye kurapa hazvizivikanwe. Saka, zvinonzwisisika kuti pane kuchinja mune microbiome yemunhu ane IBD asi hazvizivikanwe kuti izvi zvinokanganisa sei IBD uye kana ichi chimwe chinhu chinoda kurapwa kana chinogona kutarisirwa zvakanaka.
Maitiro Anonzi Probiotics Haabatsiri Here?
Pane pfungwa yokuti mapurobioti ose akanaka uye anodiwa uye kuti zvakanaka kuti "eedze" uye ona kuti inoshanda sei, nokuti hapana marwadzo. Muzviitiko zvakawanda, kunyanya kuvanhu vakuru vane utano hwakanaka, maitiro anonzi probiotics haafaniri kunge akaipa. Vanhu vazhinji vanodya probiotics mune zvokudya zvavo zuva nezuva, kunyanya mu yogurt, kombucha, kana kefir. Zvisinei, kune mamwe mapoka, akadai seavo vanorwara zvikuru, akaora simba rekudzivirira muviri, kana vacheche, somuenzaniso, maitiro anonzi probiotic anowedzera angaita kuti zvikuvadze. Hazvishamisi, asi migumisiro yakaipa yave ichitaridzwa, kunyanya mucheche dzinorwara dzakapiwa chirwere chebioti.
Sezvo tisati tisati taziva kuti zvipenyu zvipi kana kuti zvakadini zvazvo zvinodiwa kuti tishandure microbiome yedu nenzira yakanaka, kushandisa maprobiotics kuvanhu vanenge vatofa kana kuti vakwegura vangave vasina kuchengeteka.
Hapana humwe huchapupu hunokwana huripo hunobuda pane iyi neimwe nzira kana imwe, asi kubvumirana kukuru pane iyi ndechekuti maitiro eprobiotics haabatsiri, uye chiremba anofanira kubvunzurudzwa vasati vashandise.
Nzira Yokutaura Nayo Kana Probiotic Inoshanda
Kune vamwe vanhu, kutora probiotic kunogona kutanga kukonzera gesi uye kubvisa. Kutanga nehana yakaderera uye kuwedzera kwairi mberi kwenguva kunogona kubatsira kuderedza marudzi aya emigumisiro. Chero kushungurudzika kana zvimwe zvinetso zvinofanira kupera muvhiki kana maviri. Kana vasina kudaro, inguva yekudzokorora zvakare iyo probiotic ine chiremba. Zvinogona kunge zvakaoma kuziva kana chirwere chebibiro chiri kushanda.
Kune mumwe munhu ane zvipfeko zvisingaregi, kana chigaro chichisimudza icho chingava chizivo icho probiotic inoshanda. Asi kana IBD iri mukuregererwa , uye mapurobiotic ari kushandiswa kuramba ari munzira iyo: zvakaoma kuziva kana iri kushanda. Iyi ndeimwe yezvikonzero zvakawanda nei zvichikosha kukurukura probiotics ane chiremba uye kuchengeta diary yezviratidzo apo uchitanga maitiro emishonga.
Zvirongwa zvePirmi's Disease
Miedzo yeprobiotics muvanhu vakuru vane Crohn's disease mukuregererwa vakaratidza migumisiro yakavhenganiswa neprobiotic supplements, kunyange zvisinganzwisisi kuti matambudziko angabatsira sei. A meta-analysis (iyo apo vatsvakurudzi vanoverenga mitsva yezvidzidzo zvakasiyana-siyana kuitira kuti vasvike pakuguma) yezvipfumbamwe zvakadaro zvakaratidza kuti hakuna rubatsiro kune vanhu vane Crohn's disease. Ikoko kunogona kuva nekubatsirwa kunoonekwa apo michina yakawanda yakashandiswa pamwe chete, kunyanya Saccharomyces boulardii , Lactobacillus , uye VSL # 3 (iyo ibhizimisi rekutengeserana rine musanganiswa wemasere mabhakitiriya masere).
Paiva, zvisinei, miedzo mitatu yakabatanidzwa mune meta-analysis iyo yakaratidza "kubatsira kwakanyanya" kwevana vanorarama nechirwere cheCrohn vanowedzera nemaprobiotics. Izvo zvinofanira kuonekwa, zvisinei, kuti izvi zvaive miedzo, zvinoreva kuti vana vakanga vari pasi pekutarisirwa kwachiremba, kugamuchira kuongorora kwakanyanya, uye kuti maitiro ebioti haafaniri kushandiswa mune vana vane IBD pasina kukurukura nachiremba.
Probiotics in Ulcerative Colitis
A meta-analysis iyo yakatarisa miedzo 18 yemaprobiotics kune varwere vanorarama nechirwere chepachirwere yakagumisa kuti pane "zvakakosha." Vatsvakurudzi vakaona kuti mazana emaprobibio akaratidzwa kuti anoshanda zvakanyanya kune vanhu vane ulcerative colitis. Kuwedzera pamwe neLactobacillus probiotic uye prebiotics kwaive nekubudirira muhutachi inouraya asi kwete muCrohn's disease. Iko kushambadzira kwevatengesi VSL # 3 kwakaratidzwa kuva yakagadzirisa chironda chekurara, uye kana ichibatanidzwa neCactobacillus, yakaratidzwawo kuti ine simba kune vana vane IBD. Zvakare, zvinofanira kuonekwa, kuti kushandiswa kwemaprobiotics kuvanhu vane IBD kunofanira kuitwa pasi pekutarisirwa kwechiremba, kunyanya panyaya yevana vane chirwere.
Probiotics yeJ-pouches
Kune boka rimwe revanhu vane IBD iyo maitiro anonzi probiotics ave akaratidzwa anoshanda, uye ndivo vanhu vane j-pouch. Kuvhiya kweJ-pouch chiratidzo chekuvhiya chakaitirwa vanhu vane ulcerative colitis, uye izwi rezvesayenzi ndiro ileal pouch-anal anastomosis (IPAA). Munguva yekuvhiya iyi, ikoni inobviswa, pamwechete nechikamu kana yese rectum. Chikamu chekupedzisira chemukati madiki chinogadzirwa muhomwe iyo inotora nzvimbo ye rectum uye inonamirwa kune anus.
Imwe ingangodaro kusangana kwe j-pouch ndiyo inonzi pouchitis , iyo inounza zviratidzo zvehuvha, fever, kukurumidza, uye dzimwe nguva zvigaro zveropa. Pouchitis haina kunzwisiswa, asi kune humwe humwe uchapupu hwokuti kushandiswa nguva dzose kweprobiotics kunogona kubatsira kudzivirira zvinyorwa zve pouchitis. Rimwe dambudziko reprobiotics, iro rakagadzirwa uye rakagadzirwa nekambani imwe chete, rakadzidzwa uye mhinduro dzinoratidza kuti dzinogona kubatsira kudzivirira pouchitis kana kuchengeta murwere mukuregererwa mushure mekupitis yakarapwa nemishonga inorwisa mabhakitiriya. Izvo zvinokanganisa ndezvokuti probiotics inodhura uye haigoni kuvharwa nehushuwarisi nekuti inofanirwa sekuwedzera uye kwete mishonga.
Will Probiotics Vachava "Mushonga" weBD?
Nepo kune zvimwe zvidzidzo zvinoratidza kubatsirwa kwekutora mamwe marudzi emishonga inonzi probiotics kune dzimwe sendipi dzeBD, mamiriro acho haazove akakosha zvakakwana kuti aonekwe sechirapa. Zvirongwa zvebioti zvinogona kubatsira vamwe vanhu vane IBD, asi zvakakosha kucherechedza kuti havazogoni zvakakwana kuti varwere vanokwanisa kurega kutora mishonga yeBD.
Shoko Rinobva
Kushandiswa kweprobiotics kuporesa IBD inotaridzika. Zvisinei, kuchine mibvunzo yakawanda inofanira kupindurwa, kunyanya iyo iyo microbiome inobatwa sei kutanga kweBD uye kuti inoshanduka sei apo IBD iri kupisa uye iyo iri mukuregererwa. Kune matambudziko akawanda akasiyana-siyana emakiromita mumugwagwa wezvokudya kuti zvakaoma kuziva kuti mabhakitiriya anofanira kushandiswa kuchinja chiyero. Vatsvakurudzi vari kuzvikudza pamusoro pematambudziko api angave anobatsira, asi kune zvimwe zvisingazivikanwi kupfuura izvo zvinozivikanwa munzvimbo ino. Kusvikira pane zvimwe zvitsvakurudzo zvekutsvaga, hazvisi pachena asi ndiani angabatsirwa neprobiotic supplement. Zvichida kana kuti kwete chirwere chinonzi probiotic chinofanira kushandiswa ndechekukurukurirana kunofanira kuitika pakati pechiremba nemurwere nekuti ichisarudzo chega. Pane "kuedza uye kuona," chiremba anogona kupa humwe hutungamiri hwemakemikari ebhakitiriya angabatsira.
> Sources:
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> Gionchetti P, Calabrese C, Lauri A, Rizzello F. "Kugona kurapa kwemishonga inorwisa mabhakitiriya nemaprobiotics mukurapwa kwe pouchitis." Nyanzvi Rev Gastroenterol Hepatol . 2015; 9: 1175-1181.
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