MTHFR Gene uye TRPV1 Gene iyo Inobatsira kuMigraines
Kana iwe uchitambura nekukanganisa migraines, kune mukanano wakanaka kuti hanzvadzi yako, cousin, kana amai vanoitawo saizvozvo. Izvi ndechokuti majini ako anokuita kuti uwedzere kunetseka kukura migraines.
Ngatitsvakei genetics ye migraines uye kuti izvi zvinorevei iwe nemhuri yako.
Kukurukurirana pakati peGenesis uye Zvakatipoteredza mumusoro
Ruzhinji rwemusoro runokonzerwa nehuwandu hwemashoko ehutachiona uye hwezvakatipoteredza huri kuwirirana muwebhu yakaoma.
Kunyange zvazvo vazhinji venyu vari kushanda musingagumi mukudzora zvakatipoteredza kuburikidza nekudzivirira kutadza uye kuchinja maitiro, iwe pachena haugone kuchinja majena awakaberekerwa nawo. Zvisinei, kuburikidza nekudzidza inonzi genetics inobatanidzwa mune migraine kutanga, vasayendisiti vanogona kugadzira mishonga mitsva inotarisa mamwe majini, mune tarisiro yekurapa, kana kusaderedza misoro yedu inoremedza uye inoparadza.
Ndeapi marudzi eGenesis anowanikwa mumigraines?
Pane basa rinokosha renhaka mukugadzirisa migraines uye mamwe musoro musoro . Izvi zvakaratidzwa kuburikidza nemhuri dzakawanda uye mapatya maviri. Asi ndeapi mahedheni chaiwo ari kupera? Pasi pane muenzaniso wemajini maviri anofungidzirwa kuti inobatsira pakuumbwa kwemigraines.
Rimwe geni rinonzi MTHFR gene , iyo inomirira kwenguva refu, methylenetetrahydrofolate reductase. Iyi geni inobatanidzwa mumugwagwa wa homocysteine. Homocysteine is an amino acid muropa redu iro kana rakasimudzwa, rinogona kutungamirira kuropa rekuvhiringidza kweropa, pamwe nekuputika kwemamwe masero emasero angave akabatanidzwa mumusoro.
Zvimwe zviitiko zvegene iri zvakabatanidzwa nezvose migraines nemasumbu emusoro .
Chimwe chekudzidza mu Pharmacogenetics uye Genomics chakaona kuti kuvakadzi vane migraine vane aura , vitamin supplementation zvakaderedza zvikuru maitiro avo e homocysteine, migraine zvakasimba, uye migraine kuremara, zvichienzaniswa nevakadzi vakatora placebo.
Vitamin supplementation yakaitwa ne vitamini B6, B9 (folic acid), uye B12, iyo yakawanikwa ichideredza maitiro e homocysteine muropa.
Uyezve, apo boka revaritamini rinotariswa rakaongororwa zvakanyatsonaka, zvakaonekwa kuti varwere vane ruzivo rwakakwana rweMTHFR gene vaiva nekuderedza kukuru pane homocysteine mazinga, uyewo migraine kuoma uye kuremara kwezvikwata, kune avo vane nzvimbo dzakasiyana-siyana . Chimwe chikamu ndechimwe chimiro chejeni ine nzvimbo chaiyo pane imwe chromosome. Izvi zvinoratidza kuti zvimwe zvipembenene zvegene zvinogona kukanganisa maitiro akanaka emagraineurs anopindura mavitamini supplementation.
TRPV1 (Zuva Rinoenderana Nezvimwe Zvimwe Zvinokonzera Vanilloid Rudzi rwa 1) rwakarongedzwa kuti ritambe basa rinokosha mukugadzirisa migraine - izwi rinoreva kushungurudzika kwepamusoro kana kusagadzikana kwehutachiona hwevarwere vane migraines.
Iyi geni inobatsira mune migraine hyperalgesia uye allodynia , zviitiko zviviri zvinogona kuitika panguva yekurwisana kwemasimba. Hyperalgesia inoreva kuwedzera kwekuita kune chinorwadza chinorwadza. Allodynia inoreva kupindura kunorwadza kune zvinowanzosavhiringidza zvisingakuvadzi, zvakadai sekunzwa kusagadzikana nekubata nyore panguva yekurwiswa kwemasimba.
Mumakore mashomanana apfuura, zvinodhaka zvinotarisana nemitambo yeTP zvakadzidzwa sevangashandisa migraine mishonga.
Mumwe muenzaniso wechirwere chinoshandiswa neTTRPV chiteshi ndeye sumatriptan , iyo inowanzobatwa nemishonga inonzi migraine therapy.
Izvi Zvinorevei Kwandiri?
Mufananidzo mukuru pano ndewokuti migraine ine simba rakakura remarita. Nokudzidza zvakawanda pamusoro pemamwe majini anowanzoita kuti munhu aite migraine, masayendisiti anokwanisa kutsvaga zvinodhaka kune majeni aya.
Uyewo, kunzwisisa nheyo dzemaitiro emigraine kunogona kubvisa chimwe chetoro vanhu vanoona, sezvavanoedza kudzora migraine yavo kurwisa. Funga kukurukura nezvehupenyu hwemhuri yako nemupi wako wehutano, sezvo izvi zvinogona kupa ruzivo rwemigraines yako uye hune simba mune ramangwana rerapi.
Sources:
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