Zvingave Zvakadiiwa Zvine Mhuka Zvingave Zvirongwa Zvokurapa KweBD?
Fecal bacteriotherapy (FB) kana kuti fecal microbiota transplantation (FMT) chirwere chechirwere chakashandiswa kwemakore mazhinji, asi ikozvino chinotanga kuongororwa nokuda kwekushandiswa kwaro mune chirwere chinoputika (IBD) . FB dzimwe nguva inoshandiswa kurapa zvirwere zvinowanzoitika neClostridium difficile (kana kuti C difficile ), kunyange izvi zvisingawanzoitiki.
Izwi Rine Simba Rokuchenjerera
Fecal transplants haafaniri kuitwa kumba , kunyange pashure pokuverenga mirayiridzo kana bhuku kana kutarisa vhidhiyo yekuti ungazviita sei.
Haisi iyo "sei" kuita icho icho chikamu chakaoma. Chikamu icho chiri chichiri kuongororwa ndicho chinoita kuti munhu anopa mupiro akanaka uye kuti uyo anopa sei mugadziri mabhakitiriya achabatana uye achishandura gadziriro yemagakitiriya. Varwere vafa mushure mekushandisa "do-it-yourself" fecal transplants. Vamwe vakaona zviitiko zvisingadikanwi zvakadai sezvirwere zvitsva zvemuviri kana kuti kuwedzera kuwedzera. Ichi chirapa ichichiri kuongororwa nevanhu vane IBD uye hachisi chinhu chimwe chinofanira kuitwa kumba.
Fecal Bacteriotherapy For C Difficile
Utumbo hukuru huri nemhando dzakasiyana siyana dzebhakitiriya. Iyo yakagadzirwa kana nhamba yemhando dzakasiyana dzemabhakitiriya inogona kuchinjwa nechirwere kana nemishonga. Utachiona hweC difficile hunogona kuitika apo bhakitiriya maruva mumatumbo makuru akashandurwa (kazhinji nemishonga inorwisa mabhakitiriya), zvichibvumira C difficile kuwedzera uye kubudisa chepfu, iyo inogona kukonzera kukanganisa uye kutyisa upenyu hwehutachiona uye chirwere.
Iko kunowanikwa kwehutachiona hweC difficile ndeyezuva 10 kusvika ku14 remazuva e anti- C difficile antibiotics. Dzimwe nguva, C difficile colitis inogona kudzoka shure kwekurapa kwapera. Izvi ndezvezviitiko izvi zvinopesana kuti FB yakwezva kunyanya kutarisa.
FB inotanga kurapwa iyo isati yashandiswa kana kuti yakadzidza zvakanyanya, asi yakamboedzwa mune vamwe vanhu vane zvirwere zvekare zveC difficile .
Iyo nzira inotanga nehama yepedyo yemurwere uyo anoda kuunganidza chigaro chavo kwemazuva mashomanana ndokuipa. Nyaya yechipfuva inoedzwa chero chipi zvacho chinogona kuratidza kukuvadza - sechirwere, mabhakitiriya emunyika kana maharasi . Mushure mokunge chigaro chacho chichatsunga kuchengetedzwa kuti chigadziriswe, chinogona kushandiswa kuFB.
Kuti Fecal Bacteriotherapy Yakaitwa Sei
Izvo zvipfeko zvinogona kuendeswa mumurwere kuburikidza ne enema , colonoscopy kana kuti nasogastric (NG) tube . Kana yakapiwa neemaema, nyaya yefecal ingangosanganiswa nemvura, yakadai sa saline, uye inopiwa kana chiremba, kana kumba kumba komunhu kana murwere pachake. Anemaema inongowedzera kusvika kumakoloni, saka kutungamirira kudhindwa kuburikidza nekolonoscopy imwe nzira inoshandiswa. Apo nzira yacho inopedzwa kuburikidza nekolonoscope, nyaya yefecal inogona kupararira mukati mekoloni, iyo inofungidzirwa kuti inobudirira. Apo iyo tube NG (iyo inowanikwa nenzira yakajairika) inoshandiswa, maronda anokwanisika anogona kugoverwa mukati mechidiki duku uyewo yose mumukaka mukuru. A proton-pump inhibitor inowanzopiwa panguva imwe chete kuitira kudzivirira mabhakitiriya anobatsira kubva pakuurayiwa nemudumbu acids.
Fecal Bacteriotherapy KwaBD
Imwe yedzidziso pamusoro pezvikonzero zvinokonzerwa neBD zvinosanganisira kuchinja kwebhakitiriya maruva mumukati mukuru. Inofungidzirwa kuti kana vanhu vane IBD vasina kushaya mamwe mabhakitiriya mumakoloni, kana kuti akawanda kwazvo, FB inogona kuva yakakosha kurapwa. FB yakangotsvakurudzwa kuti ishandiswe muBD mune zvimwe zvidzidzo, zvidzidzo zvepakutanga, kuitira kuti kubudirira kusati kuchiratidzwa. Chimwe chinetseka pamusoro pekushandiswa kweFB ndiko kuda kwevanhu vane IBD kuti vaite izvi. Vamwe vatsvakurudzi vakaita tsvakurudzo shoma kuti vaone kana vanhu vane ulcerative colitis vaizofunga FB, uye pfungwa yacho yakazogamuchirwa zvakanaka.
Uyewo Anozivikanwa Se: fecal microbiota transplantation (FMT)
Sources:
Kahn SA, Gorawara-Bhat R, Rubin DT. "Fecal bacteriotherapy nokuda kwekuonda kwehutachiona: Varwere vakagadzirira, isu isu?" Inflamm Bowel Dis 25 May 2011 DOI: 10.1002 / ibd.21775. 31 Jul 2013.
Anoshayiwa TJ, Warren EF, Leis S, Surace R, Ashman O. "Kurapa kwechirwere chepachilwere uchishandisa bacteriotherapy fecal". J Clinic Gastroenterol 2003 Jul; 37: 42-47. 31 Jul 2013.