Dambudziko reBongo rinosviba rakaipa kupfuura nguva
Chiitiko cheCreutzfeldt-Jakob chakaitwa mumusoro wegore ra2000 apo kukwira kwematambudziko kwakabuda muUnited Kingdom. Izvo zviitiko zvakabatanidzwa nezvokudya zvakasvibiswa nehavha spongiform encephalopathy (BSE), chirwere chepachion chinokonzera CJD yakasiyana, iyo inozivikanwa se "chirwere chemhou".
Vanhu vose vane chikonzero chakanaka chokufunganya pamusoro pekuendeswa kweBSE kuvanhu.
Kusiyana kwechirwere cheCreutzfeldt-Jakob, kufanana nedzimwe mhando dzechirwere cheCreutzfeldt-Jakob , iri kufambira mberi nokukurumidza, nguva dzose inouraya chirwere chepfungwa. Asi chirwere chacho hachiwanzoitiki: Kubva munaOctober 1996 kusvika munaMarch 2011, 175 chete mhosva dzevCJD dzakaparidzwa muUnited Kingdom, 25 muFrance, 5 muSpain, 4 muIreland, 3 muNetherlands uye United States of America ( USA), 2 imwe neimwe muCanada, Italy nePortugal, uye imwe neimwe muJapan, Saudi Arabia neTaiwan.
ICentral for Disease Control and Prevention (CDC) inotarisa zvinoitika muUnited States zvemarudzi ose eCreutzfeldt-Jakob chirwere.
Mhando dzakasiyana dzezvirwere, nguva dzose dzinouraya
Hakuchina mushonga weCreutzfeldt-Jakob chirwere, chinogona kuitika mumunhu mune imwe yenzira zvitatu:
- Inenge 10 kusvika ku15 muzana yematambudziko inotora nhaka, inokonzerwa nejen mutation.
- Zviitiko zvizhinji zvinoratidzika sezviri kuonekwa zvishoma nezvishoma, kune mumwe munhu asina mhuri yezvechirwere ichi.
- Chikamu chiduku chezviitiko zvinowanikwa kuburikidza nehutachiona, nekubatana nehutachiona hwehutachiona hutachiona. Iko kune zviitiko zvakanyorwa zvakangoitika sechikonzero chisingadikanwi chekurapa.
Chirwere cheCreutzfeldt-Jakob hachina kupararira nenzira dzakasununguka, sekunyunyuta kana kukoromora - hapana maziviro anozivikanwa evakaroorana kana nhengo dzemhuri dzevanhu vane hutachiwana vanotapira chirwere chacho.
Nyuchi Dzakasvibiswa Nenyama
Mamiriro ezvimwe zvirwere zveCreutzzeldt-Jakob anoita seanobatanidzwa nekudya zvinhu zvakasvibiswa zvekudya muEurope. Chirwere ichocho, kana chinoitika mumakwai, chinonzi "scrapie." Zvinofungidzirwa kuti zvipembenene zvinotapukirwa nemakwai zvakashandiswa mumombe yekudyisa, uye ndizvo zvakaita mhuka dzakapinda.
Masayendisiti akawana kuti chii chinokonzera BSE, scrapie, uye zvirwere zveCreutzfeldt-Jakob haisi hutachiona kana mabhakitiriya semamwe zvirwere, asi chirongwa cheprotein chinonzi prion. Iyo yekutanga inoshandura mapuroteni anowanzopindira mune zvinotapukira, zvinouraya.
Migumisiro paBongo
Sezvo chirwere cheCreutzfeldt-Jakob chinokanganisa uropi, zviratidzo zvaunobereka ndezvehutano. Zvinogona kutanga zvinyengeri nekushaya hope, kuora mwoyo, kuvhiringidzika, unhu uye hutsika hunochinja, uye zvinetso nekuyeuka, kubatana, nekuona. Sezvo ichifambira mberi, munhu wacho anokurumidza kukura chirwere chekuita nehutano uye kusazvipira, kushambadzira kusina kukodzera kunonzi myoclonus.
Muchikamu chekupedzisira chechirwere, murwere anorasikirwa nemabasa ose epfungwa uye mumuviri, anopera mu coma, uye pakupedzisira anofa. Chikoro chechirwere chinowanzotora gore rimwechete. Chirwere ichi chinowanzobata vanhu vari pakati pemakore makumi mashanu kusvika ku75, zvisinei, zvirwere zvakasiyana-siyana zveCreutzzeldt-Jakob zvirwere zvakakanganisa vanhu vari vaduku - kunyange vachiri kuyaruka (makore ava nemakore gumi nemasere kusvika makumi mashanu).
Zvakaoma Kuongorora
Hakusi, kunyange zvakadaro, chirongwa chechirwere chechirwere chekuongorora chirwere cheCreutzfeldt-Jakob, uye kusimbiswa kwechirwere kunogona kungoitwa chete mushure mekufa kuburikidza nehutachiona. Sezvo chirwere chacho chisingawanzoitiki, vamwe vanachiremba vangave vasingatombozvifungi sechirwere uye vanogona kukanganisa zviratidzo zvehumwe zvirwere zvehupfungwa zvakadai seAlzheimer's kana kuti Huntington chirwere . Masayendisiti anoratidza kuti itsva, yakanyatsoongorora ma laboratory inotarisirwa munguva yemberi ichakwanisa kuona mhemberero muropa romunhu ane hutachiwana kana mishonga.
Sources:
Collins, S., A. Boyd, A. Fletcher, MF Gonzales, CA McLean, CL Masters. "Kufambira mberi munguva pfupi muhutano husati hwafa hunoongorora chirwere cheCreutzfeldt-Jakob." J Clin Neurosci 7 (2000): 195-202.
"vCJD (Chimiro cheCreutzfeldt-Jakob Disease)." NCIDOD. 29 Nov 2006. Nzvimbo dzeChirwere nekudzivirira zvirwere. 28 Dec 2006 http://www.cdc.gov/ncidod/dvrd/vcjd.
Will, R., M. Zeidler, GE Steward, MA Macleod, JW Ironside, SN Cousens, J. Mackenzie, K. Estibeiro, AJ Green, R. Knight. "Kuongororwa kwechimwe chitsva cheCreutzfeldt-Jakob chirwere." Ann Neurol 47 (2000): 575-582.
Wilson, K., C. Code, M. Ricketts. "Ngozi yekuwana chirwere chaCreutzfeldt-Jakob kubva pakuwedzerwa ropa: Kuongorora kwakarongeka kweongororo yekuongorora." BMJ 321 (2000): 17-19.