Lipoprotein (a), inozivikanwawo seLp (a), inonzi low-density lipoprotein (LDL, kana kuti "yakaipa" cholesterol) ine imwe mhando yeprotini, inonzi glycoprotein, yakabatanidzwa nayo. (Zita iri glycoprotein apolipoprotein (a). )
Vatsvakurudzi vachiri kushanda kuti vanzwisise lipoprotein (a) uye nzira dzingakanganisa utano hwako. Zvisinei, zvimwe zvidzidzo zvinoratidza kuti kuva nehupamhi hwe lipoprotein (a) kupararira muropa rako kunogona kukuisa pangozi yakakura yekuvandudza chirwere chemwoyo .
Iko Lipoprotein (a) Ano
Yakagadzirwa muropa rako uye iyo inopinda muropa rako, lipoprotein (a) yakaratidzwa kuti ivakwe pasi pemukati wechipfuva wemariti. Izvi zvinogona kuita kuti kukura kwe atherosclerosis-inoenderana nemafuta emapurisa mumaketani ako anogona kutungamirira kuhutano hwemoyo, kurwisa kwemwoyo, nekurova-nekusimudzira kuputika kweputi (kubwinya nekudzimba) nekuumbwa kwemafupa emasero, mafuta masero anonamatira atherosclerotic plaques Pamusoro pe:
- Musoro wepopoprotein (a) inofungidzirwa kuti inonyanya kukuvadza kuronga masvingo kana munhu weLDL ("bad") cholesterol zvakare akakwirira.
- Higher lipoprotein (a) mazinga akaratidzirwa kuderedza mikana yekupona mumunhu ane chirwere chemwoyo.
Nhamba Dzose
Kuongororwa kweRopa kune mazinga e lipoprotein (a) anotsanangurwa mumamiriyoni kuburikidza ne deciliter (mg / dL). Nhamba ye 30 mg / dL inoonekwa seyakanaka. Zviwanikwa zvakapfuura 30 mg / dL zvingaratidza kuti 2 kusvika ku3-yakawanda inowedzera ngozi yepfungwa yemwoyo.
Zvisinei, lipoprotein (a) mazinga haasi chikamu chepurogiramu yepamusoro yeropa rekuongorora ropa, iyo inoyera mazinga ezviyoti cholesterol , LDL, uye HDL cholesterol, uye triglycerides (mafuta emufuta anowanikwa mumuviri wose). Izvi zvinokonzerwa nokuti 1) hazvina kukwana inozivikanwa nezve lipoprotein (a) 's effect pamwoyo yehutano uye 2) inowanikwa mune 15% chete yevanhu vakawanda, nevanhu vasiri sepanosipamende Caucasian, chiChinese, uye chiJapane chinotsika mazinga.
Izvozvo zvakati, pane mamiriro mashomanana apo zvingave zvakanakisisa kuti nguva dzose uone lipoprotein (a) mazinga. Kunyanya, izvi ndezvipi apo munhu ane:
- Chirwere chepfungwa chinowanikwa uye maitiro akaenzana eHDL, LDL, uye triglycerides
- Imwe mhuri yakasimba yehutano hwemwoyo asi, zvakare, yakajairika HDL, LDL, uye triglyceride mazinga
- Kuenderera mberi kwepamusoro kweLDL mazinga pasinei nekuwana utsinye
Unofanira Kuedza Kuderedza Nharaunda Yako Here?
Zvinosuruvarisa, nokuti lipoprotein (a) mazinga anonyanya kutungamirirwa nemajeni ako, zvinowanzogadziriswa-kudya kwakanaka, kugara uchirovedza muviri, uye (akawanda) cholesterol-kuderedza mishonga- hauna basa rakawanda pakudzikisa. Niacin akaratidza chimwe chivimbiso mune zvidzidzo zvekliniki yekuderedza lipoprotein (a) mazinga. Zvisinei, haisi kushandiswa nguva dzose nekuda kwechinangwa ichocho.
Kana uri kuedza kuderedza dambudziko rako rekudzivirira chirwere chemwoyo, zvakanakisisa kuisa lipoprotein (a) pakurapa "kudzorera kutsva" kwezvino uye kuisa pfungwa pane nzira dzekudzikisa zvakagadziriswa zvinokonzerwa nechirwere chemwoyo. Sezvo zvichida unoziva, izvi zvinosanganisira kuderedza ropa rako kana rakanyanya kukwirira, richideredza high LDL cholesterol, nekusimudzira pasi HDL cholesterol. Ongororo dzakawanda dzakaratidza kuti kutarisa zvinhu izvi zvinogona kuisa njodzi kunogona kuderedza dambudziko rako rekushaya chirwere chemwoyo kana kurohwa.
Sources:
Erquo S, Kaptoge S, Perry PL et al. Lipoprotein (a) kukanganisa uye njodzi yechironary heart disease, chirwere, uye zvisingaiti. JAMA 2009; 302: 412-423.
Boffa MB, Koschinsky ML, Berglund L. Lipoprotein (a): chimwe chinhu chinokonzerwa nehutano hwehutano hwemwoyo. Clin Lab Med 2006; 26: 751-772.
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Kang S. "Chii chinonzi lipoprotein (a) uye zvinorevei kwauri?" HealthCentral (2008).