Iyo inozivikanwawo se-subarachnoid space, nzvimbo inonzi intrathecal inzvimbo yakazara-yakazara inenge iri pakati pepakati mukati-kati chekufukidzira (iyowo yakamera) yomutsara wepelinha uye nechepakati pekufukidzira (arachnoid mater).
Yakagadzirirwa Inrathecal Drug-Delivery Systems (IDDSs)
Nzvimbo inonzi intrathecal inogona kushanda semugwagwa wekutungamirirwa kwezvinodhaka zvinoshandiswa mukugadzirisa kurapwa kwekurwadziwa.
Somuenzaniso, kuiswa mishonga yemishonga , inozivikanwawo semapumpu emarwadzo kana morphine pump, shandisa nzira iyi.
Kugovera mishonga inorwadza munzvimbo inopindira pane nzvimbo yekutora mapiritsi zvinyorwa zvinodikanwa kuti muviri upfuure uye uwane mishonga. Izvi zvinowanzoshandura muhutano huri nani huri nani nemaduku maduku. Nokuda kwechikonzero ichi, mujenya wemishonga inorwadza munharaunda inopindira inogona kukupa ruzivo rwakawanda rwekurwadziwa kana tichienzaniswa nemamwe mishonga kune vanhu vane kurwadziwa kukuru, kusingagumi. Ichowo chisarudzo chisingaperi chekusangana nekurwadziwa kusingaperi. Mune mamwe mazwi, kana iwe uchiedza uye usingafariri, kana iwe ukasarudza pane nzira yakasiyana yekurapa, haufaniri kuramba uchiita - iyo pombi inogona kubviswa nyore nyore.
Kushandiswa kwezvinodhaka zvinoshandiswa pakushandisa zvinodhaka zvinogona kupiwa kwauri nechiremba wako ane kurwadziwa kana iwe uine nguva refu, kurwadziwa kwakanyanya uye wakamboedza mhando dzakawanda dzekuchengetedza (kureva,, kwete-invasive kana kuti kwete-chirurgic) zvishoma nezvishoma muzviratidzo zvako.
Maererano naGhafoor, Epshteyn, Carlson, Terhaar, Charry, naPhelps munyaya yavo, "Inrathecal drug for long-term management management," yakabudiswa mumagazini yaDecember 2007 yeAmerican Journal of Health System Pharmacy , pane kushayikwa wehumwe humwe uchapupu hwokutsigira kushandiswa kwekushandisa kwekushandisa zvinodhaka zvinokonzerwa nemaitiro asinganzwisisiki, anorongedzwa kliniki.
(Randomized controlled clinic trials is a high-quality type of medical research study that compares one treatment with another treatment, no treatment or sham treatment.)
Ghafoor, et. Al anotaurawo kuti nokuti akawanda emishonga inoshandiswa mumapumpu emishonga epamusoro haana kuwanika pamusika, inofanirwa kuenzaniswa nevafarisi. Mishonga yakadaro inosanganisira: Opioids , anesthetics yemo, clonidine, baclofen, uye ziconotide, vanoti.
Vatsvakurudzi vanowedzera kuti vanachiremba ndivo vanokosha muhutano hwehutano hwekushandiswa kwezvinodhaka kwemishonga nokuti vanobatanidzwa mune zvakawanda zvekugadzirisa - kubva mukufungidzira uye kuedza kuisa zvinetso kune varwere vane njodzi, kumabhuku, kuongorora nekuraira, uye kuwedzera mishonga.
Ngozi dzeMishonga Inodhaka
Kunyange zvazvo pombi iyo inopa mishonga muchivako chinonzi intrathecal inobatsira vanhu vazhinji kuderedza marwadzo avo nekudzorera upenyu hwavo, iyo nzira inouya nezviitiko zvishoma. Kufungidzira, mugadziri wezvinodhaka zvemishonga urusi hutachiona, maronda emusana wemvura, uye misoro sematatu makuru. Kusashanda kwechigadzirwa chimwe chinhu chinogona kuisa njodzi, vanoti.
> Kwakabva:
> Ghafoor VL, Epshteyn M, Carlson G., Terhaar D., Charry O., Phelps P. Intrathecal Drug Therapy yekutora nguva refu. Am J Healthy Pharm. Dec 2007.
> Makomborero uye Njodzi - Mapumisi emishonga. Chronic Pain. Medtronic.