Inhaled hypertonic saline imwe yezvitsva zvinoshandiswa pakushandiswa kwe cystic fibrosis (CF). Boka revatsvakurudzi veAustralia vakawana kubatsirwa kwe hypertonic saline pavakaona kuti vanofambisa neCF vaiva nemigumisiro iri nani kune vanhu vane CF vasina kushanya. Vatsvakurudzi vaifunga kuti kubvongodza mhepo ine mvura yegungwa panguva yekufambisa kwaiva chikonzero chokuti vafambisi vainge vasina zvishoma zvokuputira kunze kwevamwe vavo vakanga vasingatendi, uye chidzidzo chakasimbisa izvo zvakawanikwa.
Vatsvakurudzi vakabudisa mhinduro dzekudzidza kwavo muna 2006, uye kubva ipapo, hypertonic saline yakange iripo sekurapa kwavanhu vazhinji vane CF.
Chii chinonzi Hypertonic Saline?
Kazhinji saline inogadziriswa nemvura yemunyu inenge yakafanana yemunyu semuviri wedu wemvura. Hypertonic saline iyi inogadzirisa mvura yemunyu inenge iine huwandu hwemunyu kupfuura inowanzoita saline, uye naizvozvo yakawanda yemunyu kupfuura muviri wemvura. Kazhinji saline solution ndiyo 0.9% munyu. Iyo hypertonic saline inoshandiswa muCF yakarapwa inomwe 7% munyu.
Hypertonic saline inopiwa kuvanhu vane cystic fibrosis kaviri zuva rimwe nerimwe.
Iyo Inoshanda Sei
Zviratidzo zvinopinda mukati uye kunze kwemasero nemushandisirwo unonzi osmosis , uko mvura ine mvura yakadzika yemunyu inoyerera ichienda kune imwe membrane yesero kunosanganiswa nemvura inopisa nemugariro wakanyanya wemunyu. Zvichitaura zvisinganzwisisiki, musmosis zvinoreva kuti mvura inotevera munyu.
Muchirwere cheCF, mhepo inonzi nebulizer aerosolizes hypertonic saline solution. Mhepo inonzi saline inoputika uye inogara mumhepo. Nemhaka yokuti hypertonic saline ine huru yakawanda yemunyu pane yakasvibirira yemvura, inobudisa mvura kubva mumasero kuenda kunzira. Mvura inovhengana nehombe yakakura mumugwagwa, ichiita kuti ive yakaonda uye nyore nyore kubuda kunze kana expectorate.
(Expectorate ndiyo chirwere chekurapa kwekukandira kunze kwemukoko.)
Kutsvakurudza kuongorora kushandiswa kwe hypertonic saline kune vanhu vane cystic fibrosis inoratidza kuti kurapwa uku kungaguma nekuvandudza kuduku mumapurmonary basa uye zvishomanana kurwisa kana kuwedzera. Kunyange zvakadaro, mishonga yechipatara yakasiyana pakati pevanhu, uye vamwe vanhu vanogona kuwana ruyamuro rwakawanda kupfuura rwevamwe.
Migumisiro yakaipa
Hypertonic saline haisi mishonga, asi inokonzera kuchinja mumuviri unogona kuva nezvimwe zvisingafadzi. Vamwe vanhu vanoshandisa hypertonic saline vakaona kuwedzera mukukanganiswa, kurwadziwa kwehuro kana kurwadziwa kwepfupa kunokonzerwa nehutu hunotyisa.
Haasi Saline Mvura Yomunyu Here? Inogona Kuitwa Pamba Here?
Aiwa. Mhedziso yemunyu inofanira kunge yakajeka, uye izvi zvingava zvakaoma kuita mumagadzirirwo emagetsi. Chinonyanya kukosha, mhinduro yacho inofanira kuva yakaoma kudzivirira kuunza mabhakitiriya anokwanisa kuuraya mumhepo.
Sources:
> Chesnutt MS, Prendergast TJ. Kugadzikana kwepulmonary. Mu: Papadakis MA, McPhee SJ, Rabow MW. eds. Kurapa Kwazvino Kwemishonga uye Kurapa 2016 . New York, NY: McGraw-Hill; 2016.
Donaldson, SH, et al. "Mucus Clearance uye Mhemberero MuCystic Fibrosis neHypertonic Saline". 2006. New England Journal of Medicine 354 (3): 1848-1851. 4 August 2008.