Statins inowanzoshandiswa kurapa high LDL cholesterol mazinga . Vanoderedza cholesterol inogadzirwa muchiropa nekudzivisa chimwe chinhu mumugwagwa we mevalonate. Chimwe chinhu chisina kunaka chemasimita ndechekuti vane simba rekukonzera kuora kwechiropa. Chimwe chinhu chinogutsa ndechokuti vanogona kuderedza dambudziko remunhu wekuita kenza yemukironi .
Mienzaniso Yezvinyorwa
Mienzaniso yemitemo inosanganisira Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Pravachol (pravastatin), Crestor (rosuvastatin), uye Zocor (simvastatin).
Izvozvo Zvingaita Sei Kudzivisa Kukura Kwekenza?
Statins ine zvigaro zvakawanda mumutumbi. Izvo zvinonzi pro-apoptotic, zvinotsigira nzira yekuputsa masero, kusanganisira tumor cells. Izvo zvinorwisa-angiogenic, zvichiita kudzivirira zvirwere zvekukudziridza ropa. Pasina ropa rinopa, zvipuka hazvigoni kukura uye kupinda mune dzimwe tishu. Zvinokurudzira maitiro emarara kumusana wenyama (NK) masero. Izvi zvingaita kuti muviri wako uwedzere kurwisa muviri wako mukurwisa nekuuraya zviremara kuburikidza nokuzviona semasero ekune imwe nyika asingafaniri kubvumidzwa kuramba achikura mumuviri. Zvose izvi zvinoratidzika sezvipimo zvinogona kuva nemigumisiro yezviremera uye kanhara muhuwandu. Mubvunzo ndeyekuti kune humwe uchapupu hunogutsa hwekuti mitemo inobatsira pakudzivisa kenza kukura nekupararira mumuviri wako.
Tsvakurudzo Inotsigira Ichi Chirevo
Chidzidzo cheIsrael chakawana kuti kushandisa statins kwemakore anopfuura mashanu kunogona kuderedza dambudziko rekudzivirira kenza yekoloni inenge 50%.
Ichi chidzidzo chaisanganisira vanhu vanopfuura 3 000, inenge hafu yeavo vaiva nekenza yekoloni. Izvozvo zvakaratidzika kuva chinhu chinokosha kuwana.
Imwe ongororo yeCanada yakawana kuti kushandiswa kwemasimoni kwakadzikisa zvikuru njodzi yekuve nekenza yekoloni. Asi, vanyori vakaratidza kuti vanenge 4 814 vanhu vaizofanira kurapwa nemitemo kwemakore mashanu ekudzivirira imwe nyaya yekenza yekoloni.
Iyoyo yakawanda kwazvo yemishonga inoitwa mune tarisiro yekudzivirira kungova nhamba shomanana yezviitiko chaiyo zvekenza.
Kutsvakurudza Kwisingabatsiri Chirevo Ichi
Chimwe chidzidzo cheAmerica chakaongorora kusongana kwekodzero ye-cholesterol-kuderedza zvinodhaka uye chiitiko chekenza yekoloni mune vanhu vanopfuura 130 000. Vatsvakurudzi vakawana kuti cholesterol-kuderedza zvinodhaka, kazhinji, hazvina kukanganisa kenza yemukenza yekoloni. Vakataura zvakananga kuti chidzidzo chacho hachina kutsigira pfungwa yokuti mitemo, sekirasi yemishonga, inoderedza zvakanyanya dambudziko rekuve nekenza yekoloni kana rectum.
Zvisinei, sezvo chidzidzo chacho chisina kuongorora mhando dzakasiyana dzemasimoni, haikwanisi kutarisa kuvepo kwekuti mhando dzakasiyana uye zviyero zvemasimita zvinogona kuderedza dambudziko remunhu rekuita kenza yekoloni.
Kubvunzurudzwa kwegore ra2015 kwakagumisa, "hazvisati zvasimbiswa kuti mitemo inokonzera njodzi yekuva nekenza yakawanda, kenza yemazamu, kana kenza yemapapu."
Pasi Pasi
Ko mitemo inoderedza dambudziko remunhu wekuita kenza yemaroni kana kwete? Zvinosuruvarisa, jeri rinenge risiri pamubvunzo iwoyo. Nokuti ikozvino, tichafanira kugadzirisa "zvichida" uye ramba takatarira kune dzimwe tsvakurudzo. Mubvunzo unogona kuratidzwa nenzira imwe neimwe mune ramangwana.
Sources:
Stryjkowska-Góra A, Karczmarek-Borowska B, Góra T, Krawczak K. "Zvinyorwa nekenza." Chimbo Oncol (Pozn) . 2015; 19 (3): 167-75. doi: 10.5114 / wo.2014.44294. Epub 2014 Aug 29.
Hillmer, M. uye Juurlink, D. "Ko Dhiyabhorosi Anoderedza Dambudziko reColorectal Cancer?" Canadian Medical Association Journal 173.7 (Sep. 2005). 1 Sep. 2006.
Jacobs, E. naRodriguez, C. " Statins uye Colorectal Cancer Incidence muUnited States " Journal of the National Cancer Institute 98.1 (Jan. 2006): 69-72. 20 Jan. 2006.
Whitworth, Ariel. " Cholesterol-Kuderedza Zvinodhaka Hazvibatanidzi Nekuderedza Colorectal Cancer Risk. " Journal of the National Cancer Institute 98.1 (Jan. 2006): 1. 20 Jan. 2006.