HPA axis inotsanangurwa ye hypothalamic-pituitary-adrenal axis. Inorondedzera dambudziko rakaoma rekubatanidza pakati pezvikamu zviviri zveuropi-hypothalamus uye planditary gland-uye zvipembenene zvinodarika kana zviduku zvinowanikwa kumusoro kwepfungwa imwe neimwe.
HPA axis chikamu chikuru chegadziriro iyo inodzora mararamiro ako kumanikidziro, kushungurudzika, nekukuvara.
Inobatsirawo kutonga zvimwe zvinhu zvakawanda mumuviri wako, zvakadai sekushisa kwako, kudya, kudzivirira muviri, mafungiro, zvepabonde, nekushandiswa kwesimba.
Zvichipa urongwa urwu hwemabasa, uye nekuenzanisa neanozivikanwa mazita ekusavhiringidza uye zviratidzo zve fibromyalgia uye kusingaperi kuneta kwechirwere , hazvishamisi kuti tsvakurudzo inobatanidza mamiriro aya nekusawirirana muHPA axis.
HPA Axis uye Basa Raro muCentral Sensitivity Syndromes
Ichokwadi, kumwe kutsvakurudza kunoratidza kuti HPA axis inobatsira mukati mehutano hwehutano syndromes , mhuri yezvirwere zve fibromyalgia, kusingaperi kuneta kwechirwere, nemamwe mimwe mamiriro ezvinhu anotendwa arimo. Zvose izvi zvirwere zvakabatana nehuwandu hwekunetseka yepakati yenheyo maitiro (brain and spinal cord.)
Basa reHPA axis mune zvinetso izvi harinzwisiswi zvakakwana, asi kusvika ikozvino, tsvakurudzo inoratidza kuti inoshandisa basa rinokosha. Zvidzidzo zvinoratidza:
- Kupera kweHPA-axis basa kunotungamirira kuderedza cortisol kupindura kudzvinyirira muhutano hwekuneta kwehutano
- Kortisol reactivity yakadzika yakasungirirwa kune zvakanyanya zvirwere zvinotyisa zvirwere zviratidzo ( Kempke)
- Vana vaduku vanoshungurudza vanogona kutungamirira kuHPA-axis dysfunction, iyo inogona kubatsira pakuvandudza kwemamiriro aya
- Nguva dzose unyoro unyanzvi, hwakadai sokutambanudza , unogona kuvandudza HPA-axis basa mu fibromyalgia
- HPA-axis dysfunction inogona kukanganisa kushanda kwefascia (muviri wepasi rese wehutano hunobatanidza) mu fibromyalgia
Vamwe vatsvakurudzi vakakumbira mazano matsva ekurapa anotarisa maitiro asingabatsiri eHPA mumamiriro aya.
HPA axis inobatanidzwawo mukufunganya kwepfungwa , bipolar disorder, post-traumatic stress disorder, kuchipatara kudengenyeka, kuora mwoyo, uye kushungurudza bowel syndrome .
Kunobva:
Borsini A, et al. Psychological medicine. 2014 Jul; 44 (9): 1809-23. Kubatana kwevechidiki mukuvandudzwa kwekuneta kwema syndromes: kuongororwa kwemakore makumi maviri apfuura ekutsvakurudza.
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