Tsvina Relaxer + Anodzvinyirira
Overview
Cyclobenzaprine inonyanyisa musimba inowanika muzvigadzirwa zvechimiro uye pasi pezita rezita rinonzi Flexeril uye Amrix. Inonzi inorambidzwa pamutsara wechipiri ye fibromyalgia.
Ichi chirwere chinogonawo kuva nemigumisiro yakafanana neyeye tricyclic inodzvinyirira, iyo inowanzonyatsorongedzerwa nemamiriro aya.
Cyclobenzaprine haisi FDA-inogamuchirwa kwe fibromyalgia, asi inowanzorongedzerwa kure-label kwairi.
Cyclobenzaprine inodzosera misungo yako nekuita pane yako inonzi nerve system . Vanachiremba vanowanzorondedzera kuti vakuvara kwemasisita pamwe nekurwadziwa kusingaperi.
Mukutsvaga, ichi chinodhaka chakawanikwa chichivandudza hutano hwehutano pamwe chete.
Fibromyalgia Studies
Cyclobenzaprine yakadzidzwa semutambo we fibromyalgia kubva kuma1980, pamwe nemigumisiro yakavhenganiswa.
Kuongorora kwemishonga yemadhora (Smith) yakashandiswa muna 2011 inoshandiswa kwefibromyalgia yakawana kuti chimwe chete chezviedzo zvitatu chakabatanidzwa chakaratidza kuti cyclobenzaprine yakaderedza marwadzo e fibromyalgia. Dambudziko rakabudirira rakaratidzawo kuvandudzwa kwehope, pamwe nekuvandudzwa kwehuwandu. Zvisinei, vatsvakurudzi havana kuwana kusiyana kwakasiyana mumatambudziko, kuneta, kutenderera kwepfundo , kushungurudzika kwemasuru, kana kuti kurwadza kwakakwana.
Kuongororwa kwakawana kuti migumisiro kubva mumiedzo miduku yaive isingakoshi, zvichida nokuti yakaisanganisira vanhu vashomanana.
Ongororo yekare (Tofferi) yemabhuku ezvokurapa inoti fibromyalgia varwere vanotora cyclobenzaprine vaiwanzoita katatu kuti vaudze kurara kwakanaka, zviratidzo zvishoma uye humwe huri nani huri nani kune vanhu vari mumapoka ekudzora.
Zvimwe zvidzidzo zvekare zvakaratidza kuvandudzika munguva pfupi, asi hapana kukosha kwenguva refu.
Muna 2011, chidzidzo chiduku chakaisa pfungwa dzekurara (Moldofsky) yakagumisa kuti chirwere chakanyanya kwazvo cyclobenzaprine chakavandudza kunaka kwekurara kuvanhu vane fibromyalgia. Vatsvakurudzi vakati vakaonawo kuvandudzwa mukurwadziwa, unyoro uye kuora mwoyo .
Dosage
Chimiro chevanhu vakuru che cyclobenzaprine chiri pakati pe5 ne 10 mg, inotorwa kusvika katatu pazuva. Fomu yakasunungurwa-yakasunungurwa, iyo inowanzobatwa mumadhora e15 kusvika ku30 mg kamwe pazuva, inowanikwawo.
Mumutambo we fibromyalgia pahutano hwehutano, vatori vechikamu vakapiwa zvishoma nezvishoma kuwedzera kwema 1 kusvika ku 4 mg, kutorwa chete panguva yokurara.
Dhigirii rezasi inowanzobatanidzwa kune zvishoma migumisiro.
Migumisiro Yechiri
Dzimwe mimwe migumisiro ye cyclobenzaprine yakakomba zvakakwana zvokuti iwe unofanira kuzviudza kuchiremba wako pakarepo. Dzinosanganisira:
- Allergic reaction (rash, mikoko, kuzvimba kwechiso, miromo kana rurimi)
- Kuchepa kwepfupa kana kusuruvara, kunyanya nekurwadziwa kupararira kune fudzi kana ruoko
- Kukurumidza, kukura kana kusawirirana mwoyo
- Kukurumidza kupera simba kana kushaya simba
- Kuvhiringidzwa kana kurasikirwa kwekubatana
- Kamwe kamwe-kamwe misoro
- Hallucinations
- Kugumburwa
- Nausea kana kurutsa
Zviduku zvinokanganisa zvakanyanya zvinosanganisira:
- Dry mouth
- Chiratidzo chakasvibiswa
- Kurara
- Kufirwa kwechido
- Dumbu remarwadzo
- Dhairrhea, kuvimbiswa kana gesi
Shoko Rinobva
Kana iwe uchida kutora cyclobenzaprine, taura nachiremba wako pamusoro pazvo. Anogona kukubatsira kuziva kana mushonga uyu unogona kukubatsira iwe uyewo wakachengeteka kutora pamwe nemamwe mimwe mishonga.
Sources:
Cantini F, et al. Minerva medica. 1994 Mar; 85 (3): 97-100. Abstract chete, nyaya muItaly. Fluoxetin yakabatana ne cyclobenzaprine mukurapa fibromyalgia.
Carette S, et al. Arthritis uye rheumatism. 1994 Jan; 37 (1): 32-40. Kuenzanisa amitriptyline, cyclobenzaprine, uye placebo mukurapa kwe fibromyalgia. Chirwere chekliniki chisinganzwisisiki, ine mapofu maviri.
Moldofsky H, et al. Nyaya ye rheumatology. 2011 Dec; 38 (12): 2653-63. Migumisiro yekurara yakaderera zvikuru chirwere checlobenzaprine pamusoro pezviratidzo uye kurara mupfungwa mune varwere vane fibromyalgia syndrome: inonzi double-blind-randomised placebo-controlled controlled.
Santandrea S, et al. The Journal of International Research Research. 1993 Mar-Apr; 21 (2): 74-80. Chidzidzo chekubata mapofu maviri-mapofu maviri e cyclobenzaprine regimens mu primary primary fibromyalgia syndrome.
Smith B, et al. Kirasi Yezvinodhaka Kuongorora. Oregon Health & Science University; 2011 Kubva Zvinodhaka zveFibromyalgia: Final Final Report.
Tofferi JK, Jackson JL, O'Malley PG. Arthritis uye rheumatism. 2004 Feb 15; 51 (1): 9-13. Kurapa kwe fibromyalgia ne cyclobenzaprine: A meta-analysis.