Anodzvinyirira ndiwo anonyanya kupa mishonga ye fibromyalgia uye isingagumi kuneta , asi iri boka remishonga ine ngozi yakakura yemigumisiro, uye urongwa hwemigumisiro inogona kuitika ndehurefu.
Chirwere chinonzi Viibryd (vilazodone) chinopikira kupa ruyamuro nemigumisiro shoma shoma, uye zvidzidzo zvekurapa zvinoratidza kuti hazvikwanisi kuita kuti uwedzere kuwedzera uye hutano hwepabonde-maitiro maviri anowanzoita kuti vanhu vabve kune dzimwe zvirwere zvinodhaka.
Ndeipi Viibrid Different?
Viibrid chirwere chekudzivirira mwoyo chinonzi SSRI (sarotonin reuptake inhibitor). Asi Viibrid yakasiyana nokuti inowedzera zvinopfuura reuptake.
Reuptake inonyanya kuchengetedza imba kweuropi. Apo imwe neuron (brain cell) inotumira shoko kuno mumwe, inodaro nemakemikari anonzi neurotransmitters , uye serotonin inokosha zvikuru kwatiri, sezvo isu kazhinji hatina zvakakwana kana tisingashandisi zvakanaka.
Paunenge uine serotonin (kana chero yeurotransmitter), shoko rinotumirwa kushandiswa risina simba rakakwana rinobva kune rimwe neuron kune rinotevera. Zvakafanana neti tennis inoshumira iyo isingakwanisi kuwana bhora iri mumambure. Bhoja mukomana anobuda kundotora mabhora aya asina kubvunzwa ari kuita basa reuptake-kubvisa serotonin yakashandiswa kuitira kuti irege kuunganidza zvinhu.
Zvinodhaka zvinononoka kuchinja zvakare kuchengetedza bhora mukomana (chaizvoizvo glial cells uye presynaptic neurons) kubva kubvuta kubvisa neurotransmitter uye kuipa nguva yakawanda yekuendesa shoko rayo.
Kusvika ikozvino, isu takangotarisa kune rumwe rutivi rwetennis tennis. Zvakadini nemurume akayambuka mumambure, neuron ari kugamuchira shoko? Iko sero ine receptors, uye rimwe rega rinogadzirirwa kungogamuchira mharidzo kubva kune dzimwe nyanzvi dzemhepo. Chaizvoizvo, rector yakavharwa, uye chete makemikari akanaka akakwanisa kuizarura.
Viibryd inokonzera dzimwe sarotonin receptors nemakona akafananidzwa uye dzinovanyengedza mukuzarura, zvichiita kuti zvive nyore kuti mharidzo dziyerere kubva pane imwe sero kusvika kune imwe.
Zvatiri kuona ndezvokuti semishonga inowanzova yakanyanyisa nenzira iyi, inoramba ichishanda nemaitiro mashoma. Nokukwira mune imwe nzira uye zvishoma zvishoma iyo huropi hunoita, vanogona kutarisa zviri nani dambudziko iri pane kuchinja basa rekukura kwehuropi izvo zvinodzora zvinhu zvatisingadi kuidya nazvo.
Studies
Kusvika ikozvino, Viibrid haina kumbobvunzwa zvachose nokuda kwe fibromyalgia kana kusingaperi kuneta kwechirwere.
Zvidzidzo, kusanganisira zvimwe zvikuru, zvinoratidza kuti Viibrid inoshanda kuburikidza nehukuru hwekuora mwoyo uye chirwere chinokonzera kushungurudzika, izvo zvese zvinowanzoonekwa kune vanhu vane fibromyalgia uye vasina kupera simba. Zvidzidzo zvakare zvinoratidza kuti zvakanyatsorambidzwa.
Kutsvakurudza kwakabudiswa muna 2017 kwakawana kusakosha kwebasa repabonde kune vanhu vakuru vane utano.
Migumisiro Yechiri
Kunyange zvazvo Viibrid ichiita seine zvishoma zvisingabatsiri pane zvimwe zvinodhaka mukirasi yaro, izvo hazvirevi kuti inotsigira-kushanda pasina. (Hapana mushonga.)
Mumaidzo, zvinowanzova nemigumisiro yakaiswa
- chirwere
- nausea
- chizoro
- kusuruvara
- dambudziko / kurota zvisina kukodzera
- kurutsa
Kana uri kutarisa Viibryd, iva nechokwadi chokuti utaure nachiremba wako uye wemhizimisi pamusoro pezvinogona kuitika.
Chiremba wako uye musimamiti anogona kukubatsira kuti uzive kusanganisa kusina kunaka nemimwe mishonga uye zvinowedzera zvaunotora.
> Sources:
> Clayton AH, Durgam S, Li D, et al. Migumisiro yevilazodone pane zvepabonde muvanhu vakuru vane hutano: zvinokonzerwa nekusarudzwa, kamwe-mapofu, placebo-kutungamirirwa, uye kushandiswa-kushandiswa-kutongwa. International clinical psychopharmacology. 2017 Jan; 32 (1): 27-35.
> Durgam S, Chen C, Gommoll CP, et al. Zvikamu zvekuvandudza muhutano hwehutano kune varwere vane hutano hwakanyanya hwekuora mwoyo huchibatwa nevilazodone: post hoc kuongororwa kwechina maitiro, maitiro e-controlledbo. Neuropsychiatric chirwere uye kurapwa. 2016 Dec 2; 12: 3073-3081. eCollection 2016.
> Shi L, Wang J, Xu S, Lu Y. Kubudirira uye kushivirira kwevilazodone nokuda kwekurwadziwa kukuru kwepfungwa: uchapupu hunobva muchitsauko III / IV chinongororwa nematambudziko. Zvinodhaka zvinodhaka, kukura nekurapa. 2016 Nov 25; 10: 3899-3907. eCollection 2016.