Dambudziko reAlzheimer Rine Utachiona Hwakafanana neCold Common?
Unoshamisika kana iwe unogona "kuwana" chirwere cheAlzheimer kuti usapedza nguva nevanhu vanezvo? Iva nechokwadi chokuti, kubata ruoko rwagogo vako kana kumupa chikwata hachizokupa chirwere cheAlzheimer. Kana kutora basa semukoti anonyatsozivikanwa kumusha unotarisira vakwegura uye kushandisa nguva yega yega kupfeka , kushambidza uye kutarisira vanhu vari munzvimbo dzakachengeteka dzekushaya dambudziko .
Tsvakurudzo pamusoro pekuti Mafuro eAlzheimer anopararira sei
Kunyange zvazvo chirwere cheAlzheimer hachiparidzi kuburikidza nekubatana nevamwe, kumwe kutsvakurudza nemakonzo kunoratidzika kuratidza kuti inogona kuva nemhando yehutachiwana hunotapukira, zvichida yakabatana nemakwenzi (mapuroteni ayo masero europi anoda kushanda). Mune zvirwere zvepecon , kusanganisira Creutzfeldt-Jakob chirwere, prion mapuroteni anotanga kupora zvisina kufanira uye obata zvirwere zvipi zvoutano izvo zvinosangana mukati momuviri, zvichiita kuti masero afire muuropi uye kuora mwoyo kwekukudziridza. Kunyange zvazvo mhembere dzisina kunaka dzakapararira mukati memunhu, hapana chaipo chakaipa chechirwere ichi chinokanganisa vamwe vanhu vakakomberedza munhu uyu, kusanganisira nhengo dzemhuri kana avo vanotarisira munhu iyeye.
Studies naMice
Masayendisiti akaita tsvakurudzo nemakonzo, kutora mishonga ine utano uye kuvayirisa ne beta amyloid protein kubva muhutano hweveveve dzakanga dzakagadzirwa kuti dzive nehutachiona hweAlzheimer uye dzinoratidzira kurasika .
Vatsvakurudzi vakaona kuti mbeve dzakagamuchira jekiseni dzakazopedzisira dzichigadzira mapuroteni anovaka-mavo muhupfungwa dzavo uye kurasikirwa kwepfungwa iyo makonzo ane Alzheimer akatova nawo.
Vatsvakurudzi vakazoedza kutungamirira mapuroteni ane hutachiona nenzira yemuromo, maziso, nemhuno, pamwe chete ne-intravenously, mumakonzo ane utano uye akawana kuti mutsara hauna kutanga zviratidzo zvechirwere cheAlzheimer.
Chimwe chidzidzo chakafanana chakaona kuti mishonga ine utano yakagadzirisa zvakaenzana neAlzheimer apo ubongo hwavo hwakakonzerwa nehupi hutachiona kubva kuvanhu veAlzheimer's.
Kudzokorora Kudzidza nevanhu
Chimwe chekudzorerazve (chidzidzo chinofananidza vanhu vakaiswa pane chimwe chinhu kune avo vakanga vasina) chaive chekutevera vanhu vanopfuura 6 100 vakange vakambovhiringidzwa nehomoni dzekukura kwevanhu. Vatsvakurudzi vakaedza mahomoni aya uye vakaona kuti (vasingazivi panguva iyoyo), vaine zvishoma zviduku uye beta amyloid mapuroteni aripo muhuro hwevanhu vane Alzheimer's. Vanhu ava vave vachiongororwa kuti vaone kana vakagadzira chirwere cheAlzheimer. Kusvika ikozvino, hakuna mumwe wevatori vechikamu akave nechirwere cheAlzheimer, kunyange zvazvo vazhinji vachiri vaduku vachiri vaduku nokuda kwemaitiro ose ekutenda kwemazuva ano.
Inogona Stainless Steel Instruments Kuparadzira Dambudziko reAlzheimer?
Mune imwe yezvidzidzo nemakonzo akarondedzerwa pamusoro apa, vatsvakurudzi vakaputira matare esimbi asina tsvina nemazero maduku emaprotini ane utachiona hweAlzheimer uye akavaisa muhupano hwemakonzo ane utano. Vakaziva kuti mapeji aya akazotevera chirwere cheAlzheimer, asi bedzi kana mhepo dzave dzakabikwa zvisati zvaiswa panzvimbo yekuve plasma inotapira, iyo nzira inobatsira yekuita sterilization.
Vatsvakurudzi vakacherechedza izvi zvichida nokuti zvidzidzo zvekare zvakaratidza kuti chirwere cheCreutzfeldt-Jakob , chirwere chepfungwa chine dzimwe nguva chinonzi "chirwere chemhou chinopenga," chinogona kupararira kubva kune mumwe murwere kusvika kune chinotevera kuburikidza nekushandiswa kwezviridzwa zvisingashandisi zvizere, pamwe chete nedzimwe nzira.
Pane Ngozi Yokubatwa Nezvirwere zveAlzheimer's?
Sayenzi ichiri kushanda pakugadzirisa chinonyanya kukonzera chirwere cheAlzheimer. Tinoziva kuti zviitiko zvinopisa sezera, genetics, nhoroondo yemhuri uye mararamiro evanhu vose zvikamu zvemufananidzo. Zvinogonawo kuti zvinhu zvinotapurirana zvakadai semabhadharo zvinogona kunge zvakabatanidzwa muAlzheimer's disease, asi izvo zvinogona kunge zvisina kuvhiringidzika panguva ino uye zvinongotarirwa chete pakutsvakurudza kwokutanga nemakonzo.
Kana zvikaitika kuti minyengetero inobatsira mune chirwere cheAlzheimer, zvakakosha kuyeuka kuti zvirwere zvepachioni hazviparidzi kuburikidza nekushamwaridzana kana kunyanya kufanana nekubatana nevamwe. Saka, famba mberi uye ukumbundira munhu uyo ane Alzheimer's. Chirwere chavo hachina kupararira chero ipi zvayo, uye vanogona kuwana zvimwe zvingabatanidzwa zvine chokuita nekubata kwepamusoro kwevanhu vane dambudziko rekushaya mvere , kusanganisira kuderedza kushanda kweropa, kuderedza kurwadziwa uye kuderedza zvinetso zvinopesana mukuora mwoyo .
Shoko kubva
Hazvisi zvisizvo kuva nehanya nekutarisana nechirwere, kunyanya kana iwe usingazivikanwi nemamiriro acho kana kuti nei mumwe munhu arikukura. Kunyange zvazvo pane zvinhu zvakawanda zvatisinganzwisisi nezvehutano hweAlzheimer, tinoziva nechokwadi kuti kupedza nguva nevanhu vane Alzheimer's, kuvakumbatira kana kuvatarisira hakuzoiti kuti iwe uve neAlzheimer's.
Sources:
JAMA Neurology. 2013 Apr; 70 (4): 462-8. Kuongororwa kwekukanganisa kusagadzikana kweAlzheimer uye Parkinson chirwere chepuroteni muigamuchiri ye-cadaver-yakagadzirwa nekukura kwehomoni. http://www.ncbi.nlm.nih.gov/pubmed/23380910
Nhamba yeNeuroscience.15 May 2000, 20 (10): 3606-3611. Uchapupu hweSeeding ye β-Amyloid neIntracerebral Infusion yeAlzheimer Brain Extracts mu β-Amyloid Precursor Protein-Transgenic Mice. > http://www.jneurosci.org/content/20/10/3606
Molecular Psychiatry 17 , 1347-1353 (December 2012) | doi: 10.1038 / mp.2011.120. De novo induction of amyloid-β demo mu vivo. https://cen.acs.org/articles/90/i27/Alzheimer-Prion-Connection.html
Proceedings ye National Academy of Sciences yeUnited States of America. August 4, 2009.106 (31). Kunyunyuta kwehutano β-amyloidosis: Intracerebral versus systemic Aβ inoculation. http://www.pnas.org/content/106/31/12926.full