Tsanangudzo yeEngraftment uye Chii Chiri Kuitika MuStem Cell Your Transplant
Engraftment mu stem cell transplantation apo muviri wako unogamuchira kuiswa kwemafupa emasero kana masero ematsipa, uye anotanga kubudisa masero matsva eropa uye maune immune system masero. Ndiyo danho riri mukubudirira stem cell transplant.
Chii Chinoitika Mumagetsi eStem kana Bone Marrow Kubika?
Ropa rekenza rinogona kurapwa nekuuraya mafupa ako emasero uye masero emashizha ane radiation kana chemotherapy kuparadza masero ekenza.
Vanhu vane dzimwe mhando dzekenza vangadawo tsvina yesero kupemha nekuda kwemigumisiro yemirasiyo kana chemotherapy. Iyi mishonga inogona kuva nemigumisiro yechiratidzo chekuvadza marora emasora uye masero ematsipa, uye kana kukanganisa kwacho kwakanyanya, kuiswa kunodiwa kunodzosera basa remafupa emapfupa. Vamwe vanhu vangave vachida kutsvaira marora pamusana pekutsvaga kwemairasi kana makemikari kana mamwe mamiriro ezvinhu anokanganisa mafupa avo.
Munguva ye stem cell transplantation, bone marora omugamuchiri anorasika nemakemikirini ane kana kuti pasina remirasi yemajoini kusvika pakusakwanisa kushanda. Inoshandiswa kusakwanisa kubereka masero matsvuku eropa, maplatelet kana masero machena eropa. Kutaura zvazviri, kukanganisa kwakanyanya kwazvo zvokuti murwere achafa kunze kwekuti marora avo aita basa rinodzorerwa nekunzwa kwemasero emasero, zvichibva kumunhu anopa, kana masero emurwere ayo akambotorwa uye akachengetwa.
Kana kamwechete masero ekudzikinurwa akaiswa mukati momupiki, anowana nzira yavo mumumvuri nzvimbo mumapfupa. Apo ivo vari munzvimbo uye vanotanga kubereka, engraftment inowanikwa. Masero ekudzivirira achaumba itsva hematopoietic uye immune system yeaigamuchira.
Chii Chiri Kuitika Pakati Pemagetsi?
Masero emarara kana marora anopiwa sekuwedzerwa ropa.
Mumazuva mashomanana apfuura mushure mekugadziriswa kwemavara, maitiro emagetsi anosimudzirwa anomhanyira kumapfupa eropa uye anotanga nzira yekugadzirisa masero eropa. Zvinotora mazuva anenge 12 kusvika ku15 mushure mekunyudzwa kwemasero emadziro kutanga kutanga masero matsva eropa. Mishonga inonzi chikwata-chinokurudzira chinogona kupiwa panguva ino yekuwedzera kushandiswa kwesero rekuisira ropa. Masero matsva anosanganisira masero matsvuku eropa, masero machena uye maplatelet. Kana kambani yekugadzira ikatanga, engraftment inonzi yakamboitika.
Nhamba yako yakakwana yeropa ichaongororwa nguva nenguva kuti uone kana ingraftment iri kuitika. Kuwedzera kwenguva pfupi uye kwakasimba mumasero eropa kunoratidza kuti kunyora kunoitika. Pakutanga pane izvi, sendimbe yakakwana yeropa icharatidza kukwira mumasero machena eropa uye kuchinja kubva kune dzakawanda lymphocytes kusvika kune neutrophils.
- Nhamba ye absolute neutrophil (ANC) ye500 kana kupfuura kwemazuva matatu mumutsara chiratidzo che engraftment. Pamusana pemafuta kana purogiramu yemasero emuviri (PBSC), vaparidzi, neutrophil engraftment inogona kuitika mushure memazuva gumi mushure mekugadziriswa asi inowanzove yakapoteredza mazuva 14-20.
- Nhamba yeplatelet ye 20,000 kusvika ku50,000 chiratidzo cheplatelet engraftment. Kune marora kana PBSC vagamuchirwa, platelet engraftment inowanzoitika nguva pfupi mushure mekunge neutrophil engraftment.
Kusvikira nguva yakazara yakazara, kune ngozi yakanyanya yehutachiona, kuperevedza ropa, uye kubuda ropa kwakakonzerwa - zvose izvo zvinokonzerwa nechepasi masero eropa. Kuti vabatsire kubvisa chiitiko ichi, kuendeswa kwevakagamuchira vanogona kupiwa sero tsvuku dzeropa uye kuwedzerwa kweplatelet munguva yekudzorera. Migumisiro ye-high-dose chemotherapy uye kurasikirwa kwemasero eropa kunowedzera simba rekudzivirirwa kwemuviri, saka kwemavhiki maviri kusvika maviri mushure mekugadzirwa, varwere vanonyanya kunetseka kuwedzera zvirwere. Nokudaro, ma antibiotic anowanzotarisirwa kuti abatsire kudzivirira utachiona.
Inogona kutora mwedzi yakawanda kusvika kune imwe chete kusvika kumakore maviri kuitira kugadzirisa zvakakwana kwekudzivirira kwezvirwere mushure me engraftment.
Inowanzoitika nokukurumidza kwekugadzirwa kwevologogous kune kugovera zvipo. Iwe uchange uine kuongororwa ropa kuti uone kuti masero ari kubudiswa ari masero matsva panzvimbo pemasero ekenza anodzoka. Iwe unogonawo kuva nefupa remafupa ekutema kuti uone kuti marora matsva ari kushanda sei.
Mhedziso yekupedzisira ndiyo inoshanda zvakakwana mapfupa emasero anokonzera masero emasero matsvuku emasero matsvuku eropa, masero emachena eropa uye maplatelet, kusanganisira dzose dzakasiyana-siyana dzemasero machena - lymphocytes, granulocytes uye monocytes.
Shoko Rinobva
Nguva dzekudzorera dzinopesana kubva kumunhu kumunhu. Vasati vauya sekushandiswa kwekufambisa mutero vanogona kubva muchipatara, vanogona kukwanisa kudya nokunwa mvura zvakakwana, vasina fivha, vasina tsvina kana chirwere, uye vane maitiro akachengeteka evanhu vose masero eropa. Vanhu vanofambisa vanogona kunge vachiri kuneta nyore uye vanonzwa vasina simba kwemwedzi, zvisinei, muchikamu nokuti zvinotora nguva kuti maitiro ezvirwere zvekudzivirira zvirwere apone.
Vamwe vanhu vangave vachida kugara muchipatara kwenguva refu kana matambudziko achikura. Kukundikana kwekutsinhanisa ndechimwe chinhu chisingawanzo asi chakakomba chepfupa remapfupa anoputika, uye inogona kukura apo masero matsva asingawedzere kana kuti muviri wemuviri wemuviri anoramba masero. Muzviitiko zvisingawanzoitiki, boka rako rezvehutano rinokutaurira pamusoro pezvaunogona kuita.
> Sources
> Kekre N, Antin JH. Hematopoietic stem cell cell transplantation vanopa zviwanikwa muzana remakore rechi21: kusarudza mupi wezvakanaka kana mutambo wakakwana usipo. Ropa . 2014; 124 (3): 334-43.
> Chang L, Dzingira D, Braun T, et al. Engraftment syndrome inotevera allogeneic hematopoietic cell transplantation inofananidzira varombo
migumisiro. Biol Ropa Marrow Kubika . 2014; 20 (9): 1407-1417.
> National Cancer Institute. Ropa-kuita stem cell cell transplants. Yakasvika muna August 2017.