Bone marrow disorder
Mu aplastic anemia (AA), marora emapfupa anomira kugadzira masero matsvuku eropa, masero eropa, uye maplatelet. Aplastic anemia inogona kuonekwa chero ipi zvayo asi inowanikwa kakawanda muvana nevakuru vechidiki. Dambudziko racho rinowanikwa munenge pakati pevanhu vaviri kana vatanhatu kusvika mamiriyoni evanhu munyika yose.
Vanenge makumi maviri kubva muzana yevanhu vanokura aplastic anemia sechikamu chehutano hwakaberekwa hwakafanana neFanconi anemia , dyskeratosis congenita, kana Blackfan Diamond anemia .
Vanhu vazhinji (80%) vakawana aplastic anemia, zvinoreva kuti yakakonzerwa nehutachiona hwakadai sehepatitis kana Epstein-Barr, utachiona hunoisa kune mazai uye makemikari, kana zvinodhaka zvakadai se chloramphenicol kana phenylbutazone. Kutsvakurudza kunoratidza kuti rethistemia anemia inogona kunge iri mugumisiro wehutachiona hwemoto.
Zviratidzo
Zviratidzo zveaplastic anemia zvinouya zvishoma nezvishoma. Zviratidzo izvi zvine chokuita nehutano hwemasero eropa:
- Nhamba shoma dzemasero matsvuku eropa zvinokonzera chirwere chemhuka, zvine zviratidzo zvakadai semusoro, chizungu, kuneta, uye kupera (pallor)
- Nhamba shoma yeplatelets (inodiwa kuti ropa rive nehutachiona) inokonzera kubuda ropa kunoshamisa kubva mumasamu, mumhino, kana kuputika pasi peganda (maduku maduku anonzi petechiae)
- Nhamba shoma yemasero matsvuku eropa (zvakakosha pakurwisana nehutachiona) inokonzera zvirwere zvinowanzoitika kana chirwere chinopera.
Kuziva
Zviratidzo zveaplastic anemia zvinowanzotarisa nzira yekuwana chirwere. Chiremba achawana ropa rakazara reyero (CBC) uye ropa richaongororwa pasi pe microscope (ropa smear).
ICBC icharatidza hutsika hwemasero matsvuku, masero machena, uye maplatelet muropa. Kutarisa kumasero pasi pe microscope kuchasiyanisa kushandiswa kwemapiritsi anemia kubva kune dzimwe dambudziko reropa.
Mukuwedzera kune kuongororwa kweropa, bone marrow biopsy (sampuli) inotorwa uye iongororwa pasi pe microscope.
Mu aplastic anemia, icharatidza mashoma masero matsva eropa achiumbwa. Kuongorora marora emapfupa kunobatsirawo kusiyanisa kuputika kwepachikafu kubva kune mamwe maronda emasopa, sezvakaita myelodysplastic disorder kana leukemia.
Staging
Kurongedza kana kuisa chirwere ichi chirongwa chinobva kune International Aplastic Anemia Study Group, iyo inotsanangura maitiro maererano nenhamba dzemasero eropa aripo muropa rekuongorora uye marora marrow biopsy. Aplastic anemia inorondedzerwa seyakaderera (MAA), yakaoma (SAA), kana yakaoma kwazvo (VSAA).
Kurapa
Kune vanhu vaduku vane anemia inoputika, fupa remafu kana kuti stem cell transplant inotsiva chinokanganisa bone marrow nemasero anopa ropa anogadzira. Kudyara kunotakura njodzi dzakawanda, saka dzimwe nguva hazvishandisi sechirapi kune vanhu vakura kana kuti vakwegura. Vanenge makumi mapfumbamwe nezana (80%) vevanhu vanogamuchira mapfupa ekutemwa kwemafuta vane kupora kwakakwana.
Kune vanhu vakwegura, kurapwa kweaplastic anemia inotarisa kudzvinyirira masimba ezvirwere neAtgam (anti-thymocyte globulin), Sandimmune (cyclosporine), kana Solu-Medrol (methylprednisolone), oga kana kuti pamwe chete. Mhinduro kumushonga wemishonga inononoka, uye anenge chikamu chetatu chevanhu vanodzokerazve, izvo zvinogona kupindura kumativi maviri emishonga.
Vanhu vane aplastic anemia vachabatwa neruzivo rweropa (hematologist).
Kubva kune vanhu vane apemia anemicia vane nhamba shoma yemasero eropa, ivo vari pangozi yekutapukirwa. Nokudaro, kudzivirira zvirwere, uye kuvabata nokukurumidza kamwe chete pavanoitika, zvinokosha.
Kunobva:
"Aplastic Anemia." Nezvirwere. 10 Nov 2006. Aplastic Anemia & MDS International Foundation, Inc .. 2 Dec 2006