Hemolytic anemia inorondedzera boka guru rezviitiko zvinoratidzirwa nekuparadzwa kwemasero matsvuku eropa. Ivhareji yeupenyu huri tsvuku dzeropa remazuva 120. Pakupera kwemazuva makumi maviri, sero rega rega rega rakaputsika uye zvikamu zvaro zvinoshandiswa zvakare kuti zviite zvitsva. Apo masero ako matsvuku eropa akaputsika pasi nekukurumidza kudarika izvi, anonzi hemolysis.
Hemolysis inogona kukonzerwa nezvinhu zvakawanda zvakasiyana. Mamwe mafomu iwe unotora nhaka, sefa nhaka spherocytosis uye pyruvate kinase inoshaya . Zvimwe zvinokonzerwa nehutachiona hwako huputsa masero matsvuku eropa, semoto autoimmune hemolytic anemia kana hemolytic zvirwere zvechechecheche . Muzvinodhaka-induced hemolytic anemia, kune nzira dzakasiyana-siyana dzinokonzera hemolysis kana iwe uchitarirwa kune mishonga kana chepfu.
Zviratidzo nezviratidzo
Zviratidzo nezviratidzo zvezvinodhaka-induced hemolytic anemia zvakafanana nedzimwe mhando dze hemolytic anemia. Zviratidzo izvi zvinosiyana zvishoma nezvishoma kana serofu yeropa yakavhuniwa apo iri kupararira (intravascular hemolysis) kana kunze kwevascular system (kunyanya chiropa uye spleen). Zviratidzo zvako zvinogona kusanganisira:
- Jaundice, kuchena kweganda
- Rima (tea kana cola mavara) urini
- Pallor, iyo yakajeka ruvara rweganda
- Kuneta, kuneta
- Chizutu
- Yakawanda mwoyo yezinga
- Kupfupika kwemhepo
- Splenomegaly, yakawedzera spleen
Kuziva
Kuongororwa kwezvinodhaka-induced hemolytic anemia kunotanga semhando dzakawanda dzeanemia, nehuwandu hwekuverenga ropa (CBC). Kuora muviri kunoratidzwa nehaemoglobin yakaderera uye / kana hematocrit. Mu hemolytic anemia, iro tsvuku rekuisira ropa rinokurumidza kuwedzera pakuwedzera kwenhamba ye reticulocytes, masero matsvuku eropa.
Uyu muedzo unowanzonzi chirevo uye unogona kuonekwa seperesenti kana kuti absolute reticulocyte count (ARC).
Kuti uongorore hemolytic anemias, zvinokosha kune mumwe munhu (zvichida iwe hematologist kana chiremba) kuti utarise masero ako matsvuku pasi pe microscope. Uyu muedzo unonzi peripheral blood smear. Ropa tsvuku rinowanzotarisa kumativi ose, rakaenzana ne donut pasi pe microscope, asi apo sero rebhupa tsvuku rinoparadzwa nguva isati yasvika iyo inoparadzaniswa kana yakaumbwa semasero kana globes.
Mamwe mishonga inokonzera immune hemolytic anemia yakafanana ne autoimmune hemolytic anemia. Kana iwe uine izvi, muedzo unonzi "direct antitiglobulin test" (DAT kana Direct Coombs) ichava yakanaka inoratidza kuti maitiro enyu ezvirwere zvekuzvidzivirira ari kurwisa uye kuparadza masero enyu matsvuku eropa zvisina kunaka. Nemhaka yekuti serofu tsvuku yeropa inosunungura bilirubin, imwe yenguruve inokonzera jaundice, mazinga ako ebilirubin angasimudzwa. Kana zvisina kudaro, hapana mimwe miedzo chaiyo kuti uone kana mushonga wako chiri chikonzero che hemolytic anemicia. Muzhinji, kuongororwa kunosimbiswa kana chirwere chenyu chemainemiri chinowedzera mushure mokurega mishonga.
Zvinokonzera
Kune mishonga yakawanda inosanganiswa nemishonga-induced hemolytic anemia.
Zvivi zvakakurumbira ndezvi:
- Cephalosporins, mishonga inorwisa mabhakitiriya, kusanganisira ceftriaxone
- Penicillins, kunyanya piperacillin
- Diclofenac, kwete-steroidal anti-inflammatory
- Oxaliplatin, chemotherapeutic mishonga
Chimwe chiitiko chakafanana chinonzi glucose-6-phosphate dehydrogenase (G6PD) inoshaya. Mune rudzi urwu rwehutachiwana hwehutachiwana, hauna kukwanisa kushandisa enzyme (chemikemikisi) muropa rekundu reropa. Kana iwe uine humwe mishonga yakadai sulfa antibiotics, masero ako matsvuku eropa angaita hemolyze achikonzera chirwere chemaemia. Kana uine kushayikwa kweG6PD, zvakakosha kuti iwe uzive kuti mishonga / zvikafu zvaunofanira kudzivisa .
Treatment Options
Mishonga yekurapa inotsanangurwa nekushushikana kwekushaya ropa kwako.
Kutanga, mishonga / tsvina inokonzera hemolytic anemia inofanira kumira. Kuwedzerwa ropa kunogona kupiwa kana zvichidikanwa. Kana hemolysis yakanyanya, inogona kukonzera kuora kwepvo. Nenzira inofadza, izvi zvinowanzoitika kwenguva pfupi uye zvinovandudza kana hemolysis inogadzirisa, asi izvi zvingada dialysis kwechinguva.
Shoko Rinobva
Zvingaita sezvisinganzwisisiki kuziva kuti mishonga yauri kutora kune imwe mamiriro ehutano yakakonzera kushaya ropa. Nenzira yakanaka, kubvisa mishonga inokanganisa ichaita kuti hemolysis irege kuwedzera. Zvakakosha kukurukura nachiremba wako kuti mishonga yakakonzerai anemia kuitira kuti iwe usakwanisa kuishandisa munguva yemberi.
> Sources:
> Schrier SL naBrugnara C. Pathogenesis ye autoimmune hemolytic anemia: Huru agglutinins nemishonga. Mu: UpToDate, Post, TW (Ed), UpToDate, Waltham, MA.
> Schrier SL. Hemolytic anemia nemhaka yemishonga uye chepfu. Mu: UpToDate, Post, TW (Ed), UpToDate, Waltham, MA.