7 Zvinhu Zvaunofanira Kuzvidzivirira Kana Une G6PD Kukwana

Glucose 6 Phosphate Dehydrogenase (G6PD) kushayikwa inokonzerwa nerudzi rwehemolytic anemia , chirwere chekushaya ropa chinowanikwa apo masero matsvuku eropa anowedzerwa nekukurumidza kudarika nguva dzose (inonzi hemolysis ). Muchikamu cheG6PD izvi zvinowanzoitika nokuti iwe unogadzira huwandu hwakaderera hweG6PD, iyo enzyme inodzivirira sero tsvuku yeropa kubva mukukuvara. Nenzira yakanaka, vanhu vazhinji vane G6PD kushayikwa havana matambudziko zuva nezuva. Zvisinei, kune mamwe mishonga kana zvikafu zvinowedzera mukana wekutsvaira masero eropa. Ngationgororei zvimwe zvezvinhu zvinowanzokonzera zvinetso mune chirwere ichi cheropa.

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Antibiotics

Vanhu vane chirwere cheG6PD vanogona kushivirira mishonga yakawanda yemishonga inorwisa mabhakitiriya asi vanofanira kunge vachiziva vashoma vasarudzo vanogona kutanga chirwere chemasero matsvuku eropa chinotungamirira kuanemia. Mishonga inorwisa mabhakitiriya inonzi "sulfa" zvinodhaka zvinofanira kudziviswa. Izvi zvinorwisa mabhakitiriya zvinowanzoshandiswa kurapa ganda kana urinary tract (bladder) zvirwere. Chimiro chakajairika chemishonga inorwisa mabhakitiriya inowanikwa nemazita ezita Septra kana Bactrim (sulfamethoxazole-trimethoprim).

I "quinolone" antibiotics inofanirawo kudziviswa. Mishonga mbiri yakajairika yakawanda iri muboka iri ndi Cipro (ciprofloxacin) uye Levaquin (levofloxacin). Izvozvo zvinorwisa mabhakitiriya zvinowanzoshandiswa kuvanhu vakuru kuti vabate zvirwere zvekuvhota uye pneumonia. Mimwe maantibayoti inofanira kudziviswa anosanganisira nitrofurantoin uye dapsone.

Nenzira, kune mishonga yakawanda inorwisa mabhakitiriya iyo vanhu vane G6PD inoshaya vanogona kutora zvakachengeteka. Iva nechokwadi chekukurukura izvi nechiremba wako kana une G6PD inoshaya uye unoda kurapwa kwemishonga inorwisa mabhakitiriya.

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Malaria Mishonga

Primaquine, mushonga unoshandiswa kurapa kana kudzivirira marariya , inogona kukonzera matambudziko ehemolytic kuvanhu vane G6PD inoshaya. Nokuda kweizvi zvinogona kuitika, zvinokurudzirwa kuti vanhu vaongorore kushayikwa kweG6PD vasati vatora primaquine. Izvi zvinosanganisira kuyamwisa vana vane amai vanotora primaquine. Nenhamo, mamwe mishonga inoshandiswa kurapa marariya inobvumirwa nevanhu vazhinji vane G6PD inoshaya.

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Mishonga Inoshandiswa muCcercer Treatment

Rasburicase imishonga inoshandiswa kurapa tumor lysis syndrome, chirwere chezvechipatara chehematologic kanzira yakadai seyeukemia, haifaniri kushandiswa kune vanhu vane G6PD inoshaya. Nokuda kweizvi ngozi, zvinokurudzirwa kuti vanhu vaongorwe vasati vawana rasburicase. Saizvozvowo, doxorubicin, rudzi rwekemotherapi rinoshandiswa kurapa mhando dzakawanda dzekenza, rinogona kukonzera kupera kwemasero eropa muvanhu vane mamwe marudzi eG6PD kukwana.

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Aspirin

Aspirin, inowanzoshandiswa kurapa marwadzo kana kuputika, inofanira kudziviswa. Vamwe vanhu vanotora aspirin zuva rega rega sechikamu chehurongwa hwehutano hwavo. Kana uchidzivirira aspirin, zvinokosha kuyeuka kuti inowanikwa kune vakawanda pamusoro pemishonga inoshandiswa seAnacin, Bufferin, Ecotrin, Excedrin, BC Powders uye Goody's Powders. Inowanikwawo muPepto-Bismol. Mune dzimwewo dzakawanda pamusoro pemarwadzo ekurwadziwa anoremekedza sezvakaita acetaminophen kana ibuprofen zvinoregererwa pasina nyaya.

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Mothballs

Hongu, vanhu vachiri kushandisa mothballs. Mothballs inogona kuva nekemikari inozivikanwa se naphthalene iyo inogona kukonzera hemolysis kuvanhu vane G6PD inoshaya. Nafthalene inogonawo kuwanikwa mumitsvina, kunyanya iyo inoshandiswa kuchengetedza njoka. Nafthalene ndiyo mhepo yakapiwa nemishonga iyi kuitira kuti kutsvaga kuve kunobva pakuvhiringidza mhepo kana kuidya.

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Henna

Pano pane nyaya dzakabudiswa dzakabudiswa zvichiratidza henna (yakashandiswa kwekanguva dzemavara kana kuti bvudzi dhayi) yakakonzera matambudziko ehemolytic kuvanhu vane G6PD inoshaya. Vacheche vasati vava nemakore maviri vanoita sevanowanzoita izvi.

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Fava Nhamba

G6PD kushayikwa kunonziwo favism; kunyanya miitiro yakaoma zvikuru yeG6PD inoshaya. Izvi ndezvokuti kuiswa kwefea (iyo inozivikanwawo sevhisi yakawanda) inogona kukonzera hemolytic kurwisa kune varwere vane G6PD inoshaya. Vamwe vanoti mbeu dzose (dzakadai semaperesi, lentile, kana mhete) dzinodziviswa, asi kana kana izvi zvisingadikanwi hazvizivikanwe.

Shoko Rinobva

Kana uine kushayikwa kweG6PD, hazvirevi kuti haugone kutora mishonga. Iwe unofanirwa kunge uchiziva nezvemishonga inowanikwa kuti urege. Iyi haisi nhoroondo yakakwana yezvinhu izvo vanhu vane G6PD kushaikwa vanofanira kudzivisa. Kune mimwe mishonga inongoita kuti red cell breakdown kana inotorwa mumadhora akawanda. Vamwe chete vanokonzera matambudziko mumhando dzakasiyana dzekushayikwa kweG6PD. Iva nechokwadi chekukurukura mishonga yako yese mitsva nechiremba wako kuti ave nechokwadi chokuti haisi kupikiswa kune vanhu vane G6PD kukosha.

> Kwakabva:
> Luzaatto L uye Poggi V. Glucose-6-Phosphate Dehydrogenase Kukwana. Mu: Orkin SH, Fisher DE, Ginsburg D, Tarisai AT, Lux SE uye Nathan DG (Eds). Hematology uye Oncology yeMucheche uye Kuberekwa (8th ed). Philadelphia: Elsevier.