Beta blockers vane zvakawanda vanoshandiswa mukurapa. Imwe yezvinonyanya kukosha ndeyekuporesa varwere vane coronary artery disease (CAD) uye angina.
Beta Vanovharidza Sei Kubatsira Varwere Vane Angina?
Mune varwere vane angina yakagadzikana inokonzerwa neCAD, beta blockers inofungidzirwa shanduro yekutanga-line.
Mune zvakagadzirwa angina, rimwe kana kuti mamwe emakironi anonzi coronary anenge akavharirwa neatrosclerotic plaque .
Kazhinji, mutsara wemwoyo unopiwa nechirwere chinorwara unowana ropa rakakwana panguva dzezororo. Asi panguva yekurovedza muviri kana nguva yekudzvinyirira, kuvharwa kwechikamu kunodzivirira kubuda kweropa kubva pakuwedzera zvakaringana kugovera oxygen inodiwa kumushonga wemwoyo wakashanda, uye musuru unova ischemic (unoshayiwa oksijeni). Somugumisiro, angina inoitika.
Beta blockers vanoshanda nekudzivisa kuitika kweAdrenaline pamwoyo. Izvi zvine mazano maviri anobatsira muvarwere vane angina:
- Kupera kwemaitiro emwoyo, kunyanya munguva dzekurovedza muviri kana kushungurudzika.
- Kuderedza simba remoyo mususu kuputika.
Zvose izvi zvinogadzirisa kuwanda kwe okisijeni inodiwa nemutsipa wemwoyo, uye ischemia (uye angina) inonoka kana kudziviswa semugumisiro.
Chii Chinokonzerwa NeBeta Blockers Muvarwere Na Angina?
Mune varwere vane angina, beta blockers inowanzobudirira mukuvandudza kushanda kana nguva yezviito zvinogona kuitwa kunze kwekuita ischemia kana angina.
Varwere vane angina vakachengeteka vanotora beta blockers kazhinji vanoona kuoneka kwechikamu chezvikamu zve angina uye vanofanira kutora nitroglycerin zvishoma.
Mukuwedzera, mune varwere vane angina avo vane chirwere chemyocardial infarction . (kurwisa kwemwoyo), beta blockers ndivo chete vanorwisa-angina zvinodhaka izvo zvakaratidzwa kuderedza dambudziko rekuve neimwe myocardial infarction.
Uyezve, kune avo vanopona marocardial infarction, kana kune varwere vane mwoyo yekukundikana mukuwedzera kune angina dzakasimba, beta blockers zvakaratidzwa kuti inonyatsovandudza kupona kwehupenyu hwose.
Zvikomborero zvakapiwa neBeta blockers zvakavaita mishonga yekusarudza kokutanga pakurapa varwere vane CAD uye vakagadzikana angina.
Migumisiro Yechipfuva yeBeta Blockers
Izvozvo zvikamu zvinokonzerwa neBeta blockers zvinosanganisira bradycardia (inononoka mwoyo yehutano), zvinetso zvekufema kune vanhu vane chirwere chepamu kana chirwere chisingaperi chemapapu, kuneta, kuwedzera kwezviratidzo zvehutachiona hwehutano , kuora mwoyo, uye kushaya simba kwe erectile . Beta blockers inofanirawo kudzivirirwa nevarwere vane angina nekuda kweMichirzmetal's angina (coronary artery spasm) , sezvo muvatachiona beta blockers pane dzimwe nguva zvinokonzera kupararira kwakawanda.
Zvakawanda zvemigumisiro iyi zvinogona kudzivirirwa nevarwere vane angina nekushandisa beta blockers iyo inoshanda zvikuru pamwoyo pachake, uye iyo ine zvishoma zvishoma pamidziyo yeropa, mapapu, uye pakati pehutano hwemagetsi. Iyi "cardioselective" beta blockers ndeye Tenormin (atenolol) uye metoprolol (Lopressor, Toprol XL).
> Kwakabva:
> Fihn SD, Gardin JM, Abrams J, et al. 2012 ACCF / AHA / ACP / AATS / PCNA / SCAI / STS Nhungamiro yeKutsvaga uye Kutarirwa Kwevarwere Nekasimba Ischemic Heart Disease: Nhoroondo yeAmerican College of Cardiology Foundation / American Heart Association Task Force pamusoro Pemitemo Yezvokuita, uye American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, uye Society of Thoracic Surgeons. Circulation 2012; 126: e354.