Ndeapi Maantibayoti Anoshanda Ipi Mhando dzeAgne?
Nei maantibayoti anoshandiswa kumashonga? Ko mushonga unorwisa mabhakitiriya unoshanda kune marudzi akasiyana-siyana ezviratidzo zvechirwere here? Vanhu vane acne uye dermatologists vanosarudza sei chirongwa chakarurama?
Overview
Mishonga inorwisa mabhakitiriya inowanzoshandiswa kurapa masheya sezvo ichibatsira kuderedza nhamba yebhakitiriya mukati uye kumativi ose chikwata chepurosebaceous , chine bvudzi rebvudzi, gara rebaceous, uye bvudzi.
Acne inokonzerwa nemigumisiro yehomoni pane iyi unit.
Kunyanya, iyo follicle inodzivirirwa uye kuwanda kwechirwere chepachigara chinowanzoitika, Propionibacterium acnes , kunokonzera kuparadzwa kweganda re follicle. Izvi zvinobvumira follicular nyaya kupinda muhara, zvichiita kupindura kwekupisa.
Maitiro Avanoita
Maantibayoti anoshanda nenzira dzinoverengeka. Nzira inonyanya kukosha ndeyekuderera kwehuwandu hwebhakitiriya mukati uye nepamusoro pe follicle. Mishonga inorwisa mabhakitiriya inoshandawo nekuderedza makemikari anotsamwisa anokonzerwa nemasero machena eropa. Pakupedzisira, mishonga inorwisa mabhakitiriya inoderedza kusanganiswa kwemafuta emafuta asiri mu sebum, uyewo kuderedza kupisa kwekupisa.
Aina
Mishonga inoshandiswa kakawanda inoshandiswa mishonga inopfupikiswa apa.
Tetracycline
Tetracycline ndiyo inonyanya kunyoreswa mishonga inorwisa mazino. Iyo inowanzotanga mazamu inonzi 500 mg kaviri pazuva inoramba ichienderera mberi kusvika kuderera kukuru kwezvipembenene zvechigunha zvichionekwa.
Mukana wacho unogona kuderedzwa kusvika 250 mg kaviri pazuva kana kubviswa. Iko kutsvaga kukuru kwechirwere ichi ndeyekuti inofanira kutorwa pachirwere chisina chinhu kuti ive yakakosha zvikuru. Kune mukomana wechidiki anodya kazhinji, izvi zvinogona kuva zvakaoma zvikuru. Tetracycline haifaniri kupiwa kuvakadzi vane pamuviri kana vana vari pasi pemakore mapfumbamwe emakore.
Erythromycin
Erythromycin iyi inowanzoshandiswa mishonga inorwisa mabhakitiriya. Iine zvikomborero zvakasiyana pane tetracycline. Chokutanga, ine anti-inflammatory properties iyo inobatsira kuderedza kubwinya mumashure pamwe nekuuraya mabhakitiriya. Uyezve, inogona uye inofanira kutorwa nechingwa-kubatsira kwevechiri kuyaruka. Muyero we erythromycin husiyana nemhando inoshandiswa, asi inowanzomirirwa se 250 - 500 mg kaviri pazuva. Izvozvo zvinogona kukonzera kushushikana uye kushungurudza asi kunogona kushandiswa muvakadzi vane pamuviri. Erythromycin inotengeswa pasi pemazita: Ilotycin, Ery-Ped, Ery-tab, Staticin, Erythra-Derm, Akne-mycin, Pce, Eryc, Ery, Eryped, T-Stat, Erygel, EES
Minocycline
Minocin (minocycline) chibereko chetetracycline chakashandiswa zvakajeka kwemakumi emakore sechirwere chemazino. Inonyanya kukosha kune pustular type acne. (Pustule ipusti ine vesicle yakafanana ne whitehead yakakomberedzwa nehutsvuku.) Kunyange zvazvo kunyanya kweminocycline kunoderera nezvokudya, hazvirevi sezvinonzi kuderera kunoonekwa ne tetracycline. Iyo inowanzotanga chiyero ichi 50 kusvika 100 mg kaviri pazuva. Majoka makuru emigumisiro eminocycline inosanganisira dutu, kusuruvara, kurutsa, ganda rekuchenesa, uye dzino dzinochinja. Ganda uye dzino dzinochinja zvinowanzoonekwa kune vanhu vakatora minocycline kwenguva yakareba.
Minocycline (uye inoretically chero chibereko chetetracycline) inofanira kudziviswa mune avo vari kushandisa Acutane (isotretinoin) sezvo kusanganiswa kweizvi kunogona kuita kuti mamiriro ekuwedzera kuwedzerwa mukati mehenya ( pseudotumor cerebri .)
Doxycycline
Doxycycline inowanzoshandiswa kune vanhu vasingateereri kana kuti havagoni kushivirira erythromycin kana tetracycline, kana kune avo vangave vakaoma ne "hapana zvokudya" zvetetracycline (zvakadai sevechiri kuyaruka.) Muyero we doxycycline watanga pa 50 kusvika 100 mg kaviri pazuva. Inofanira kutorwa nechingwa; zvisinei, zvinogona kukonzera kushungurudza kukuru.
Doxycycline inowanzoita kupfuura tetracycline kuwedzera kunzwa kwezuva kana kukonzera kupisa kwezuva, chimwe chinhu chinonzi photosensitivity . Kune dzimwe mishonga yemishonga inogona kukonzera photosensitivity zvakare, zvakadai sebhenzoyl peroxide, alpha hydroxy acids, uye mapepa ekutenda.
Doxycycline inowanikwa pasi pezita iri mazita: Doryx, Oracea, Monodox, Atridox, Morgidox, Vibra-Tabs, Alodox, Ocudox, Doxy, Acticlate, uye Vibramycin.
Mamwe maantibayoti: Septra / Bactrim uye Macrolides
Septra kana Bactrim (sulfamethoxazole / trimethoprim) uye Zithromax (azithromycin) macrolide, kazhinji yakashandiswa kurapwa zvakaderera kusvika zvakanyanya kupisa acne. Zvidzidzo zvenguva pfupi hazviratidzi kufarira mushonga unorwisa mabhakitiriya kune mumwe nemamiriro ezvinhu aya, asi kurapwa kunoita sekushanda zviri nani kana zvichibatanidzwa nehutano hwemashoko. Allergic reactions (" sulfa allerergy ") yakanyanyojairika ne sulfanomides uye kushorwa kwakanyanya kwakaratidzwa nezvose izvi zvikamu zvemaantibioti.
Nhepfenyuro Inorwisa Antibiotics
Clindamycin inobatsira zvikuru semishonga inorwisa mishonga yemakumbo, asi inonyanya kutaurwa seyanoti maantibiotic. Chiyero chekutanga chinosvika 75 kusvika 150 mg kaviri pazuva. Nhengo huru yechipamamycin therapy inonyanya kukanganisa utachiona hunonzi pseudomembranous colitis inokonzerwa nebhakitiriya, Clostridium difficile . Chirwere cheClostridium difficile chinonyanya kuwanzana nemuromo we clindamycin asi yakataurwa nechokugadzirwa kwemashoko. Nyanzvi yemapurisa clindamycin inowanikwa seCleocin-T, Clinda-Derm, Clindagel, Makumbani, C / T / S, uye Evoclin.
Migumisiro Yechiri
Mishonga yose inorwisa mabhakitiriya inogona kukonzera vaginal mbiriso zvirwere kuvakadzi. Tetracycline inoratidzika kuva mishonga inorwisa mabhakitiriya inowanzowanzova nemigumisiro iyi. Zvose zvinorwisa mishonga inorwisa mabhakitiriya inogonawo kuderedza kubudirira kwemishonga yekudzivirira kubata pamuviri, saka avo vari kutora mishonga inorwisa mabhakitiriya vanofanira kushandisa nzira yekudzivirira kuberekwa. Nausea inowanzojairika ne erythromycin uye doxycycline. Zvakakosha kutaurira dermatologist yako chero ipi zvayo inogona kugadzirisa migumisiro pamwe chete kana iwe unofanirwa kudana nehupi zviratidzo.
Antibiotic Resistance
Mumakore achangopfuura tave tichiona kuwedzera kukurira kwebhakitiriya Propionibacterium acnes kurwisa mishonga inorwisa mabhakitiriya inoshandiswa. Nhasi mazano ekuderedza kusagadzikana (uye naizvozvo, kusava nemigumisiro yemishonga inorwisa mabhakitiriya pamusoro pemapurisa) inokurudzira kushandisa maantibayoti pamwe chete nemishonga yemazamu uye kupedza nguva yekushandiswa kana zvichibvira.
Pasi Payo Pamusoro Pemazwi Nezvokurwisa Antibiotics yeAgne
Mishonga inorwisa mabhakitiriya inogona kubatsira zvikuru kune vamwe vanhu vane acne uye vanoshanda nekubatanidza nzira. Mimwe mishonga inorwisa mabhakitiriya inoshanda zviri nani pamhando dzakasiyana dzehutema uye dermatologist yako inogona kuita sarudzo yakanakisisa kuburikidza nokunzwisisa nhoroondo yako yemakone uye mararamiro ako. Sezvo nemishonga ipi zvayo, migumisiro inogona kuitika. Nenzira yekuti kune zvisarudzo zvakasiyana-siyana zvinowanika kana chimwe chepamusoro chisingabatsiri. Mishonga inorwisa mabhakitiriya inowanzoshandiswa pamwe chete nemishonga yepamusoro uye kunyatsochengetwa kweganda zuva reganda rakagadzirirwa .
> Sources:
> Adler, B., Kommehl, H., naA A. Armstrong. Antibiotic Kurwisa muAcne Treatment. JAMA Dermatology . 2017 Jun. 21. (Epub mberi kwekudhinda).
> Wellenfeld, A., Nagler, A., uye S. Orlow. Oral Antibacterial Therapy for Acne Vulgaris: Kuongorora-Kubva Kuongorora. American Journal of Clinical Dermatology . 2017 Mar 2. (Epub pamberi pekudhinda).
> Descamps. V. Mishonga Inotungamirirwa Nekutungamirirwa kweAgne Vulgaris. JAMA . 2017. 317 (2): 213.
> Weller, Richard PJB, Hamish JA Hunter, naMargaret W. Mann. Clinical Dermatology. Chichester (West Sussex): John Wiley & Sons Inc., 2015. Print.