8 Mitauro yePergestin muKutakura Kuzvarwa Pills

Hormonal madhara inopesana ne progestin

Zvose zvinosanganiswa kuberekwa kupedza mapiritsi zvine estrogen (kazhinji ethinyl estradiol ) uye imwe yemarudzi masere eprogestin. Izwi rokuti progesin rinoshandiswa kune chero ipi zvayo yepanyama kana yevanhu inogadzirwa zvine zvinhu zvakafanana neprogesterone chaiyo. Progestin inoratidzwa nechizvarwa, chinongoratidza chete kana chichiendeswa kumusika uye kwete musiyano mumakemikari avo kana maitiro avanoita.

Kuti unzwisise zvakanakisisa kuti progestin inogona kuiswa sei, zvinobatsira kutsanangura mhando dzemigumisiro yeprogestin inogona kuva nechechikadzi :

• Progestational madhara anobatsira kudzivirira kuvharidzira uye kuderedza kubuda kwemwedzi kunopa ropa.
• Uyerogenic zvinowanzoonekwa seasingadiwi migumisiro yakadai seyamapfu uye muviri wehudzi hukura.
• Estrogenic madzimai inowanzoenderana nehuwandu hwe ethinyl estradiol mumapiritsi. Izvi zvinobatsira kubvisa zvinokonzerwa ne androgenic.

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Norethindrone

Norethindrone ndiyo progestin yechizvarwa chekutanga inowanikwa mune monophasic, biphasic uye triphasic formulations. Icho chiri nechokuita progestational uye zvishoma estergenic basa. Iko kunowanzova ishoma uyerogenic kupfuura yechipiri-generation progestins (levonorgestrel uye norgestrel), asi yakawanda uyerogenic kupfuura inonzi progestins idzva, sa deogestrel. Muchikamu chechidiki (chero piritsi iri pasi pe 50 mcg ye ethinyl estradiol), iyi progestin inovandudza mapurogiramu epodhi nekurera HDL nekuderedza LDL cholesterol.

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Norethindrone Acetate

Norethindrone acetate inonzi progestin yepasi peprogestational basa uye zvishoma isrogenic migumisiro. Ndiyo progesin yechizvarwa chokutanga. Iyo inowanzova ishoma uyerorogenic kupfuura progestin yechipiri-chizvarwa, asi yakawanda uyerogenic kupfuura inonzi progestins idzva, sa deogestrel. Chiratidzo Estrostep chakanga chakagadzirirwa kunyanya kufanana nemukadzi wekuzvarwa kwemwedzi nekupa huwandu huwedzere hwewesrogen neine progestin dose nguva dzose. Ndiyo mararamiro ega matatu oga neprogesin iyi. Izvi zvinogona kubatsira vakadzi vanoona zviduku zvinokonzerwa neserogen zvakadai seyeusea, migraines , kana kuchengetedza mvura pamwe nemamwe mapiritsi akabatanidzwa.

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Ethynodiol Diacetate

Ethynodiol diacetate inotangira chizvarwa cheprogestin chepakati progestational basa. Iyo ine zvinyorwa zvishoma zveesrogenic uye zvishoma uyero androgenic. Ethynodiol diacetate inobva kune norethindrone, saka inoshandurwa nyore nyore ku norethindrone mukati memuviri. Kurasikirwa kwepiritsi inosanganisira ethynodiol diacetate inowanzobatanidzwa nekuwedzera munguva yekutanga kana pakati pepurogiramu kuputika nekubuda ropa uye kuonekwa kana ichienzaniswa nemamwe mapiritsi ekubatanidza. Kunyange zvakadaro, maestrogen epamusoro anokwanisa kupikisa mukana wekubuda ropa , saka mapiritsi emapiritsi ane mazinga makuru eestrogen anogona kuderedza izvi.

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Levonorgestrel

Levonorgestrel inonzi wechipiri progestin uye ndiyo inonyanya kupiwa progestin yekudzivirira pamuviri munyika yose. Iine progestational yakakura uye uyerogenic migumisiro. Levonorgestrel zvinoshungurudza zvinokanganisa serum lipoproteins. Nhamba shoma shoma yesrogen marina ane progestin iyi inowanikwa. Levonorgestrel kuberekwa kwakave zvakare FDA inogamuchirwa nekukurumidza kubata pamuviri (zvakadai seChirongwa B Chimwe Chete uye Next Choice ). Iyo FDA yakataura kuti yose yekubatanidza mapiritsi neprogesin iyi yakachengeteka uye inobudirira pakubata pamuviri kwekukurumidza pasi peYuzpe method. Iyo FDA yakagamuchirawo marongerwo matatu emapiritsi emapilisi anoshandisa iyi progestin-Seasonale, Seasonique , uye Lybrel .

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Norgestrel

Norgestrel (chizvarwa chechipiri progestin) inosanganiswa yezvose zvisingaiti uye inoshanda isomer-dextro-norgestrel (haina kushanda) uye levonorgestrel (biologically inoshanda). Norgestrel ine high progestational uye yakasimba antiestrogen inowanikwa apo ichive yakakwirira mumabasa e androgenic.

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Desogestrel

Desogestrel inonzi progesin yechizvarwa chechitatu ne high progestational selectivity, kuderedza uyerogenic zvinokonzera uye isrogenic basa. Zvinoratidza kuipa kwakanyanya kunokonzera metabolism, kuwedzera kuwanda, mazinya, nezvimwe zvinokonzera zvinoratidzirwa nehuwandu hwemashuga. Inoratidza zvakakosha pa lipoprotein sezvinoratidzwa nekukwira zvishoma kweHDL cholesterol. Mishonga yemakiriniki inoratidza ngozi inogona kunge yakakwirira yehutachiona hwehutano husingafadzi ne desogestrel mapiritsi pamwe nevaya vane levonorgestrel. Mircette (low-dose estrogen / desogestrel pill) inopa nzvimbo yefupi placebo, iyo inogona kubatsira kune vakadzi vane migraines, dysmenorrhea , kana zvimwe zvinhu zvisina kunaka mukati mevhiki iyoyo. A low estrogen / maitiro ezvimwe zveestogestrel matatu, Cyclessa, inowanikwawo.

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Norgestimate

Norgestimate, chizvarwa chechitatu chinonzi progestin, ine purogiramu yepamusoro yeprogestational apo ichiratidza zvishoma zvinyorwa zveesrogenic uye zvinowanzova zvishoma uye androgenic. Iyo inewo zvishoma zvishoma pane serum lipoproteins uyewo pamakinhydrate metabolism. Izvozvo zvakashata uyerogenic zvinokonzerwa norgestimate zvakaguma nekubudirira kurapwa kwezvinyuchi. Zvechokwadi, mapiritsi ekuberekwa kwepabonde ane zvinyorwa zvachose ndeye chete FDA inobvumirwa kubatsira kubatsira kuderedza maitiro. Ortho Tri-Cyclen Lo igadzirwa rinopa norgestimate uye pakati pezinga-degree yeestrogen. Saka piritsi iyi inogona kubatsira mukudzikisa migumisiro yakadai seyeusea uye kurutsa asi isingakonzere kuwedzera kwekucherechedza (zvinowanzobatanidzwa nechepasi-estrogen mapiritsi).

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Drospirenone

Drospirenone ndiyo chete progestin yakabva kuna 17a-spirolactoneis. Inobatsira kudzivisa kuchengetedza kwemasmoni anodzora mvura yemuviri uye electrolytes. Icho chinewo pasi uyerogenic basa. Drospirenone uye estrogen inoratidzika kuderedza zviratidzo zvinobatana nekanyoro PMS (kuwedzerwa kudya, kushaya mafungiro, nekuchengetwa kwemvura). Drospirenone inogona kukonzera yakakwirira ye potassium, saka vakadzi vane tsvete, chiropa, kana adrenal chirwere havafaniri kuishandisa. Zvigadzirwa YAZ neBeyaz zvine mazuva makumi maviri nemaviri emishonga inoshanda uye mazuva mana emapiritsi e placebo. Iko kusanganiswa kunogona kukonzera kushanduka kwehomoni kushoma kudarika mapiritsi mapiritsi. YAZ zvakare yakave FDA-inogamuchirwa kubatsira kubata chirwere chekare chinokonzera dysphoric uye kubata chirwere chemaitiro mukati mevakadzi vane makore gumi nemana zvichikwira.

> Kwakabva:

> Progestin (Oral route, Parenteral nzira, Vaginal nzira). US National Library of Medicine. https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0011857/?report=details.