Chirwere cheCasgas chinotanga kuonekwa sechirwere chisingaregi, chirwere chinowanzoita sechirwere. Apo chirwere ichi chakaoma chechirwere chinogadzirisa, zvisinei, chirwere cheT. cruzi chinogona kuramba chiri mumuviri kwemakore akawanda, kunyange kuvanhu vanoita sehutano hwakakwana. Makore mazhinji gare gare, kazhinji mushure memakumi emakore, chimiro chisingaperi chine chirwere cheChagas chinogona kukura, zvichibereka matambudziko emwoyo, matambudziko emimba, kana maviri.
Zviratidzo zvechirwere zvechigas zvinoenderana nekuoma kwechimiro chakaoma chechirwere uye kana munhu ane utachiona akazopedzisira aita chimwe chemaitiro ekupedzisira echirwere chacho. Chirwere ichi chinokonzerwa nehutachiona nehutachiona hweprotozoan hunonzi Trypanosoma cruzi (T. cruzi), iyo, iyo yakazopararira kune vanhu nekurwara kwehutatu.
Chagas chirwere chinonyanya kuonekwa kumaruwa rweLatin America. Munharaunda iyo yenyika, ndicho chikonzero chikuru chekufa kwemwoyo, uyewo nekuremara kubva kumwoyo nematumbo.
Acute-Phase Zviratidzo
Mushure mekunge munhu ave akataridzirwa naT. cruzi, vanogona kurwara chero kupi kwevhiki kusvikira kumwedzi inoverengeka gare gare.
Flu-Sekurwara
Vanhu vakawanda vane maitiro akaoma eChagas chirwere havana zvimwe zviratidzo kana zviratidzo zvishoma. Vanogona kukudziridza zviratidzo zvakadai semafuta-kufanana kusanganisira fevha uye myalgia (kurwadziwa kwemuviri).
Kunyange zvazvo zviratidzo izvi zvinogona kuramba zvakadaro kwenguva yakareba semwedzi mishomanana, vanhu vazhinji vane chirwere chinotyisa chechigas havatombokumbira rubatsiro uye havazivi kuti vane Chagas.
Chagoma
Vamwe vanhu vane chirwere chakaipa cheChagas vanoita nzvimbo yekuramba ichidzimba nekuputika panzvimbo yekurumwa kwehutatu inorwara, kakawanda kumeso maziso kana kune imwe nzvimbo pachiso. Ichi chinozivikanwa sechagoma, uye kana ichizivikanwa, chinhu chinokosha chinonzi Chagas chirwere chinogona kuvapo.
Matambudziko
Muchikamu chiduku chevanhu-vashoma kupfuura 1 muzana-chikamu chakaoma chechigas chirwere chinogona kukura kuva chirwere chakakomba zvikuru. Vanhu ava vanogona kukura myocarditis (kuputika kwemutsipa wemwoyo), pericardial effusion , meningitis , uye / kana encephalitis . Kufa kwehutano hunobatanidza nehutachiona huno hutachiona hwechikamu chechigas chirwere chakakwirira kwazvo.
Late-Phase Symptoms
Kana imwe nguva yakaoma yeChagas chironga resolves (kazhinji mukati mavhiki gumi nemaviri ekutapukirwa kwokutanga), vanhu vanotapukirwa naT. cruzi vanopinda chikamu chisingaperi chechirwere. Kunze kwekuti munhu ane chirwere chinotyisa chechigas chinokonzerwa nekurapa nemishonga ye antitrypanosomal, chirwere cheT. cruzi chinogara chiri mumuviri nekuda kwehupenyu hwomurwere.
Chikamu chisingagumi chechirwere chaCasgas chakakamurwa kuva maitiro maviri: Fomu isina kugadziriswa, uye fomu inogadziriswa.
Fomu Indeterminate
Anenge wose munhu ane utachiona naT. cruzi uyo asingabatwi panguva yechikamu chechirwere ichi achapinda muhupenyu husingaperi hwechirwere kwemakore akawanda-makore anenge 10 kusvika ku30. Munguva yechikamu chisingaperi, hapana zviratidzo zvachose. Zvisinei, hutachiona hunoramba huchiripo, uye chirwere chinoramba chiripo muropa.
Izvi zvinoreva kuti vanhu vane chimiro chisina kugadziriswa chechirwere chirwere chinotarisa uye chinonzwa chiine utano hwakakwana chinogona kupfuurira chirwere kune vamwe neropa rekupa kana chipo chemuviri. Uyewo, vakadzi vane pamuviri vanogona kutora T. cruzi kusvika kumwana wavo nekutapurika kwepasplacental.
Kusvika makumi manomwe kubva muzana yevanhu vanotapukirwa naT. cruzi vacharamba vari muhutano husingaperi hweChagas kweupenyu hwavo hwose, vasina kumboita zviratidzo zvakare.
The Determinate Forms
Pashure pemakore gumi kana kupfuura ekurarama nehuwandu hwechigarire chechigas chirwere, kusvika 30 kubva muzana yevanhu vanotapurirwa naT. cruzi vachazopedzisira vachiratidzira chimwe che "mafungiro" echirwere chacho.
Iko kune maitiro maviri makuru ekugadzirisa chirwere cheChagas: chirwere cheCargas uye chirwere cheAgasta chirwere.
Chagas Heart Disease
Chagas chirwere chemoyo chimiro chechirwere chema cardiomyopathy , umo mwoyo unowedzera kuedza kubhadhara kushaya simba kwemutsipa wemwoyo. Pakupedzisira, kushaya simba kwemoyo kunotungamirira kumoyo kukanganisa . Somugumisiro, vanhu vane chirwere chemwoyo cheCasgas vanowana huwandu hwezviratidzo zvinowanikwa kune avo vane mwoyo kusakundikana. Izvi zvinosanganisira:
- Dyspnea (kukurumidza kufema). Dyspnea kazhinji inowanzooneka yakajeka zvikuru nekushingaira, asi inogonawo kuitika apo yakarara pasi ( orthopnea ), kana ichikomberedza ( bendopnea ), kana kuti inogona kukonzera kushamuka kubva pakudzika hope ( paroxysmal nocturnal dyspnea ).
- Edema . Kufuridza kwemakumbo, uye zvichida zvemuviri, kazhinji kunoguma kubva mumvura uye munyu kuchengetedza kunoitika nekunetseka kwemoyo.
- Kushaya simba uye kuneta. Kuderedza mwoyo kusvetuka kwekodha kunogona kukonzera kukundikana kukuru uye kuneta.
- Lightheadedness. Lightheadedness inogona kuitika kubva pakuderera kwemwoyo kunokonzerwa nekushaya simba kwemutsipa wemwoyo, kana kuti chironga chemwoyo .
- Palpitations. Chirwere chemwoyo chinowanzobatanidzwa nemoyo kusakundikana kunowanzoita kuti pave nemapapatendi.
- Syncope . Kurasikirwa kwekuziva kunogona kukonzerwa nehutano hwemwoyo arrhythmias.
- Stroke. Stroke inobatanidza nekunetseka kwemoyo chero ipi zvayo, nekuda kwekuwedzera kwechikonzero chekuvhara ropa.
- Kungoerekana kwafa. Kungoerekana kwafa kufa kubva kune tricycardia kana kuti ventricular fibrillation inowanzoshungurudzika kune vanhu vane mwoyo wekukundikana.
Chagas Gastrointestinal Disease
Utachiona hwehupombwe hunokonzerwa nehutachiona husingaperi hweT. cruzi hunojairika kupfuura hutachiona hwemwoyo uye hunokonzera rufu zvishoma nezvishoma. Zvisinei, maitiro emuviri weChagas anogona kuita zviratidzo zvakaoma uye anogona kuita kuti hupenyu hwezuva nezuva huve hwakaoma zvikuru. Zviratidzo izvi zvinowanzobatanidza:
- Nausea uye kurutsa
- Dysphagia (kunetseka kumedza)
- Odynophagia (kumedza kunorwadza)
- Gastrointestinal reflux
- Kuvhiringidza kwakanyanya
- Megacolon uye megaesophagus. Zvakafambiswa Chagas chirwere chemuviri chirwere chinogona kutungamirira kumusimba, kupiswa kweflakid yekoloni (megacolon) kana sopopus (megaesophagus). Mune zviitiko izvi, zviratidzo zvekuvharirwa kana dysphagia zvinogona kuoma zvakanyanya sekuve kutyisa upenyu.
Aya maitiro emimba anovhiringidza chero munhu, asi kuoma kwezviratidzo izvi kune vanhu vane chirwere chaChagas kunogona kusvika pakukwirira kukuru uye kunogona kuva kwakaoma kurapa. Izvozvo maitiro ezvirwere zvechirwere chisingaperi zveChagas zvinogona kuva nemigumisiro inokuvadza muupenyu hwemunhu.
> Sources:
> Cardoso RN, Macedo FY, Garcia MN, et al. Chagas Cardiomyopathy Inobatanidza Nekuwedzera Kwakawanda Kwekurohwa: A Meta-Analysis Of Observational Studies. J Khadhi Inokundikana 2014; 20: 931.
> Rassi A, Rezende JM, Luquetti AO, et al. Clinical Phases Uye Mafungiro eChagas Disease. Mune: American Trypanosomiasis (Chagas Disease): Makore zana Emakore Okutsvakurudza, 1MuEd, Telleria J, Tibayrenc M (Eds), Elsevier, Burlington, Ma 2010. P.709.
> Sabino EC, Ribeiro AL, Salemi VM, et al. Chiitiko Chegumi Gumi Chagas Cardiomyopathy Pakati peAymymomatic Trypanosoma Cruzi-Yakasimbiswa Yekare Vanhu Vopa Ropa. Circulation 2013; 127: 1105.