Kubatanidza huviri hwepamusoro-hwe-hutambudzo huripo
Kazhinji, vanachiremba vanoedza kukonzera kupera kwepurofesa kana kuti kuvepa kwako kune mishonga yakawandisa kana kuti yakawandisa. Nokudaro, kana iwe uchiuya nehuro yakawanda inoda mishonga inorwisa mabhakitiriya, uchawana mishonga yemhando imwe yemishonga inorwisa mabhakitiriya kwete mishonga yemarudzi akawanda emishonga inorwisa mabhakitiriya. Asi izvi zvinotungamirirwa here kune mishonga yepamusoro-in-marwadzo, zvakare?
Zvimwe NezvePolyrmacy
Zvikonzero zvekudzivirirwa kwepakati pepakati pakati pechiremba ndezvizhinji.
Chokutanga, kunyanya kushandisa mishonga yaunotora, inowedzera mungozi yemigumisiro yakaipa kana kushandiswa kwezvinodhaka-zvinodhaka. Kusiyana kwemishonga kunogona kuwirirana nenzira dzakawanda dzengozi.
Chechipiri, kana zvichibvira, chiremba anoedza kupa mishonga inobata chirwere uye inotangira mudzi wezvirwere. Kuwanda kwevematongerwo enyika kazhinji kunomiririra kupararira kunoshandiswa kugadzirisa zvirwere zvechirwere pane kugadzirisa chirwere icho pachako.
Chechitatu, sezviri munyaya yemishonga inorwisa mabhakitiriya, polypharmacy inogona kuisa njodzi kuhutano hwevanhu. Kunyanya, kutora mishonga inorwisa mabhakitiriya panguva imwechete uye kusapedza mwedzi wekurapa kunowedzera mukana wekuti mabhakitiriya asingagadzirwi nemishonga achapararira pakati pehuwandu hwevanhu. Bhakitiriya inopesana nemishonga inhau dzakaipa nokuti dzinorambidza kurapwa nemishonga inorwisa mabhakitiriya.
Chimwe chete kunze kwehutungamiri hukuru hwekudzivirirwa kwe polypharmacy ndiko kushandiswa kwepakati pemamwe mishonga inorwadza seye acetaminophen (Tylenol) uye ibuprofen (Motrin).
Iyi mishonga haipindirani. Uyezve, kurapwa kwemarwadzo kwakaoma uye kubatanidza acetaminophen uye ibuprofen inogona kubatsira kuderedza kurwadziwa kwakanyanya nguva dzose pavanenge vachidzivirira mishonga yeopioid. Kushandiswa zvisina kufanira kwewapioid kuri kuwedzera, uye iye zvino tava kunetseka kwedambudziko reopioid.
Nyaya, maopioid imishonga ine zvinokuvadza zvinokuvadza zvinosanganisira kusuruvara kwekupera uye kushandiswa kushandiswa.
Uyezve, mamwe maopioid formulations akaita seVicodin kana kuti Norco zvose zviri zviviri hydrocodone-acetaminophen kusanganiswa, uye, naizvozvo, kana zvakatorwa neTylenol, maopioid idzi dzinogona kuiswa kune acetaminophen. Kunyanya acetaminophen kunogona kutungamirira kuchiropa kukuvara.
Tylenol
Tylenol inoratidzira yeanalgesic iyo inoshandura nzira yatinoona nayo kurwadziwa uye inoderedza kutonhora kwemitumbi yedu (kureva, antipyretic). Inowanzobatanidzwa pamwe nemimwe mishonga yekuvandudza marwadzo akasiyana-siyana.
Kunyange zvazvo chaiyo nzira yeTylenol isingafaniri kujekeswa, tinotenda kuti mushonga uyu unoshanda nekudzivisa cyclo-oxygenase (zvikurukuru COX-2). Nemhaka yokuti Tylenol yakagadziriswa muchidimbu nechiropa, vanhu vane chirwere chechiropa vanofanira kudzivisa ichi chemishonga kana zvichibvira.
Motrin
Motrin inonzi nonsteroidal anti-inflammatory drug (NSAID), iyo, yakafanana neTylenol, inobata migumisiro yayo pa cyclo-oxygenase saizvozvo inhibisa prostaglandin synthesis. Prostaglandins inobatanidza kurwadziwa, kuputika, uye fever.
Kuvhiringidzika mu prostaglandin zvinokonzerawo vasoconstriction uye kuparara kwechirwere chinogona kutungamirira kushaya mafungiro. Nokudaro, vanhu vane matambudziko eminyo vanofanira kusiya pachena kuMotrin.
Pane imwe nhoroondo yakafanana, mune dzimwe, Motrin inogonawo kukonzera zvironda zvemudumbu uye kubuda ropa.
Kubatanidza Vaviri
Zvinofadza kuti, kunyange zvazvo iri tsika yakajairika, tsvakurudzo shomanana yakaitwa kuongorora kubatanidzwa kweTylenol naMotrin.
Zvimwe zvekutsvakurudza kwokutanga pamusoro pehurukuro zvakaitwa kuvana. Zvisinei, zvakaoma kukwevera correlates chaiyo pakati pemarwadzo uye kuponeswa kwefivha muvana kana ichienzaniswa neyevakuru. Kunyanya, vana vanorayirirwa vose Tylenol neMotrin nokuda kwekutambudzika uye fever vanowanzopiwa mishonga iyi semamwe maitiro.
Migumisiro yedzimwe chidzidzo chechidiki chakabudiswa muBritish Journal of Anesthesia inoratidza kuti kana Tylenol neMotrin zvichitorwa pamwechete (muchimiro chekuumbwa kwakanzi Maxigesic) nevarwere vakanga vachangobva kuvhiyiwa nemuromo, kusangana uku kunoguma mukurudzirwa kwakanyanya.
Saizvozvowo, zvinokonzerwa nekuongorora kwakagadziriswa kuongorora miitiro yakarongedzwa-yakarongwa uye yakabudiswa muPain Medicine inoratidza kuti "kusanganiswa kweparacetamol [acetaminophen] neNSAID yakashanda kupfuura paracetamol kana NSAID chete mu 85% uye 64% yezvidzidzo zvinoenderana, maererano."
Pasi Pasi
Saka zvinoita sekuti-kusiyana nekusanganiswa kweAspirin neMotrin , iyo iyo yose NSAIDs-kutora acetaminophen uye ibuprofen pamwe chete yakachengeteka uye inoshanda.
Asi usati waita zvido zvekurwadziwa kwako, ndinoenda kunokodzera mhinduro iyi nematatu matatu.
Kutanga, kana uine zvinetso zveropa kana zveputsvo, haufaniri kutora acetaminophen kana Motrin (kureva, NSAIDs), maererano.
Chechipiri, ma-analgesics akadai seTylenol kana kuti Motrin anogadzirirwa kushandiswa kwenguva pfupi bedzi. Ndapota yeuka kuti kurwadziwa hakusi chiratidzo chete asiwo chiratidzo chekukuvara kana chirwere. Kana marwadzo ako achienderera mberi, unoda kuona chiremba.
Chechitatu, iwe unogona kudarika zvose zveTylenol naMotrin saka zvichiita kuti ive imwe pfungwa yakanaka yekuita mishonga yakafanana yemishonga inoongororwa nachiremba.
> Sources:
Borazan NH, Furst DE. Nonsteroidal Anti-Inflammatory Drugs, Zvirwere-Kuchinja Antirheumatic Zvinodhaka, Nonopioid Analgesics, & Zvinodhaka Zvinoshandiswa muGout. Mu: Katzung BG, Trevor AJ. eds. Basic & Clinical Pharmacology, 13e . New York, NY: McGraw-Hill; 2015. Yakasvika muna Gumiguru 11, 2015.
Cliff KS et al. Kubatana neParacetamol (Acetaminophen) neAinsteroidal Anti-inflammatory Drugs: A Qualitative Systematic Review yeUbudirira hweAntgesic for Acute Postoperative Pain. Pain Medicine . 2010. > https://doi.org/10.1213/ANE.0b013e3181cf9281
Merry AF et al. Akabatanidza Acetaminophen naIbuprofen nekuda kweRuin Relief Pashure Pokuvhiya Murairo muVakuru: Randedzed Controled Trial. British Journal yeAnesthesia . 2010. https://doi.org/ > 10.1093 / bja / aep338
Olson KR. Chitsauko 4. Acetaminophen. Mu: Olson KR. eds. Kutyisa uye Kuwedzerwa Kwemishonga, 6e . New York, NY: McGraw-Hill; 2012.