Kuyevedza muviri uye rheumatoid Arthritis Treatment Inogona Kubatsira
Iwe unogona kunge wakawana izwi rokuti sarcopenia paunodzidza nezverheumatoid arthritis. Chaizvoizvo chinonzi sarcopenia, uye nei uchifanira kufunganya nezvayo? Ndezvipi matanho aungatora kuti ubatsire kutarisa?
Chii Chinonzi Sarcopenia?
Nenzira yakawanda, sarcopenia inokonzera kukanganisa kunowedzera kwe skeletal muscle tissue. Inogona kutaridzirwa sechimiro chemisi inoparara .
Pakutanga vatsvakurudzi vakashandisa izwi kurondedzera kusvibiswa kwemisumbu iyo inowanzoitika panguva yekukwegura yakazara asi munguva pfupi yapfuura, vamwe vatanga kushandisa izwi kurondedzera kushungurudza kwemisumbu iyo inogona kukonzerwa kana kuipisisa nezvimwe zvirwere, zvakadai se rheumatoid arthritis . Kuenzaniswa nevanhu vasina rheumatoid arthritis, vanhu vane rheumatoid arthritis vanowanzosangana nematambudziko anoshaya izvo zvinoitika pakutanga muupenyu. Izvi dzimwe nguva zvinonzi rheumatoid sarcopenia.
Kazhinji Masimba Anoshandisa
Iwe unoshandisa maronda emakumbo kuti uite mafambiro okuzvidira emakumbo ako, torso, uye zvimwe zvikamu zvemuviri wako. Izvo tsvina dzemafupa dzinoumbwa nemunhu akareba masishu. Aya mafivha ane mapuroteni chaiwo anogona kukwevera zvakasimba kuti arwisane kuti avhare misumbu, kana kuti akasununguka kuti mitambo iwedzere. Vanopindura zviratidzo kubva kune-neuron (uye pakupedzisira kubva muuropi) kukurega iwe uende muviri wako.
Mamwe masero ari mumutsipa anoshanda kugadzirisa kushandiswa kwemazuva ose uye kusveta pamasumbu, naizvozvo hazvikodzeri nguva.
Kuchinja muSarcopenia
Mu sarcopenia, kuchinja kunowanikwa mukati memusinga:
- Mimwe yemisipiresi inotanga kuchenesa.
- Mimwe tsvina yemasumbu inorasikirwa nehukama hwavo neuroni.
- Tsvina yemasumbu inoderera muhukuru hukuru.
- Tsvina yemisumbu inoderera nhamba yehuwandu.
- Zvimwe zvepurotini zvinoshandiswa mumusimba musangano zvinotanga kuputsika, uye masero ekugadzirisa magetsi haashande pamwe nekugadzirisa.
- Mimwe tsvina inogona kushandiswa nemafuta.
Zvinetso kubva kuSarcopenia
Nemhaka yeizvi zvose, mutsara unova muduku. Hazvishamisi kuti izvi zvinogona kutungamirira kumatambudziko akawanda, kusanganisira zvinotevera:
- Kupera simba kwesimba
- Kuremara kwakakura
- Kuwedzera kwekukanganisa
- Zvose zvakaderedza hupenyu hwehupenyu
- Kuenzanisa kwakashata
- Kuwedzera kwengozi yekuwisira kukanganisa (iyo inogona kunge iri kutyisa upenyu)
Chii Chinokonzera Sarcopenia?
Sarcopenia inoitika senhengo yekukwegura, kunyange kune vanhu vasina rheumatoid arthritis. Pakave nemakore gumi nematanhatu ehupenyu, vanhu vazhinji vakarashika kusvika makumi mashanu kubva muzana yemasimba avo ekutanga. Zvinhu zvakawanda zvakasiyana zvinogona kuita basa mukurasikirwa uku, kusanganisira:
- Kuramba mune mamwe mahomoni
- Yakachinja mafungiro emasikirini
- Inoderedza nhamba dzemaviri emasero
- Kudya kwakashata
- Kuderedza basa remuviri
- Kuwedzerwa kusingaperi kusuruvara
Kuvhiringidza Kunokonzera Sarcopenia muRheumatoid Arthritis
Kuvhiringidza chinhu chinonyanya kukonzera sarcopenia kuvanhu vane rheumatoid arthritis. Munguva yekuputika, mamwe masero emumunwe emuviri anosunungurwa ekuvhiringidza kytokines .
Izvi zvinonyatsojekesa mamolekoro anokonzera kupopota kwemuviri mumuviri. Iyi mhinduro inokonzera kukanganisa kwemisasa inowanikwa kune vakwegura vakuru.
Mu rheumatoid arthritis, mhinduro iyi inopesana inowedzera. Masero omusununguko anosunungura makuru akawanda ekuvhiringidza magytokines akadai se interleukin 6 (IL-6) uye tumor necrosis factor-α (TNF-α). Pakupedzisira, idzi cytokines dzinobatsira zviratidzo zve rhumumidhi arthritis sekurwadziwa pamwe chete uye kupfugama. (Ichi ndicho chikonzero mamwe mishonga inoshandiswa kurapa rheumatoid arthritis, yakadai seN TNF-inhibitors , yakagadzirirwa kubatsira kudzivirira ma cytokine aya.)
Izvi zvinokonzera kuvhiringidzika kune zvimwe zvinokonzera, kusanganisira kuwedzera kwemisimba kuputsika. Ndokusaka vanhu vane rheumatoid arthritis vangave vachida kutanga-sarcopenia uye zvakanyanya sarcopenia. Pakati pevarwere vane rheumatoid arthritis, vanhu vane zvikwata zvakakwirira zveiyo cytokines inoputira vane mungozi mukuru wekuva sarcopenia uye kuderera kwemasimba ane simba.
Zvimwe Zvimwe Zvinokonzera Sarcopenia muRheumatoid Arthritis
Nhamo pachayo chimwe chinhu chinoita kuti kuwedzere njodzi ye sarcopenia kune vanhu vane rheumatoid arthritis. Kana usina kutambudzika uye kusuruvara kubva muurumatoid arthritis, unogona kudzivisa kuita basa rinowedzera zviratidzo izvi. Nokufamba kweizvi izvi zvinogona kukonzera rudzi rwemisumbu inrophy inonzi disuse atrophy . Zvinyorwa zvishoma, izvi zvakaderera kukura kwemasisita inoitika apo musuru hauna kuwana nguva yakakwana yekurovedza muviri.
Vanhu vane rheumatoid arthritis vanogonawo kunge vari kushandisa mapurotini akawanda uye makoriyori kudarika zvinowanzoitika nekuda kwehosha yavo. Sezvo puroteni inodiwa kuti musikana kugadziriswa, izvi zvinogonawo kuderedza rheumatoid sarcopenia.
Kuongororwa kweRumatoid Sarcopenia
Bvunza chiremba wako kana une dambudziko pamusoro pekuderedza simba remasumbu nekuda kwerheumatoid arthritis. Chiremba wako anogona kushandisa zviratidzo zvakasiyana kuti aone kana iwe unogona kunge une sarcopenia. Izvi zvinogona kusanganisira zvinotevera:
- BIA kuedza (bioelectrical impedance analysis)
- DEXA test (maviri-simba X-ray absorptiometry)
- Miedzo yekuongorora simba remaviri uye kushanda kwese kwenyama
BIA ihwo hutachiona husingaoneki hunoshanda kuburikidza nekutumira pasi yakadzika kwazvo ikozvino kuburikidza nemuviri. Mhando dzakasiyana dzemaviri dzinodzikisa kupfuurira kusvika kumadhigirii akasiyana. Kubva pakurwisana kunoratidzika kwechigadzirwa ichi, magetsi anogona kuenzanisa kukosha kunonzi "fat-free mass" (FFM) iyo inogona kushandiswa kuongorora masimba.
Imwe nzira ndeye test DEXA (inowanzoshandiswa kuongorora osteoporosis). Ichi chimwe chiedzo chisina matambudziko chinoshandisa X-ray ine uwandu hwemhepo yakadzika. Muchiitiko ichi, inogona kushandiswa kuverenga kukosha kunonzi maonda muviri mashoma (LBM), imwe chiyero chemasisita mashoma.
Chiremba wako angakukumbirawo kuti uite mabasa akasiyana-siyana, zvakadai sokufamba nokukurumidza kana kufambisa chigadzirwa chechigamba.
Cherechedza kuti vanhu vane rheumatoid sarcopenia hazvirevi kuti vanorasikirwa nehutano hwemuviri. Mu rheumatoid sarcopenia, chikamu chemapuroteni emisipiresi chinogona kuchinjwa nemafuta. Nemhaka yeizvi, uremu hahugoni kuchinja zvikuru, kunyange kana munhu akarasikirwa nehutachiona hwemishupa. Ndicho chikonzero chimiro chemuviri wemuviri (BMI) haisi muedzo wakanaka we rheumatoid sarcopenia. Uyu muedzo hauongorori kana kuwanda kuri kuuya kubva musumbu kana kubva kumafuta. Vamwe vanhu vane rheumatoid sarcopenia vachave vakaderedza BMI, asi mune vamwe vanhu BMI inogona kunge yakajairika kana yakawedzerwa.
Rheumatoid Cachexia
Imwe mutauro unoenderana iwe unogona kunzwa rheumatoid cachexia. Cachexia inoreva mamiriro ekuremera kwakanyanya, mafuta, uye kurasikirwa kwematumbo kunoitika nekuda kwechirwere chikuru chechirwere, chakadai sekenza. Nenzira, vanhu vazhinji vane rheumatoid cachexia vanewo rheumatoid sarcopenia. Asi havasi vose vane rheumatoid sarcopenia vane rheumatoid cachexia.
Zvisinei, kunyange vanotsvakurudza havawanzoshandisa mazwi aya nguva dzose. Nyaya yacho inogona kuvhiringidza vose vanachiremba nevarwere, nokuti hutano hwehutano hahuna hutano hwakasimba hwekuongorora vanhu vane rheumatoid sarcopenia uye rheumatoid cachexia. Chikamu nekuda kweizvi, isu hatina kuongororwa kwakanaka kwekupararira kwemamiriro aya. Isu tinoziva kuti varwere vazhinji vane rheumatoid arthritis vane zvishoma nezvishoma kushaya simba kweutema.
Kudzivirira uye Kuchengetedza Rheumatoid Sarcopenia
Vatsvakurudzi havana kutora mazano akajeka ekurapa rheumatoid sarcopenia. Zvisinei, nyanzvi dzinoona nzira mbiri dzehutano nekudzivirira:
- Kugadzirisa zvirwere zvirwere zverheumatoid arthritis pachayo.
- Tsvaka nzira yakakwana yekushanda muviri.
Kuchengeta rheumatoid arthritis pachayo iri pasi pesimba ndeimwe yezvinhu zvakanakisisa zvaunogona kuita kudzivirira nekubata rheumatoid sarcopenia. Zvinodhaka zvakadai seN TNF-blockers uye IL-6 inhibitor zvinodhaka zvinogona kubatsira kuderedza kupisa kunowedzera rheumatoid sarcopenia.
Pari zvino, hapana zvakawanda zvekutsvakurudza pamusoro pekuti inguva iyi yekurapa kupora chirwere chinogona kubatsira kuvandudza sarcopenia kwenguva refu. Zvisinei, uchapupu hwechipiri hunoratidza kuti mishonga iyi inogona kubatsira.
Isu hatina dambudziko rakawanda rinofananidza kubudirira kwezvirwere zvakasiyana-siyana-kuronga anti-rheumatic drugs (DMARDS) mukurapa sarcopenia. Zvinonyatsozivikanwa kuti kurapwa kwenguva refu ne corticosteroids kunogona kuita kuti sarcopenia iwedzere. Nokufamba kwenguva, vatsvakurudzi vachadzidza zvakawanda pamusoro pezvipi zvirwere zvinorapa zvirwere zvingava zvakanakisisa kune varwere vane sarcopenia.
Kudzidzira Kurapa
Kudzidzira muviri ndiyo imwe chinhu chinokosha pakugadzirisa rheumatoid sarcopenia. Icho humwe hunoratidza kuti kudzivirira kushandiswa kunyanya kunogona kubatsira nezvose zvinotevera:
- Kuwedzerwa simba remaviri
- Kuderedza kuwanda kwechiito chechirwere
- Kuderedza kurwadziwa kwezvirwere
Zviremba, maitiro emisimba, kana muviri weumwe munhu pachake zvinogona kushandiswa kuita kuti misuru inoshanda zvakaoma kwenguva pfupi. Urwu ruzivo rwekudzidziswa simba rinogona kubatsira kudzivirira musero inrophy inoenderana nedheumatoid sarcopenia.
Uchapupu hunofananidzirawo kuti kubvumira kushanda muviri (zvakadai sokushambira) kunogona kuita basa rinodzivirira. Kumbira chiremba wako kuti akupe mazano mukuumba chirongwa chekuita basa. Unogona kuwana zvichibatsira kushanda nemudzidzisi wega kwechinguva.
Kuchengetedza chirongwa chekubatsira muviri nguva dzose kunogona kupa chimwe chipo kune vanhu vane rheumatoid arthritis. Chirwere ichi chinoratidzika chinokonzera kuwedzera kwehutano hwechirwere chemwoyo, asi chirongwa chekuita muviri nguva dzose chingabatsira kuderedza dambudziko rekurwadziwa kwemoyo uye zvinetso zvakafanana. Kudya kudya-utano hwakanaka kune mapuroteni akakwana uye makoriyori kunogonawo kubatsira kudzivirira rheumatoid sarcopenia.
Shoko Rinobva
Kutarisana nedheumatoid sarcopenia kunogona kukanganisa. Asi kuziva kuti uri panjodzi yekurasikirwa kwemasisipo kunogona kukurudzira zvakanyanya. Kuita kuti kuderedza sarcopenia kunetseke, chengetedza chirwere chako kuchengetedzwa zvakanaka nemishonga uye uite chirongwa chinogara chichiratidza muviri.
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