Ko chirwere chemuti chinonzi medullary chinopesana sei nedzimwe mazamu emukenza?
Medullary carcinoma yemazamu ndiyo maitiro asina kujairika emukenza wemazamu. Icho chimiro chekushaya ductal carcinoma (IDC) uye inotora zita racho kubva pamaronda aro, ari pedyo nehuputi hwehuputi tissue, kana medulla. Inotanga mumukaka wako wemukaka, uye makanda makuru ekenza anotarisa zvakasiyana zvikuru nemasero ane utano.
Medullary carcinoma haisi inowanzozivikanwa.
Medullary carcinoma inokwana 3 kubva muzana chete kusvika ku5 muzana yevamwe mazamu emukaka. Zvinogona kuva zvakaoma kusiyanisa kubva mumvura inopinda mumatope uye pane dzimwe kenza dzine zvimwe asi kwete zvose zvinosanganisira medullary carcinoma. Pamusana pekubatana kweizvi, vanachiremba dzimwe nguva vanobata medullary carcinoma zvakanyanya kukuvadza, zvichida, kupfuura zvaidiwa, dzakapiwa kunaka kwayo. Inowanzoonekwa kune vakadzi mumakore makumi mana ekupedzisira uye kutanga kwema50s.
Kuonekwa
Medullary carcinoma masero anowanzoita muganhu wakajeka pakati pemakumbo uye mhuka dzakanaka pedyo navo - dzinopinda mudiki pane dzimwe dzera dzemazamu. Pasi pema microscope, masero makuru uye asinganyanyi kuratidza uye ane utsinye, asi vanowanzorega kuita sechisimba sezvavanotarisa.
Pane kazhinji masero emunununu (semakiriniyte) pamakona emakumbo aya, zvichiratidza kuti maitiro ezvirwere zvemuviri anoshanda kurwisa chiremera.
Kana kenza yemazamu ine chitarisiko che medullary carcinoma asi haikwanisi zvose zvinotarisirwa, unogona kunzwa chinora chako chinonzi "atypical medullary carcinoma." Izvozvo zvinokonzera kanzira zvinowanzobatwa zvakafanana nezvimwe zvirwere zvekenza, mune mamwe mazwi, zvinotyisa.
Zviratidzo nezviratidzo
Medullary carcinoma yemazamu haangave nguva dzose inzwa sechimedu, asi, sepakangoita, nzvimbo yechipfuva yematehwe.
Inogona kutanga ichitaridzwa sekutambudzika, kubwinya, kana kuvhara mukati mako. Sezvo masero e medullary carcinoma akawandisa uye achida kugara pamwe chete nekuwedzera mune imwe nzvimbo, chironda chinogona kunzwa sechinotarisa-sachidi, sechristin yemvere . Ichi ndicho chikonzero chakakosha kuti uve nechirwere chiri muchipfuva chako chiongororwe, kunyange kana chinonzwa se cyst nyore.
Miedzo yeKutsvaga
Medullary mazamu emakwenzi haarati azviratidzira pane imwe mamamamiro uye anowanzotanga kuwanikwa apo mumwe munhu anonzwa bundu. Chifuva che ultrasound chinogona kuitwa pamwe chete. Nzira imwe chete yekusiyanisa medullary carcinoma kubva kune dzimwe mhando dzekenza yepamu inenge ichinyanya kuitika. Muenzaniso unowanzowanzoitwa nekuvhima yakazaruka kana kuti stereotactic breast biopsy .
Mishonga
Kazhinji medullary carcinomas iduku uye inogona kubatwa nyore nyore nekuvhiyiwa. Hazvishoma kudarika mamwe mazamu emumuromo ekupararira kune lymph nodes, uye vamwe vanachiremba vanoona kurapwa voga kuti zvive zvakakwana kurapwa kwemakumbo aya (akawanda ayo ari pasi pe1km muhukuru.) Zvirwere zvinogona kusanganisira:
- Kuvhiya : Kuvhiya kunoitirwa vazhinji vevanhu vane chirwere ichi chekenza yebonde uye inogona kunge ine lumpectomy kana kuti mastectomy , zvichienderana nechinzvimbo chechirwere uye zvaanoda.
- Chemotherapy : Sezvo vazhinji vezviremara izvi zviduku uye kazhinji zvisiri kupararira kune lymph nodes, chemotherapy inowanzodiwa chete kuti matumbu makuru kudarika masendimita muhukuru. Izvozvo zvakati, dzakawanda zvezvipembenene zvinoputika-zvine maitiro - emamwe marudzi ekenza yemazamu, uye naizvozvo inogona kurapwa zvakanyanya.
- Radiation therapy : Zvakare, therapy inonzi radiation inoshandiswa zvishoma kudarika kune dzimwe mhando dzekenza yemazamu, asi inogona kushandiswa mumatambudziko ega.
- Hormone therapy : Hormone therapy inoshandiswawo kakawanda ne medullary carcinoma, sezvakawanda zvezviremera izvi zvinonzi hormone receptor zvisina kunaka. Mune rumwe ruzivo, 68% yezviremara izvi zvakanga zvisina kunaka zvevhenekeri zveestrogen uye 86 muzana zvakanga zvisina kunaka kweprogesterone receptors.
- Herceptin inoshandiswa kazhinji nekiyu chekenza sezvo vazhinji vemaviri aya ari HER2 asina kunaka. Mune imwe yedzidzo inopfuura 80 muzana yemakumbo akanga asina kunaka kweHER2 receptors.
Prognosis
Medullary carcinoma inowanzova nekakwirira-grade kuonekwa masero anoshanda nenzira inononoka-kukura. Hazvikwanisi kupararira kune lymph nodes kupfuura mamwe mazamu emukaka uye zvakakwana zvine maitiro akanaka kwazvo. Mune rumwe ruzivo rwakakura, kuwedzera kwehuwandu hwemakore maviri kwaiva 98.2 muzana. Kudzokorora kunopfuura kweizvi zvakare kwakaderera zvikuru kana kuenzaniswa nedzimwe mhando dzekenza yemazamu.
Sources:
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Dieci, M., Orvieto, E., Dominici, M., Conte, P., And V. Guarneri. Kazhinji kenza yemazamu subtypes: histological, molecular, uye makiriniki anozivikanwa. Oncologist . 2014. 19 (8): 805-13.
Lim, S., Park, S., Park, H., Hur, M., O, S., uye Y. Suh. Prognostic Basa reAdjuvant Chemotherapy muNode-Negative (NO), Triple-Negative (TN), Medullary Breast Cancer (MBC) muKorea Population. PLOS One . 2015. 10 (11): e0140208.
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