Herceptin, inozivikanwa nezita rayo rokuti trastuzumab , inonzi chemotherapy infusion medication inogamuchirwa kupora kenza yemajosi eAdjuvant uye kenza yemazamu. Iyo inowanikwa puroteni inoshandiswa uye inosunga kuHER2 protein (vanhu epidermal growth factor receptor2). Vanenge 1 muvanhu 4 vane kenza yemazamu vane HER2-positive kenza yepamu kana proteine vanhu epidermal kukura factor receptor2.
HER2 chirwere chinotyisa chebonde chinokura nokukurumidza uye chinopararira nokukurumidza.
Overview
Adjuvant Breast Cancer uye Herceptin
Herceptin inobata kenza yepabonde pekutanga-inonzi HER2-positive uye inogona kana kuti isati yasati yasvika kune lymph nodes . Nekenza yemukondombera yeAdjuvant, Herceptin inoshandiswa sechikamu chekurapa panguva yechikemikari.
Metastatic Breast Cancer uye Herceptin
Herceptin anobvumirwa kubata chirwere chemastastatic breast mune nzira mbiri. Inogona kushandiswa mukubatana nechemotherapy mishonga paclitaxel kana inogona kushandiswa yoga kune varwere vakatove vakagamuchira chemotherapy nokuda kwekenza yavo yemazamu.
Iyo Inoshanda Sei
Herceptin chikamu chekirasi yemishonga inonzi biologic therapies. Ichi chinodhaka chinoshanda nekuvhima pasi chete iyo masero emukenza ane HER2 / neu receptors pane avo vari kunze. IHER2 gene inogadzira puroteni yakagadziriswa pamusoro penheyo yesero. Ichi chinogamuchirwa chinoratidza sero kugovana uye kuwedzera.
Kana paine HER2 yakawandisa mumapfupa ekenza yebonde, kupatsana kwemasero kunopera simba, kuchikura zvakakurumidza zvikuru. Herceptin inonamatira kune HER2 receptors uye inovhara chiratidzo chekukura, kudzivirira mamwe masero ekuparadzanisa uye kuderedza kufambira mberi kwekenza.
Icho chichena chakachena kana chikoro chemvura chinowanzochengetedzwa kuburikidza ne chemotherapy.
Administration
Herceptin inoshandiswa kuburikidza ne chemotherapy infusion. Nhamba yako yokutanga ichapiwa zvishoma nezvishoma mumutambo wemaminitsi makumi 90 kuti uone kuti iwe unoregererwa zvakadini nemishonga uye kuti utarise kugadzirisa kwemaitiro. Kana iwe uchiita zvakanaka naHerceptin, kukanganiswa kwako kunotevera kunogona kupiwa mumaminitsi makumi matatu emaminitsi.
Migumisiro Yechiri
Vamwe varwere vanogamuchira Herceptin nokuda kwekenza yepese vaiva nemigumisiro inotevera:
- Fever
- Kunzwa uchirwara kumudumbu mako (kusuruvara)
- Kuramba (kurutsa)
- Kugadziriswa kwekupindurwa
- Diarrhea
- Zvirwere
- Kukwidza kukwira
- Headache
- Kunzwa kuneta
- Kupfupika kwemhepo
- Mapundu
- Sero rekuchena uye rvuku reropa rinoverenga
- Uturu hunorwadza
Vamwe varwere vanogamuchira Herceptin nokuda kwekenza yemukondombera yakave nemigumisiro inotevera:
- Serosi yakachena yeropa rinotora
- Diarrhea
- Kunzwa kuneta
- Sero tsvuku tsvuku yeropa inotora
- Kuchema kwemukanwa kubatana
- Kuonda
- Kumusoro kwekupumha kwepamuviri zvirwere
- Fever
- Low platelet yakaverengwa
- Kufuridzira kwemucous membrane
- Kutamba kwemhino nehuro
- Shanduka muvira
Zviratidzo izvi zvinowanzoonekwa mumaawa masere ekugamuchira Herceptin.
Kana iwe uine chirwere chinokonzerwa neHerceptin, tumira chiremba wako pakarepo. Allergic zviratidzo zvinosanganisira kupera kwekufema kwakanyanya, kuputika, kuzvimba kwehuro kana miromo uye mikoko. Zviratidzo zvinokurumidza zvinosanganisira kupfupika kwemhepo uye kurwadziwa kwepfupa.
Ngozi
Herceptin inogona kukonzera matambudziko emwoyo uye congestive moyo kukundikana. Kuruboshwe kwako kwemhepo inofanirwa kuongororwa kunoda kuongororwa pakarepo usati watanga Herceptin, panguva dzenguva dzenguva dzese paHerceptin (purogiramu yemashoko ekutaurira ndeye mwedzi mitatu), uye pashure pokupedzisa Herceptin kurapwa. Ngozi yematambudziko emwoyo inowedzera kana uri kurapwa naAdriamycin uye Cytoxan uye Herceptin.
Usatora Herception Kana:
- Iwe uri allergiki kune Herceptin
- Iwe uri nepamuviri kana kunwisa
Zvinorayira Purogiramu
Vose oncologists vanokurudzira kuti urege kushandisa doro, fodya, kana caffeine munguva yekurapwa naHerceptin.
Caffeine inokonzera kuomeswa kwemashupu ako, izvo zvinongowedzera kuoma kunowanzokonzerwa nemishonga yako chemo. Taurira boka rako rehutano kana uri kusvuta fodya, doro kana kuti zvinodhaka, uye kukumbira rubatsiro mukurega kushandiswa kwemishonga iyi. Shandisa zvepabonde panguva yekurapwa naHerceptin, nokuti ichi chinodhaka chinogona kukuvadza mwana kana iwe wava nemimba. Kana iwe uchitova nepamuviri, iva nechokwadi chekuudza chiremba wako.
Self-Care Tips
- Gara zvakanaka-uchisimudzirwa nekunwa maviri kana matatu makiritsi emvura nguva dzose maawa 24
- Kana zvichidikanwa, tora mishonga yako inorambidza kunyorera sezvinorayirwa
- Vamwe varwere vanonzwa ucheche uye kugona, saka torai nyore kusvikira zviratidzo izvi zvichinyanyisa
- Kana uine zviratidzo zvakadai semaperembudzi, udimbu pamabheji uye unwe mvura zhinji (zvinwiwa zvemitambo zvinogona kubatsira)
- Mazino uye kurwadziwa zvinogona kubviswa neacetaminophen kana ibuprofen, asi chengeta nachiremba wako kutanga
- Zorora zvakakwana sezvaunogona
- Idya kudya kwakanaka, kunovaka muviri
Chinhu
FDA. Drug Information. Trastuzumab Product Label Details. Yakavandudzwa: September 2013.