Kunyange zvazvo pasina mushonga wePalinson's disease , pane mishonga yakawanda inowanikwa kubatsira kubatsira kudzora zviratidzo zvechirwere chinopfuurira.
Unoshandiswa uri woga kana (inowanikwa) pamwe chete, mishonga iyi inobvumira muviri wako kuti uite zvakanaka, iyo inobatsira iwe kuita zvinhu zvaunoda kana zvaunoda kuita.
Vanhu vane Parkinson vanogona kuzvibatsira nekudzidza nezvekushandiswa kwemishonga iyi, zvipi zvinobatsira zvavanogona kupa, uye mimwe migumisiro yechirwere yavanogona kuita. Zvino, apo chiremba wako anoratidza kuchinja kana kuwedzerwa pamishonga inenge uri kutora, unogona kuita chisarudzo chakanaka pamushonga wako.
Dopamine Replacement Therapy
Levodopa , kana L-dopa sezvinowanzozivikanwa, inonzi ndiyo yegoridhe yakarapwa yekurapa kwaPacinson uye ndiyo inowanzoshandiswa mishonga yemamiriro acho ezvinhu.
Mushonga wacho unoshandurwa kuva neurotransmitter dopamine muuropi, iyo inowedzerazve dopamine zvinhu izvo zvakarashika sezvo chirwere chinopfuurira. Nokuita kudaro, L-dopa inovandudza zviratidzo zvepachiratidzo chePalinson's disease.
D-dopa inoshanda zvakanyanya asi inogona kukonzera zvimwe zvinokonzerwa nemigumisiro, kusanganisira kutenderera kusingaiti (kunozivikanwa se dyskinesias). Inowanzotarisirwa pamwe chete nemumwe mushonga unonzi carbidopa unoderedza izvo zvinokonzera.
Dopamine Agonists
Yechipiri inowanikwa zvikuru-inoshandiswa mushonga wePalinson's disease ndeyodhaka inonzi dopamine agonists. Panzvimbo yekutora dopamine muuropi yako, zvinodhaka izvi zvinonyengera uropi hwako pakufunga kuti ine dopamine yakakwana. Mishonga iyi inoita izvi nekusunga kune zvinogamuchirwa zvinoreva dopamine muuropi.
Dopamine agonist inobatsirawo kuderedza zviratidzo zvemuti wePalinson's disease. Dzinogona kushandiswa dzoga kana kusanganiswa naL-dopa.
Nzira dzinowanzowanzoitwa dopamine agonist dzinosanganisira kushungurudza, kurutsa uye kudonha muropa. Vamwe vanhu vangava nemafungiro ekumanikidzika, kuisa njodzi pavanotora mishonga iyi, iyo inogona kuderedza kushandiswa kwavo.
MAO-B Inhibitors
Monoamine oxidase inhibitors - inozivikanwa seMaO-B inhibitors - yekutanga yakashandiswa semishonga yekuderedza, asiwo inobatsira mukurapa chirwere chePasinson. Iyo mishonga inovhara kuparara kwemuviri wako neurotransmitter dopamine muuropi yako, iyo inobatsira kuchengetedza dopamine kupa zvakakwirira uye kuderedza zviratidzo zvako zvePasinson.
I-MAO-B inhibitor inowanzoshandiswa muPasinsinson inosanganisira Eldepryl uye Zelapar (selegiline) uye Azilect (rasagiline). Vanogona kutarirwa voga kana nedzimwe mishonga yePasinson, uye migumisiro inogona kusanganisira kuora mwoyo, kushaya musoro, kuoma muromo, ucheche, kusuruvara uye kurasikirwa kwechido.
Vatsvakurudzi vakatarisa kana MAO-B inhibitor zvechokwadi inogona kuderedza kufambira mberi kwechirwere chePasinsin (pane kungovandudza zviratidzo), asi zvakagumisa hakuna uchapupu hweiyo. Kunyange zvakadaro, madhiragi anobatsira kurapa zviratidzo zveParkinson.
Zvimwe
Mimwe Mishonga
Kune mimwe miviri yemishonga inoshandiswa mukutsvaga kuwana kuti kuenzanisa kwakakwana kwekurapa kwemishonga nezvishoma zvisingabatsiri.
Rimwe boka remishonga rinonzi COMT inhibitors, somuenzaniso, rinogona kubatsira mamwe D-dopa kusvika pauropi nekudzivirira muviri kuti urege kuuputsa. Comtan (entacapone) uye Tasmar (tolcapone) mienzaniso miviri ye COMT inhibitors.
Symmetrel (amantadine) inoshandisa nekuwedzera huwandu hwe dopamine yakaitwa nemuviri wako nekudzivirira muviri wako kuti urege kuputsa dopamine iripo. Inoshandiswa mukutanga kwePasinson kuti inoratidze zviratidzo, uye inogonawo kubatsira nemafungiro asingabatsiri kubva kuL-dopa.
Anticholinergics yakadai seCogentin (benztropine) haisati yashandiswa asi inogona kubatsira vamwe varwere vaduku vaPasinson kudzora kudengenyeka. Vanotarisa imwe nyurotransmitter muuropi - acetylcholine.
Pakupedzisira, Exelon (rivastigmine), chirwere chechirwere chechirwere cholinesterase inhibitors, chinogamuchirwa kuitira kurapwa kwemaitiro muPasinson. Inogona kubatsira kuvandudza chiyeuchidzo chako nekushanda kwako kwezuva nezuva.