Nguva yakareba melanonychia ndeyekuvapo kwemutsara wakavezwa, unowanzo huvhuvhuta kana hutsvuku, pamwe nehurefu hwembambo yembambo. Izvo zvinowanzoitika kune vanhu vane ruvara rweganda. Longitudinal melanonychia inokonzerwa nekuiswa kwe melanin mumucheka wekupikira kubva kune zvakasiyana-siyana zvinokonzera. Nhamba shomanana yevanhu vane longitudinal melanonychia vane subungual melanoma .
Zvinokonzera
Pigment muzvipikiri zvako inobudiswa nemasero anonzi melanocytes mumubhedha wemisodzi. Dzinobereka melanin, iyo pigment inopa bvudzi rayo uye inobereka shisa yezuva paganda rako. Mumubhedha wechipfupa, vanotumira melanin kumasero ari kubudisa chipikiri. Paunoona mutsara werima mumisungo yako, ndiko kwavanoita kuwedzera melanini pachigadziko uye kunogadzira ruvara sezvo mbambo inowedzera kunze.
Zvinokonzera melanonychia zvakakamurwa kuva maitiro e-melanocytic activation, apo masero anenge atovapo anotanga kubudisa akawanda melanin, uye melanocytic hyperplasia apo mamwe majekiti anobudisa pigment achiwedzera.
Benign Zvinokonzera
Kazhinji kazhinji iwe uchaona rima rakasvibira musono rimwe chete. Muna 73% yevanhu vakuru vakuru, izvi zvinokonzerwa nemasero aripo ikozvino anowedzera kuwedzera pigment. Rudzi rweganda rako reganda chikonzero cheizvi, sezvo vanhu vane ganda renyama rakajeka vanowanzova nemabhanhire akareba akareba mumisungo yavo.
Iwe unowana zvakawanda sezvaunenge uchikwegura, uye zvinowedzera. Zvinowanzoitika pane zvigunwe zvaunoshandisa kubata zvinhu-chigunwe chako, chinyorwa, uye pakati peminwe.
Kubata pane imwe nguva iyo iwe unowanzoona marefu evereve melanonychia. Kutambudza kumapuranga echipikiri kunogona kukonzera zvakare. Kana iwe ukaona mitsetse pane zvigunwe zvako zvigunwe kana zvigunwe zvikuru, zvingave zvichibva pamakumbo ako achigunzva kupfeka shangu dzako kana asingakodzeri zvakanaka.
Utachiona hweFungal hwekupihwa hunogona kukonzera mitsara yakasviba, sezvinokwanisa psoriasis, hutachiona hweganda kumativi echipikiri, amyloidosis, uye lichen planus.Ingaonekwa zvakare, kazhinji nemapoka akawanda, muAdisonison's disease uye AIDS.
Chemotherapy, X-rays uye electron beam therapy inogona kukonzera melanocytic activation, kazhinji pamisungo mizhinji. Inogona kuonekwa muLaugier-Hunziker syndrome, Peutz-Jeghers syndrome, uye Touraine syndrome.
Melanocytic Hyperplasia-Benign uye Malignant Melanoma
Melanocytes inogona kuwedzera nekubudisa melanonychia mumamiriro ezvinhu akaipa kana akaipa. Bhenign hyperplasia inogona kuva mujenti (mavara) kana nevi (matendere). Muvana, 77.5% yematambudziko e melanonychia anokonzerwa nebenign melanocytic hyperplasia.
Malignant melanocytic hyperplasia inogona kunge yakakonzerwa nemaranoma inoparadza kana in situ. Inowanzowanzoonekwa muchigunwe, chikuru chetete kana kunyora munwe. Zvinowanzoitika kakawanda mumapoka emadzinza ose, apo maranoma mune dzimwe nzvimbo ndeyemhando dzemadzinza madema-mavara.
Miedzo yekuongorora
Kuti utonge maranoma, biopsy inowanzoitwa. Iyo yeputi inotora mhuka kubva mumatambo echipikiri, izvo zvinogona kukonzera kupera. Izvi zvingasava izvo zvaunoda, asi maranoma ndiyo chirwere chakakomba chinoda kurapwa.
Kunobva:
Julie Jefferson * uye Phoebe Rich. "Melanonychia." Dermatol Res Pract. 2012; 2012: 952186. Yakabudiswa paIndaneti 2012 Jun 27. nei: 10.1155 / 2012/952186. PMCID: PMC3390039