Nyaya inogadzirisa mvura, vitamini-B yakaoma iyo inokosha kumuviri kwemabasa akawanda kusanganisira kuumba masero matsva nekuita masero matsvuku eropa.
Inonzi chirwere kana ichiwanikwa muzvokudya, zvakadai semaruva, michero, nemiriwo mavara mashizha. Folic acid ndiyo yakagadzirwa nehutatu inowanikwa mune zvokudya zvakawanda zvakasimba (zvakadai sechingwa uye zviyo) uye sekuwedzera.
Vanhu vane chirwere chinokonzera chirwere chinokonzera chirwere (IBD) vari pangozi yekushayikwa kwevanhu, zvikuru avo vari kutora methotrexate kana sulfasalazine .
Chinoita Kuti Kukosha kweWorate
Muviri haugoni kuita mhando kana folic acid, saka inofanira kuwanikwa kubva pakudya uye kuwedzera. Nyaya ine vitamini B iyo inokosha kare uye panguva yekuzvitakura nokuti inoshandiswa mumasero ekusika nekuparadzaniswa. Kudya kwakakwana kwehupenzi kunoda kuchengetedza neural tube kasina kukwana sepina bifida mumwana.
Nyaya inofanirwawo kuti muviri uchengetedze zvakakwana mazinga eamino acid homocysteine, inodiwa nemuviri weprotini synthesis. Pasina folate yakakwana, homocysteine ichavaka mumuviri. High level of homocysteine inobatanidza nehutano hwepfungwa.
Nyaya inogonawo kubatsira kudzivirira kenza nekudzivirira dzimwe kuchinja mumuviri weDNA. Nemhaka yokuti upenzi hunodiwa kuumba masero matsvuku eropa, kuwana folate yakakwana kunokosha zvakare kudzivirira anemia .
Chikonzero nei varwere veBD vari panjodzi yekushayikwa kwevarume
Vanhu vane chirwere cheCrohn mumatumbo avo maduku vari pangozi ye malabsorption yemavhithamini akawanda nemaminera-folate akabatanidzwa. Nyaya inobatanidzwa nepakati uye chikamu chekupedzisira chemukati mudumbu, jejunum uye ileum.
Sulfasalazine uye methotrexate mishonga miviri inoshandiswa kurapa IBD iyo inogona kupindira ne metabolism ye folate.
Zvimwe zvikonzero zvevarombo zvisina kufanira zvinosanganisira kunwa doro, chirwere cheropa, uye kushandiswa kwemishonga anticonvulsant, metformin , triamterene, kana kubhakwa.
Munhu Wese Ane IBD Panjodzi Dzakakosha Here?
Chimwe chidzidzo chakaratidza kuti vatsva vakaongororwa vane chirwere chepachirwere vane hutsika hwakakosha kupfuura vana vasina vana IBD. Vanyori vakashamisika, vakapiwa kuti zvakasara zvakatsvaga chokwadi pakati pevakuru vechidiki IBD. Nhamba dzehutano muvana vane IBD dzinogona kuongororwa kuti dzione kana zvidimbu zvinowanikwa zvechokwadi.
Varwere veBIV vari pangozi yepamusoro yean homocysteine. Homocysteine is amino acid, uye mazinga ari akakwirira zvikuru anosanganiswa neropa rekuvhara uye kuora mwoyo. Mune vanhu vane IBD, kushayikwa kwevarume kunogona kana kusakanganiswa kwekodzero yakakwirira ye-homocysteine-uchapupu hunopesana. Kunyanya kuongororwa kumwe kwakaratidza kuti kuwedzera homocysteine kune vanhu vane IBD kunogona kuva nemigumisiro yakaderera ye vitamini B12, panzvimbo yepamusoro mazinga evanhu.
Zvaunogona Kuita
Kuti udzivirire kushaya uwandu, zvinogona kukurudzirwa kuti vanhu vane IBD vanotora supplement ye folic acid. Avo vanotora sulfasalazine uye methotrexate, kunyanya, vanogona kuwedzera mamwe folic acid. A folic acid supplement ye 1000 micrograms (1 milligram) pazuva inowanzokurudzira kune avo vari panjodzi yekushayikwa kwevanhu.
Tarisa nechiremba wako kuti uone kuti zvakadini folic acid iwe unoda zuva rega rega uye kana iwe uchida kutora chero zvigadzirwa.
Zvimwe zvekudya zvine folate kana folic acid ndezvi:
- Asparagus
- Nyuchi yemombe
- Broccoli
- Cowpeas
- Mbeu dzakasimbiswa, mupunga, mazai evha, uye chingwa
- Great Northern beans
- Green peas
- Sipinachi
Sources:
Crohn's uye Colitis Foundation yeAmerica. "Zvokudya uye Zvokudya." CCFA.org 29 Apr 2009.
Erzin Y, Uzun H, Celik AF, Aydin S, Dirican A, Uzunismail H. "Hyperhomocysteinemia mune chirwere chechirwere chechirwere chevarwere vasina chirwere chemuviri chakapfuura: kuwirirana ne cobalamin, pyridoxine, folate concentrations, acute phase reactants, chirwere chekuita, uye matambudziko epamberiembo . " J Clinic Gastroenterol 2008 May-Jun; 42: 481-486.
Heyman MB, Garnett EA, Shaikh N, et al. "Kuisa pfungwa muzvirwere zvevana vane hutachiona hwehutachiona hunenge huchangobva kuonekwa." Am J Clin Nutr 2009 Feb; 89: 545-550.
Office of Dietary Supplements. "Dietary Supplement Fact Sheet: Folate." National Institutes of Health 15 Apr 2009.
Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M. "Hyperhomocysteinemia uye chirwere chechirwere chechirwere: kupararira uye kufungidzira muchidzidzo chemukati." Am J Gastroenterol 2001 Jul; 96: 2143-2149.
Silaste ML. "Zvirwere zvinokonzerwa ne antioxidants, oxidised LDL uye homocysteine." Oulu University Library 2003.
Vagianos K, Bector S, McConnell J, Bernstein CN. "Kudya kunovaka muviri kwevarwere vane chirwere chinoputira chirwere." JPEN J Parenter Enteral Nutriti 2007 Jul-Aug; 31: 311-319.