Izvo zvinokonzera kukakavadzana, saka chengetedza matambudziko aya mupfungwa
Glucosamine is supplement supplement dzimwe nguva inoshandiswa kupedza marwadzo eguti osteoarthritis (OA). Pane imwe nguva yakakurumbira, kushandiswa kwayo ikozvino kwaderera, kunyanya nekuda kwemigumisiro yakavhiringidzika yakapoteredza kubatsirwa kwechokwadi kwekuwedzera.
Kana iwe ukatora glucosamine kana uri kutarisa muedzo wekuwedzera (pasi pekuchengetwa kwachiremba wako, hongu) apa pane mitsara mitanhatu yekuchengeta mupfungwa:
Tidbit # 1: Glucosamine Inowanzoonekwa muKartilage
Glucosamine chinhu chechisikigo (chinonzi amino tsukasi) inowanikwa muhutano hwakanaka hwechirwere uye synovial fluid , izvo zvose zvinokonzera majoini ako. Mu osteoarthritis, martilage inowanikwa mumapfundo ako anowedzera, zvichiita kuti utambure uye kuoma. Marwadzo acho anogona kunyanya kukura sezvinonzi cartilage inenge yakanyanya kureba zvokuti mapfupa anotanga kusungurudzirana.
Tidbit # 2: Glucosamine Haisi Kurongerwa seMishonga
MuUnited States, glucosamine inotengeswa sekuwedzera kwekudya. Izvi zvinoreva kuti inotungamirirwa neUnited States Food and Drug Administration (FDA) sechigadzirwa chezvokudya, kusiyana nemirairo kana mishonga inodhaka.
Nezvo, kunyange zvazvo glucosamine ari chikamu chechisikwa chetikiti, hazvirevi kuti kuitora kwakachengeteka zvakakwana. Ichokwadi, glucosamine inogona kuchinja mashuga eropa uye inogona kusangana nemimwe mishonga yakafanana neropa-rakapfava Coumadin (warfarin).
Sezvo nguva dzose, iva nechokwadi chokuti unongotora mushonga, kusanganisira zvinowedzera, pasi pekutarisirwa kwechiremba wako.
Tidbit # 3: Glucosamine Ingave Isingagoneki Knee yako Osteoarthritis
Kunyange zvazvo kutsvakurudza kweongororo pamaseroti akawana kuti glucosamine inogona kusimbisa regrowth of cartilage uye kubvisa zvinopisa zvinokonzera kukanganisa karoti, iyi laboratory data haina kushandurirwa muchipatara kubatsirwa.
Chidzidzo chekutanga chikuru muUnited States chakaongorora mhedziso yenguva pfupi ye glucosamine (pamabvi osteoarthritis) yainzi maitiro eGGIT (Glucosamine Arthritis Intervention Trial).
MuGGIT, vatendi vanopfuura 1500 vakapfugama maziso eheteoarthritis vakakurudzirwa kune rimwe remapoka mashanu ekurapa:
- Glucosamine pa 500mg katatu pazuva (zvikamu 1500mg pazuva)
- Chondroitin sulfate (uyewo zvokudya zvinowedzera kudya uye chikafu chechisikwa) pa 400mg katatu pazuva (1200mg pazuva)
- Glucosamine uye chondroitin sulfate pamwe chete
- Celecoxib (a nonsteroidal anti-inflammatory, kana NSAID) pa 200mg zuva nezuva
- A placebo (chinhu chisina kushanda)
Migumisiro inobva kuG GAIT yakaratidza kuti vatori vechiuto vanotora NSAID celecoxib vakawana ruzivo rwakakonzerwa nehutano hunoenderana ne placebo.
Kwakanga kusina kusiyana kukuru pakati pemamwe marapirwo akaedzwa uye placebo.
Kunyangwe, mune zvimwe zvevadzidzi vanenge vachidzidzira vane kurwadziwa kwakakomba-ku-kwakanyanya, glucosamine yakabatana ne chondroitin sulfate yakapa ruzivo rwakanyanya rwekurwadziwa kana tichienzaniswa ne placebo. Vatsvakurudzi vekudzidza, zvisinei, vakataura kuti nokuti ukuru hwechikamu ichi chakanga chiri chiduku, kuwanikwa uku kunofanira kufungwa sekutanga uye kunoda kusimbiswa mune zvidzidzo zvekutsvaga mune ramangwana.
Kune vanotora nemarwadzo emabvi akanyoro (kusiyana neanoenzanisa kana akaoma) glucosamine uye chondroitin sulfate pamwe chete kana kuti chete havana kupa chirwere chinorwadza chikuru.
Tidbit # 4: Kune Mhando mbiri dzeGlucosamine
Zvakakosha kuziva kuti glucosamine inogona kupiwa nemhando mbiri dzakasiyana dzemunyu, hydrochloride kana sulfate. Iko gait yekudzidza (yakataurwa pamusoro) yakashandisa glucosamine hydrochloride. Zvinofadza, zvidzidzo zvakaratidza zvimwe zvingave, kunyange zvazvo zviduku, zvakashandiswa glucosamine sulfate kupora osteoarthritis pane glucosamine hydrochloride.
Somuenzaniso, chidzidzo chikuru muInternational Journal of Clinical Practice yakatsanangura vanopfuura 3000 varwere vane knee osteoarthritis mukati memajeri 19 akasiyana.
Vanyori vekutsvakurudza uku vakapedzisa kuti glucosamine hydrochloride yakanga isingabatsiri mukuderedza kunetseka (kufanana neGeit trial).
Zvisinei, kukwirira kwe glucosamine sulfate (1500mg pazuva) kunogona kuva nemigumisiro yekugadzirisa kana inotorwa kwemwedzi inopfuura 6. Basa-kugadzirisa zvinoreva kuti glucosamine sulfate inogona kuvandudza kukwanisa kwevanhu kushandisa mabvi avo (kana mabvi) neosteoarthritis.
Tidbit # 5: Chii chinonzi American College of Rheumatology States Pamusoro peGlucosamine
Maererano neAmerican College of Rheumatology, kana ACR, vanhu vane maziso ehetrostearthritis havafaniri kushandisa glucosamine. Zvisinei, izvi zvinokurudzirwa zvakaitwa "zvakagadziriswa," sezvo ACR ichiziva kuti glucosamine ikozvino inopesana.
Pane kudaro, ACR inokurudzira zvinotevera pakurapa mabvi OA:
- Tylenol (acetaminophen)
- NSAIDs (zvichida nemuromo kana paganda rako)
- Ultram (Tramadol)
- Corticosteroid injections muchikamu chakabatana
Shoko Rinobva
Kunyange zvazvo chivimbiso cheglucosamine sechimwe chirongwa chemapfupa emabvi esteoarthritis hachina kunyatsobudiswa, vamwe vanhu vachiri kuitora uye vanoiwana inoshanda kwavari.
Pakupedzisira, pasinei nehutano hwehutano hwemabvi ako osteoarthritis, zvakakosha kuona chiremba wako achigara achizotevera. Nzira iyi unogona kugadzirisa kurapwa kwako sezvo hutano hwako huri pamwe hunobudirira uye kutsvakurudza kunoitika.
> Sources:
> Hochberg MC et al. American College of Rheumatology 2012 mazano ekushandiswa kwee nonpharmacologic uye pharmacologic therapies mu osteoarthritis yesimba, hip, nemabvi. Arthritis Care Res (Hoboken) . 2012 Apr; 64 (4): 465-74.
> Jerosch J. Migumisiro ye glucosamine uye chrondroitin sulphate pahutakiti metabolism muOA: Kutarisa kune vamwe vashandi vemuviri, kunyanya omega-3 fatty acids. Int J Rheumatol . 2011; 2011: 969012.
> National Center for Complementary and Integrative Health. (2014). Glucosamine uye Chondroitin yeOsteoarthritis.
> Wu D, Huang Y, Gu Y, Fan W. Kubudirira kwekugadzirwa kwakasiyana-siyana kweglucosamine pakurapa osteoarthritis: meta-kuongororwa kwemiedzo yakarongeka, inopofumadza, inonzi blindbo-controlled. Int J Clin Pract. 2014 Jun; 67 (6): 585-94.