Hepatitis B: Inogona Kukonzera Chirwere Chepfungwa Here?

Dzidza kuti sei Hepatitis B inogona kukanganisa mafungiro, uye chii chaungaita pamusoro payo

Chiremba anotenderera vakawanda anobvuma kuti chimwe chezvirwere zvinotsausa zvikuru mumenclatures kunze kweHpatitis B uye neHepatitis C-yakabatana nechiropa cheropa. Mazita acho haana kukwana kurondedzera zvirwere izvi kubva pane izwi rokuti "hepatitis" rinoreva kuputika kwechiropa. Izvi zvinopa pfungwa yokuti nhengo imwe chete inobatwa neHepatitis B kana C ndiyo chiropa, chinonyengera nokuti zvose zvezvirwere izvi zvinoona kubatanidzwa kwezvimwe nhengo kunze kwechiropa, uye naizvozvo zviratidzo zveve fide systemic (uye kwete nzvimbo) zvinotaura.

Inso imwe yechirwere chakadai kuti hepatitis virusi inobata zvose zvakananga uye zvisingaiti. Hepatitis virusi haisi yega inopindira iyo inogona kukanganisa mafungiro. Zvisinei, basa ravo mune zvirwere zvepfungwa zvakakosha kucherechedza zvakapiwa kuwanda kwepamusoro kwehutachiona hwehutachiona. Ngatitaurei mamwe mashoko nezvehutachiona hwehutachiona hwaHepatitis B.

Ndezvipi Zvakafanana Nekambani yeChinyi Dzaase NeHepatitis B?

Chirwere chepoyo nekuda kwehutachiona hweHepatitis B hunowanikwa kakawanda kune vanhu vanotapukirwa nehutachiona kana paucheche kana paudiki. Varwere ava vanowanzova "vatakuri" uye vanotakura chirwere chikuru chezvirwere zvepfungwa.

Nei Chirwere Cheropa Chichikuvadzai Ipi

Kunyange zvazvo inowanzofungidzirwa, kukanganisa kwepvo kubva muropa reHepatitis B haisi kazhinji chikonzero chehutachiona hwakananga. Kutaura zvazviri, kusagadzikana kwemaitiro ezvirwere zvezvirwere zvezvirwere zvezvirwere kune zvimwe zvikamu zvehutachiona zvinogona kuita basa guru mukurwara kwechirwere.

Izvi zvinowanikwa nehutachiwana zvinowanzosangana nekurwisana nemasikirini ako muchiedza kurwisana nehutachiona. Kana izvi zvikaitika, ma antibodies anozvisunga nehutachiona, uye zvipuka zvinokonzera zvichaiswa muinso. Iyo inogona kubva yakagadzirisa zvinopisa zvinopisa zvinogona kukonzera kuora kwepvo.

Nokudaro, panzvimbo yehutachiona zvakananga zvakananga nehvo, ndiyo mhinduro yemuviri wako iyo inotarisa maitiro uye chiyero chepfungwa yekukuvara.

Mhando dzeDiyo Disease Inokonzerwa neHepatitis B Virus Infections

Zvichienderana nehutano hwehupi hwehutachiona hwehutachiona uye kuputika kwechirwere chinoratidzwa pamusoro apa, zvirwere zvakasiyana zvepfungwa zvinogona kuitika. Heino mhedziso yekukurumidza:

1. Polyarteritis Nodosa (PAN): Ngatishandure zita iri kuva zviduku, zvipfeko zvekudya. Izwi rokuti "poly" rinoreva vazhinji, uye "arteritis" rinoreva kuvhiringidza kwemishonga / midzi yeropa. Iyo yekupedzisira inowanzonzi sevasculitis zvakare. Sezvo nhengo dzose mumuviri dzine mishonga yeropa, (uye iyo inora ine vasculature yakafuma), polyarteritis nodosa inoputika zvikuru nemidziyo yeropa (mune izvi, itsvo 'arteri) inobata midzi midzi ine midzi uye midzi yegori.
   
   Kuonekwa kwePAN kuvhiringidzika kunonyanya kufanana. Icho chimwe chezvirwere zvepfungwa zvekare zvinogona kuve zvichikonzerwa nehutachiona hweHepatitis B. Iko kunowanzokonzera vanhu vane makore ekumatana uye vakuru. Murwere anorwara acharamba achinyunyuta nezviratidzo zvisingaoneki zvakadai sokushaya simba, kuneta, uye marwadzo ekubatana. Zvisinei, zvimwe zvipembenene zveganda zvinogona kuonekwawo zvakare. Chiyero chebasa reimputi chicharatidza kusakanganiswa asi hazvirevi kuti chirwere ichi uye chirwere chepfungwa chinowanzodiwa .

1. Membranoproliferative Glomerulonephritis (MPGN): Uyu muromo-we-une-chirwere-nguva inoreva kuwandisa kwemasero ekuvhiringidza uye mamwe marudzi ezvinyama (pasi membrane munyaya ino) muinso. Zvakare, izvi ndizvo zvinopesana nekutapira pane kutaurira utachiona hwehutachiona. Kana uine Hpatitis B utachiona utachiona uye utanga kuona ropa mumuguta, ichi chinhu chinoda kuonekwa. Zviri pachena kuti kuvapo kweropa mumuguta hakusi kukwana kusimbisa kuongororwa kunyange kana une Hp B virus. Nokudaro, mimwe miedzo yakaisanganisira kusanganisa tsvina ingadai yakakosha.
2. Membranous Nephropathy: Kushandurwa mune chimwe chetsvo inonzi filter (inonzi glomerular pasi pemberi membrane) inotungamirira kune izvi. Vachirwere vachabatwa vachatanga kubudisa huwandu hwakawandisa hwepuroteni mumuguta. Somurwere, zvakaoma kutaura pamusoro pekuvapo kwepuroteni mumuguta kunze kwekuti yakanyanya kukwirira (pane izvozvi ungatarisira kuona kuputika kana sasi mumuguta). Ropa nderokutsvaga kuwana mumugini munyaya ino asi rinogona kuonekwawo zvakare. Zvakare, kuongorora ropa uye urini nokuda kwebasa rehso kucharatidza kusaremara, asi kusimbisa chirwere chacho, chirwere chepfungwa chichazodiwa.

1. HepatoRenal Syndrome: Chirwere chakaipisisa chepfungwa nekuda kwepreexisting chiropa chirwere chinhu chinonzi hepatorenal syndrome. Zvisinei, izvi hazvirevi hazvo kuHepatitis B dzine chokuita nechirwere cheropa uye zvinogona kuonekwa mune chero rudzi rwechirwere chinokonzera chiropa chinoshandiswa apo tsutsvo dzinogadziriswa nekuda kwezvikonzero zvakawanda.

Kuongororwa Hepatitis B Virus Associated Kidney Disease

Kana uine utachiona hunokonzera hepatitis B uye unonetseka kuti itsvo dzako dzingangodaro dzave dzichigadziriswa, unogona kuongororwa.

1. Zviri pachena kuti danho rekutanga nderokuita kuti uve nehutachiona hweH hepatitis B, iyo pane bhenja yakasiyana yeongororo iyo haifaniri kunge yakada tsvina yepso. Kana iwe uchibva kune imwe nzvimbo inozivikanwa kuva nehupamhi hwehutachiona hweH hepatitis B (endemic area), kana kuti ane ngozi yehutachiona hweH hepatitis B (kufanana kugovana nheyo dzevashandisi vezvinodhaka zveVV, iva nepabonde risina kudzivirirwa nevarume vakawanda zvepabonde, etc .), zvimwe zvinonzi bloodta test (testtale blood tests) zvinotarisa "zvikamu" zvakasiyana zvehutachiona hwe hepatitis B dzinogona kuve nekugona kusimbisa hutachiona.
   
   Kuongororwa kunoitwawo kune zvinorwisa muviri izvo muviri unopesana nehutachiona hweH hepatitis B. Mienzaniso yezviedzo zvinosanganisira HBsAg, anti-HBc, uye anti-HBs. Zvisinei, miedzo iyi inogona kunge isingakwanisi kusiyanisa pakati pehutachiona hwehutachiona (uko hutachiona huchikurumidza kudzokorora), kana hurumende (apo iwe paunenge uine hutachiona, hutachiona hunopera nguva refu). Kuti tione izvozvo, kuongororwa kweAIDS yeAIDS inokurudzirwa.
   
   Nemhaka yokuti zvirwere zviviri izvi zvinoitika kugoverana zvimwe zvinokonzera njodzi, kuongororwa kwemashure kwehutachiona hweH hepatitis C hungave husiri pfungwa yakaipa.
2. Danho rinotevera nderekusimbisa kuvapo kwezvirwere zvepvo, kushandisa sero rinotsanangurwa pano.
3. Pakupedzisira, chiremba wako achada kuisa vaviri pamwe chete. Mushure mokunge matanho maviri ari pamusoro apa apera, iwe uchiri kudikanwa kuratidzira chinetso. Nokudaro, tsvina yebipi ichave yakakosha kusimbisa kuti chirwere chetsvo zvechokwadi chinokonzerwa nehutachiona hweH hepatitis B, pamwe chete nemhando chaiyo yezvirwere zvepfungwa. Izvi ndezvokuti kungova nehutachiona hweH hepatitis B pamwe chete nehutano hwetsvo hazvirevi kuratidza kuti hutachiona hunotungamirira kukuvara kwepvo. Mumwe anogona kuva nehutachiona hweH hepatitis B uye ane ropa / mapuroteni mumuguta kubva pane zvakasiyana zvachose (funga, ane chirwere cheshuga ane dombo renso).
4. Chirongwa chekupedzisira kuongororwa uye chinokonzera ichocho chinonyanya kukonzera chirongwa chekurapa pamwe chete. Chirwere ichi chinotsanangurwa pamusoro (PAN, MPGN, nezvimwewo) zvinogona kuonekwa kune vanhu vasina hutachiona hwehutachiona hweH hepatitis B. Maitiro atinoita zvirwere izvi zvepfungwa zvinotaura mumamiriro ezvinhu aya zvichave zvakasiyana zvachose kubva maitiro avanoitwa kana zvichikonzerwa nehutachiona hweH hepatitis B.
   
   Zvechokwadi, mishonga yakawanda (yakadai se cyclophosphamide kana steroids) iyo inoshandiswa mukurapa kwete-hepatitis B-yakabatana neGPGN kana membranous nephropathy inogona kukuvadza zvakanyanya kupfuura zvakanaka kana zvichipiwa kumurwere ane chirwere che hepatitis B. Izvi ndezvokuti kurapwa uku kwakagadzirirwa kubvisa masimba ezvirwere zvemuviri, icho chinhu icho muviri unoda kurwisana nehutachiona hweHepatitis B. Kurapa nemafungiro ezvirwere mumamiriro ezvinhu aya kunogona kukonzera uye kunokonzera kuwedzera mukuzvinyorwa kwehutachiona. Nokudaro, kuratidza chikonzero ichikosha.

Inonzi Hepatitis B Inorwara-Inokonzerwa Nezvirwere Zvoutachiona Zvakaitwa Sei

Tora chikonzero chacho. Icho ndicho chinonzi crux chekurapa. Zvinosuruvarisa, hapana maitiro makuru maitiro anowanikwa kuti atungamirire kurapwa kwezvirwere zvepfungwa zvinokonzerwa nekuda kwehutachiona hweHpatitis B. Chero chero dhesi yatinayo kubva kune zvidzidzo zviduku zvidzidzo zvinotsigira kushandiswa kwehutachiona hwehutachiona hwehutachiona hwehutachiona hwehutachiona hweH hepatitis B sechirwere chekurapa.

1. Antiviral therapy: Izvi zvinosanganisira mishonga yakafanana ne-interferon alpha (iyo inoderedza kuwedzera kwehutachiona hweH hepatitis B uye "inogadzirisa" maitiro ezvirwere zvemuviri nehutachiwana), uye mamwe mazamu akadai sa lamivudine, entecavir, nezvimwe (iyo mishonga inoita kuti kuwedzera kwehutachiona zvakare ). Izvo zvipfeko zvakanakisisa pakurapa kusvika kure nekusarudzwa kwemujeri anoshandiswa (zvinowedzera zvichienderana nezvimwe zvinhu zvakadai sezera, ingave murwere ane cirrhosis kana kwete, muhutano hwenyiyo kukuvara, nezvimwewo). Ipi mishonga inosarudzwa ichaonawo kuti kurapwa kwenguva yakareba kunogona kupfuurirwa sei. Iyi hurukuro inopfuura kudarika kwenyaya ino uye inofanira kuva chinhu icho chiremba wako achakurukura newe asati atanga kurapwa.
2. Immunosuppressive agents: Izvi zvinosanganisira mishonga steroid kana mamwe mishonga ye cytotoxic se cyclophosphamide . Kunyange zvazvo izvi zvinogona kushandiswa mu "munda-siyana" chirwere chepfungwa chinonzi MPGN kana membranous nephropathy, uko kunoshandiswa hazvibvumirwi apo masangano aya ezvirwere anokonzerwa nehutachiona hweH hepatitis B (akapiwa njodzi yekuputira utachiona). Zvisinei, ichi hachisi "bhanhire rakarambidzwa." Pane zviratidzo zvakananga apo avo vashandi vangave vachiri kudiwa kuti vafunge kunyange mumamiriro ekurwara yehepatitis B. Imwe yakasiyana-siyana ndeyemhando yakakura kwazvo yokuputika kunobata maitsvo 'filter (inonzi inokurumidza kufambira mberi glomerulonephritis). Mune mamiriro acho ezvinhu, mishonga yemununosuppressive inowanzobatanidzwa nechimwe chinonzi plasmapheresis.

> Sources:

> Hepatitis B uye Renal Disease. Tak Mao Chan. Curr Hepat Rep. 2010 May; 9 (2): 99-105. Yakabudiswa paIndaneti 2010 Apr 14. ini: 10.1007 / s11901-010-0042-6

> Hepatitis B HIV-inosanganisira polyarteritis nodosa: kliniki maitiro, mugumisiro, uye kukanganisa kwehutano mu 115 varwere. Guillevin L. Medicine (Baltimore). 2005 Sep; 84 (5): 313-22.