Sweet's syndrome haisi chinhu chinonyanya kuitika chinosanganisira kuputika kunorwadza, kazhinji pamwe nefivha. Iko rinoputika zvikuru paganda remaoko, mutsipa, musoro uye mutsi. Chinokonzera Sweet's syndrome hachizivikanwe zvizere, asi kune zviitiko zvakasiyana-siyana zvinozivikanwa kuti zvinoitika.
Mune vamwe vanhu, zvinoratidzika kuti zvinokonzerwa nehutachiona, kana zvichida kubatanidzwa nehuputi hwehutachiona hwepamuviri nekuzvitakura; mune vamwe, inogona kuve yakabatanidzwa nekenza, kazhinji inenge yakaoma myelogenous leukemia; asi vamwe vane chimiro chinokonzerwa nezvinodhaka che Sweet's syndrome.
Sweet's syndrome inogona kubuda iri yoga, asi inowanzobatwa nemapiritsi etiroticosteroid, zvakadai sa prednisone. Sweet's syndrome inowanzonzi acute febrile neutrophilic dermatosis kana chirwere cheGomm-Button.
Zviratidzo
Sweet's syndrome inoratidzwa nezviratidzo zvinotevera:
- Fever
- Zviduku zvitsvuku zvakatsvuka pamakumbo ako, mutsipa, musoro kana mutumbi unokura nekukurumidza, uchipararira mumasumbu akaoma kusvika kumasendimita kana akaenzana
- Rash inogona kuoneka pakarepo mushure mefivha kana kuputika kwepamusoro .
Aina dze Sweet's Syndrome
Mamiriro acho anoonekwa nemhando mitatu yakasiyana:
Classical
- Kazhinji mune vakadzi vane makore 30 kusvika ku50
- Kazhinji inotungamirirwa nepamusoro yepamusoro yekutapukirwa kweutachiona
- Ingave yakabatanidzwa nekuputika kwechirwere chirwere uye pamuviri
- Inenge 1/3 yevarwere vane kudzokorora kweSweet's syndrome
Malignancy-Associated
- Ive mune mumwe munhu atozivikanwa kuti ane kenza
- Pangave mune mumwe munhu ane kenza yeropa kana chirwere chakasimba chisati chafukuzwa
- Kazhinji inowanzobatana nehutachiona hwemyelogenous leukemia , asi mamwe marariya anokwanisa, akadai sezamu kana kuti colon
Zvinodhaka-zvinokonzerwa
- Kazhinji kazhinji inowanikwa kune varwere vakambobatwa ne granulocyte-colony inokurudzira chinopiwa kukurudzira masero eropa rega
- Zvisinei, mamwe mishonga inogonawo kusanganiswa; Zvinodhaka zvakabatana ne Sweet's syndrome zvinosanganisira azathioprine, mamwe maantibhakitiriya uye dzimwe nhengo dzisina anti-inflammatory drugs
Kubatanidzwa Kunze Kweganda
Nokuda kwekusakanganiswa kweSweet's syndrome, zvishoma nezvinyorwa, uye maitiro akawanda anokwanisa kuitika, kwete zvose zvakawanikwa zvakabatana nechirwere ichi zvinobva kune chirwere chairo.
Izvozvo zvakati, Sweet's syndrome inofungidzirwa kuti ingangosanganisira mamwe maviri uye nhengo, kunze kweganda. Kubatanidzwa kwemapfupa nemafundo zvakanyorwa, sekubatanidzwa kwenheyo yenheyo-chirwere che "neuro-Sweet" chakatsanangurwa. Meso, nzeve, uye muromo zvinogonawo kuchinjwa. Mavhinga matsvuku anokwanisa kuwedzera kubva munzeve yekunze, kupinda mumugwagwa uye eardrum. Maziso anokwanisa kubatanidzwa, nekuputika, kubwinya, nekuputika. Zvironda pamusoro porurimi, mukati memasaya uye pamadziya zvinogona kukura. Kuvhiringidza uye / kana kuwedzerwa kwemuviri wemuviri nechifuva zvakare zvakataurwa.
Risk Factors
Sweet's syndrome haigoni kuitika, saka hutachiona hwacho hahufumi uye hunove huri humwe humwe zvirwere. Munowanzo, vakadzi vanowanzova ne Sweet's syndrome kupfuura varume, uye, kunyange zvazvo vakwegura uye kunyange vacheche vanogona kukura Sweet's syndrome, vanhu vari pakati pemakore makumi matatu nemakumi matanhatu ndivo vanonyanya kukanganisa boka rezera.
Uyezve, mamiriro ezvinhu anotsanangura mhando dzakanyorwa pamusoro apa angafungidzirwa kuti ane ngozi, saka Sweet's syndrome dzimwe nguva inobatanidzwa nekenza, inogona kuwirirana nekunzwisisika kune mamwe mishonga, inogona kutevera kuputika kwepachirwere chetachiona (uye vanhu vazhinji vanorondedzera kuva nehutachiona- sezvinoita zviratidzo zvisati zvaitika) uye zvinogonawo kubatanidzwa nehuputi hwechirwere chirwere, chinosanganisira Crohn's disease uye ulcerative colitis.
Vamwe vakadzi vakagadzira Sweet's syndrome panguva yekudzivirira zvakare.
Kuziva
Sweet's syndrome ingangodaro inofungidzirwa kana kuzivikanwa nokuongorora kupisa, asi, kuongororwa kwakasiyana-siyana kunowanzodiwa kuti kuongororwa uye / kana kutonga zvimwe zvikonzero.
Muenzaniso weropa rako unogona kutumirwa ku laboratori kuti utarise nhamba huru isina kukwana yemasero machena eropa uye kana kuvapo kwezvirwere zveropa.
Ganda rinoputika, kana kubviswa kwechidimbu chiduku cheganda rakagadzirirwa kuongororwa pasi microscope, inogona kuitwa. Sweet's syndrome ine unhu husina kunaka: masero ekuvhiringidza, masero machena emasero eropa emhando yeeutrophil, inopinda uye inowanzova mune imwe nzvimbo yepamusoro yechinhu chinorarama cheganda.
Nyaya dzinotapukisa dzinogona kubudisa zvakafanana pane zveganda, saka zvakaratidza kuti zvingave zvakachenjera kuti uvewo nemuenzaniso wakaedzwa mabhakitiriya, fungi, uye mavairasi.
Izvo zvinowanzogadziriswa ma laboratory zvinowanikwa nevarwere vane Sweet's syndrome zvakasimudzwa masero eropa eropa uye neutrophils muropa neropa rakakwirira ye erythrocyte sedimentation, kana ESR. Izvozvo zvakati, imwe yakachena yeropa rekuyera nhamba haisi nguva dzose inowanikwa kune vose varwere vane biopsy-yakagadzirirwa Sweet's syndrome.
Kurapa
Sweet's syndrome inogona kubuda iri yoga, isina kurapwa, asi mishonga inoshanda uye inoshanda nekukurumidza. Asingafungi, kupisa kunogona kupedza kwemavhiki kusvika kumwedzi. Mishonga inowanzoshandiswa ye Sweet's syndrome ndiyo corticosteroids . Nyuchi corticosteroids, yakadai sa prednisone , inogona kushandiswa, kunyanya kana mune dzimwe nzvimbo shomanana dzeganda dzakabatwa. Iyi mishonga is systemic, zvinoreva kuti inofamba mumuviri wose uye kwete ganda chete.
Mamwe maitiro e-steroid akadai seakrisheni kana mafuta anowanzoshandiswa pane zviduku, zvishoma zvishoma zvakapararira. Apo munhu ane Sweet's syndrome haabvumiri systemic corticosteroids kana ane zvinokonzera ne-long-term corticosteroids, kune mimwe mishonga inogona kushandiswa, yakadai se dapsone, potassium iodide, kana colchicine.
Varwere ne Sweet's syndrome vangava nezvinetso nekuda kwekubatwa kweganda, iyo Sweet's syndrome-inosangana nemamiriro ezvinhu, kana maviri. Chirwere chemajasitiri chinogona kushandiswa kana zvivara zveganda zvichibva kumhanyi zviri panjodzi yekuva nechirwere chechipiri.
Kuchenjerera kune chero chinetso cheSweet's syndrome-chinosanganiswa chingasvikewo chikamu chinokosha chekurapa Sweet's syndrome, pacharo. Semuenzaniso, zviratidzo zvinosanganiswa nehutano dzimwe nguva zvinokonzera kurapwa kana kurapwa kwechirwere chinoparadza.
Shoko Rinobva
Mishonga yakadai seye corticosteroids inogona kupa ruremekedzo kubva kune chirwere, asi kutarisa kumamiriro ezvinhu akabatanidzwa angavewo akakosha. Kana uine chirwere chinokonzerwa nemishonga che Sweet's syndrome, kana chirwere chinokonzera kukanganisa chave chichigadziriswa, chirwere chacho chinowanzo, asi kwete nguva dzose, chinovandudza uye chinowanzopa.
Zviri pachena, havasi vose vane Sweet's syndrome vane kenza; uye, pakudzidza nevanhu 448 vane Sweet's syndrome, 21 chete chete (kana 96 vevanhu 448) vakawanikwa vane hematologic malignancy kana chiremara chakasimba. Nyaya, zvisinei, ndeyekuti Sweet's syndrome dzimwe nguva inogona kutungamirira kuwanikwa kwekenza isingazivikanwe-uyewo kuti kudzokorora kwechirwere-chinosanganiswa Sweet's syndrome kunogona kuratidza kudzoka kwekenza.
> Sources:
> Cohen PR. Sweet's syndrome - kubvunzurudzwa kwakajeka kwehuwandu hwe febrile neutrophilic dermatosis. Orphanet J Rare Dis. 2007; 2: 34. doi: 10.1186 / 1750-1172-2-34.
> Hussein K, Nanda A, Al-Sabah H, Alsaleh QA. Sweet's syndrome (acute febrile neutrophilic dermatosis) inobatanidza neadenocarcinoma ye prostate uye transitional cell carcinoma yemukaka. J Eur Acad Dermatol Venereol. 2005: 19: 597-599.
> Sweet RD. An acute febrile neutrophilic dermatosis. Br J Dermatol. 1964; 76: 349-356. doi: 10.1111 / j.1365-2133.1964.tb14541.x.