Avodart uye Proscar ndeye FDA-inogamuchirwa kuitira kurapa migumisiro yemiginho kubva pakuwedzera kweprostate . Zita rechizvarwa re Avodart ndiro dutasteride; zita rechiito rePscar rinowedzera mari. Iyi mishonga, kunyange zvakadaro, ine mikana yakawanda yezviito pane kungosimudzira urinary basa. Dzinoshanda nokuvhara rudzi rwe testosterone runonzi dihydrotestosterone (DHT) inotarisa pa prostate, ichichikurudzira kuti ikure nekubereka mbeu.
Apo DHT yakavhara prostate gland inopera, inovandudza urinary flow.
Kune mimwe migumisiro yemigumisiro. Kubudiswa kwemanheru kunowanzoderedzwa. Dzimwe nguva varume vanotaura kuderedzwa kwe libido uye simba. Uyewo, kuwedzera kwepamu kunogona kuitika. Kazhinji, idzi migumisiro inopera ichapfeka kana kuderedza chero nguva iyo mishonga inomiswa pachiratidzo chokutanga chechinetso. Kunze kwekuvhenekera kunobatsira, pane imwe nguva yakareba yezvimwe zvinogona kubatsira.
Avodart kana Proscar vanogona:
- Lower PSA uye kuderedza dambudziko rekuongororwa nekenza yeprostate
- Kuvandudza kuonekwa kwehuwandu hwekenza yepamusoro yekenza yeprostate muvarume vanopinda biopsy
- Chikonzero Gleason 6 kenza (mukana wekenza-pasi-grade) kuti udzoke kana kuvharwa
- Kurudzirana nemimwe mishonga inoshandiswa kurapa kenza yeprostate yakadai seCasodex kana Lupron
- Batsira kuti varume varambe vachiongororwa uye vakaderedza dambudziko rekuvhiyiwa kunoda kana kuti kupiswa kwezuva
- Deredza kuderedza mhando yevarume
- Kurambidza kanagasm muvarume vane nguva isati yasvika
Anti-Cancer Migumisiro
Mune mhando yepamusoro yekuenzanisa Proscar ne placebo, varume gumi vakawana prostate biopsy mushure memakore manomwe ekurapa. Varume vePrescar-vakaporerwa vakaonekwa kuti vane kenza kanama 25% zvishoma kana ichienzaniswa nevarume vaitirwe ne placebo.
Zvisinei, kushingaira kwekushandiswa kweproscar nguva dzose kudzivirira kenza yakaderedzwa nokuti chidzidzo ichocho chakashuma 1% yakawedzera chiitiko chokuongororwa nekodhi-grade prostate kansa.
Nyanzvi dzenguva iyoyo dzakafunga kuti Proscar yakanga ichiwedzera kukura kwekuwana panzvimbo yekukonzera kukwirira kwepamusoro zvirwere. Zvisinei, Peter Scardino MD, murologist akakurumbira paChemberero Sloan Kettering akanyora pfungwa yokuti Proscar inogona kukonzera kenza yakawanda ine ngozi, inokwidza marudzi ese ekudengenyeka uye ichikurudzira FDA kuti ipe nyevero. Zvose izvi kutya zvakaguma zvadzingwa mumusi weAugust 15 th , 2013 weNew England Journal of Medicine iyo yakaratidza kuti hapana kuwedzera kwekenza yeprotate muvarume vaibatwa naPrescar vachienzaniswa nevarume vaibatwa ne placebo mushure mema18 ekucherechedza.
Kubva Avodart uye Proscar vachishanda nenzira yakafanana, zvakawanda zvezvizivikanwe nezvePscar zvinogona zvakare kutaurwa pamusoro pe Avodart. Zvose zviviri zvinoshandiswa kubata 5- alpha-reductase (5-AR), enzyme inoshandura testosterone muDHT. Pane inyanzvi yekuongorora ye Avodart pamusoro peProscar nokuti Avodart inodzivirira 5-AR enzyme zvimwe zvakanyanya. Kwete, kuongororwa kwekliniki, zvisinei, zvakaitwa kuenzanidza idzi mbiri majeri musoro kumusoro.
Sezvo zvose Proscar uye Avodart pasi pasi PSA inenge 50%, mubvunzo unomuka, "Vari kuvhara kukwanisa kwePSA kuratidza kufambira mberi kwekenza here?" Muchidimbu, mhinduro yacho kwete. Iyi mishonga haigadziri PSA pakusimuka kune varume vane kenza inopfuurira. Zvisinei, PSA inodzokorora panzvimbo 50% yepamusoro mushure mokutanga Proscar kana Avodart. Pakati pevhesi, murume ane PSA we 6.0 asati atanga Proscar ichasvika ku 3.0 mumwedzi mishomanana. Zvadaro, kana PSA inowedzera nguva dzose pamusoro pe03, kupfurikidza nekenza kunofanirwa kugamuchirwa sechikonzero chinokonzera.
Proscar uye Avodart vanowanzova nemigumisiro yenyoro uye kune vashomanana kana kusanganisa nemimwe mishonga.
Apo migumisiro yemigumisiro inoitika, inowanzove yakashandurwa. Proscar uye Avodart zviri nyore nokuti dzinogona kutorwa chero nguva yezuva, kana pasina kana kudya. Finasteride, generic yeProscar inowanika uye inonyanya kuwanika. Izvi zvinodhura mari uye rutivi rwepasiti yehutano inoita kuti zvive nechokuita nechokuita kune varwere vane kenza yeprotate vanoda kutsvaga PSA yavo vachiri kuchengetedza hupenyu hwakanaka hwehupenyu nemari shoma.