Angioedema inogona kuva nhaka, asi nguva yakawanda iyo isiri iyo. Ikoko kune zvirwere zvekuongororwa zvinogona kuziva kuti angioedema yakazvarwa.
Angioedema iyo isiri iyo inowanikwa inowanzoonekwa ichienderana nechitarisiko cheganda pamwe chete nenhoroondo yekutsvaga kune chinhu chinogona kunge chakaita kuti chirwere chisakanganise. Dzimwe nguva, kuongororwa kweropa kunogona kutsigira kuongororwa, asi zvigumisiro hazvive zvakananga maererano nezvisingaenzaniswi.
Kudzika-Cheki / Pamba-Kuedzwa
Iwe unogona kuzvitsvaga iwe kana mwana wako kuitira angioedema. Kazhinji, zviratidzo zvaunotarisa zvinonyatsooneka pamusoro peganda, saka haufaniri kuitsvaga.
Zviratidzo zvaunogona kutarisa zvinosanganisira:
- Dzorera miromo
- Dzorera meso
- Kutamba kwemaoko kana makumbo
- Kufuridzira rurimi rwako kana kumashure kwehuro pako
- Kusatarisira kusingatarisirwi mune chero chikamu chemuviri
- Kusvibiswa: Kufuridzira kwe angioedema kunowanikwa pamusoro peganda uye kunoratidzika kunetseka. Kazhinji, pane ruvara rutsvuku kana ruvara kana ruzha zvakare.
- Blanching: Iro reddish discoloration inowanikwa ne angioedema blanches. Blanching inotsanangura chimiro cheganda rakagadzirirwa kuti rive rakacheneswa kwemaminitsi mashomanana paunenge uchirikurira uye wozodzokera kumucheka wayo kana mutsvuku.
Imwe nzira yekucherechedza kana iwe kana mwana wako ane angioedema ndotarisa mazita ezvigadzirwa zvezvokudya zvakagadzirirwa zvawakapedza, kana zviine chimwe chinhu iwe kana hama yako yepedyo yave yakararisa kune yekare.
Labs uye Miedzo
Kune miviri miviri mikuru ye angioedema-rudzi rwenhaka uye rudzi rusina nhaka. Zviratidzo zvakafanana, asi kuongororwa kwekuongorora kunosimbisa rudzi rumwe nerumwe rwakasiyana.
Angioedema Iyo Haisi Hereditary
Kazhinji, angioedema iyo isiri nhaka ndeyekuongororwa zvichienderana nekuongororwa kwachiremba wezviratidzo zvako, kuongorora kwako kwepanyama, nekuzivikanwa kwechirwere.
An allergen chinhu chinokonzera simba rekudzivirira immune.
Miedzo inowanzoshandiswa mukuongorora kwe angioedema inosanganisira:
- Allergy Test: Kune marudzi akasiyana-siyana ekuongororwa kwemazuva ose . Iyo yakawanda inowanzobatanidza ganda duku rinoputika nechinguva chiduku chezvinhu zvinenge zvichifungidzirwa kuti zvinokonzera kurwisa. Kana iwe uine mhinduro yakadai sehukundu, kumanikidzika, kupfugama, kana kuchenesa munharaunda yepakutanga, iwe unogona kunge uine utano hwezvinhu. Unogona kuongororwa zvinhu zvakasiyana panguva imwechete, uye kana iwe unopindura kune imwe uye kwete vamwe ichi chiratidzo chakasimba chekurwisa.
- Kuedza Ropa: Kuongorora ropa kunogona kuona maitiro akareba ekuita mabasa eumunological. Zvimwe zviratidzo zvekuwedzera kwemuviri wemuviri zvinosanganisira kukwirira kwemasero emuropa, eerythrocyte sedimentation rate (ESR), uye anti-nuclear antibody (ANA). Zvose izvi, zvisinei, zvinogona kuratidza hutachiona hwehutachiwana uye hutachiona hwemunofanzvi, naizvozvo hazvirevi kuti angioedema.
Dzimwe nguva, hapana mhirizhonga inozivikanwa uye angioedema inogona kuva kuongororwa kwekuregererwa mushure mechimwe chikonzero chezviratidzo zvakatongerwa kunze.
Hereditary Angioedema
Chiyero chekuberekwa uye kuongororwa ropa kunogona kuziva ichi. Zvinowanzova nyore kuti uve neropa rekuedzwa.
- Kuongorora Kuongorora: Kuongororwa kweropa kunotanidza mazinga eC4 angashandiswa sekuongorora kuongorora ropa kweropaedio. Kuderera kweC4 kunotaridza autoimmune disorder, uye uwandu hwepamusoro hunoratidza kuti unoda imwezve kuongororwa kweropa kuti uone kuti C1 inhibitor inoshaya. Kana pane chiitiko chakakura chokuti iwe unotora nhaka yengano, iwe unoda kutevera ropa rekutsvaga kweC1 inhibitor inoshaya. Asi kana iwe uine mukana wakaoma wekuti uwane angioedema inotora nhaka, C4 yakakwana inokurudzira kuti hauna mamiriro acho.
- Ropa Ropa: Kuongorora ropa kunoratidza chirema muC1 esterase inhibitor protein (C1-INH). Nhamba yeC1-INH inogona kunge yakaderera pane yakasarudzika, kana inogona kuva yakasununguka asi isiri kushanda. C1-INH ipuroteni inoshanda kuti urambe uine masimba ezvirwere mumuviri kuitira kuti irege kunyanyisa. Chiremera chemafu chinokonzerwa nemhando yerudzi I angioedema, izvo zvinoguma nemaitiro asina kukwana eC1-INH kana kuti chirongwa che ll angioedema, chinokonzera basa risina kujairika reC1-INH.
- Genetic Test: Izvozvo zvakasiyana-siyana zvinokonzera kuti angioedema iwanikwe pane SERPING1 geni yekutevedzera l uye ll angioedema. Kuchinja-famba pane F12 geni kunogona kuonekwa nechemi lll angioedema. Mhedzisiro chaiye yekusakanganiswa uku haisi kunzwisiswa zvakanaka.
Hereditary angioedema inotora nhaka kubva kuvabereki vane chiziviso chinotaridzika, izvo zvinoreva kuti kana munhu ane geni rechiitiko ichi, zviratidzo zvechirwere dzichakura. Nemhaka yekuti inoshandiswa pakuzvidzivirira, chero chero mubereki iwe unotora nhaka yegeni ye angioedema rudzi l, ll kana lll inofanirawo kunge ine zviratidzo zvechiitiko nokuti iyo ndiyo inonyanya kukoshesa. Hereditary angioedema haisi isiri, inongoda chete 1 mu 50 000 vanhu.
Kazhinji yenguva, angioedema inokonzerwa nemajeni aya akagara nhaka asi munhu anogona kukudziridza gene gene mutation pakarepo, zvinoreva kuti zvinobvira kukudziridza kuchinja kwehupenyu kunokonzera mamiriro acho asina kutora nhaka kubva kuvabereki vako.
Imaging
Kufungidzira hakuwanzobatsira pakuongorora angioedema. Mune mamwe mamiriro ezvinhu, kunyanya kana pane kupererwa kwepfufu kana kuti matambudziko emakumbo akadai sekushushikana kwemudumbu, kuora mwoyo, uye chirwere chinokonzera matambudziko, kuongororwa kwekufungidzirwa kwekufungidzira kutonga zvimwe zvirwere zvinogona kudiwa.
Kusiyanisa Kuziva
Kune mamwe maitiro mashomanana anogona kuita zviratidzo zvakafanana neaya angioedema.
Bata Dermatitis
Mamiriro ezvinhu akafanana neangioedema, kusangana dermatitis kunobva pakubatana nenhengo inobereka hypersensitivity. Mamiriro acho akafanana uye zvingave zvakaoma kutaura mutsauko. Kubata dermatitis hazvibatanidzi nekuputika, uye kunokonzera ganda rakanyanyisa, kubwinya, uye kuputika kana kuvhara ganda.
Edema Pamusana pehutachiwana kana kukuvadzwa
Edhiema kuzvikudza kwechikamu chipi nechipi chemuviri. Izvo zvinogona kuitika mukupindura kukuvara kana chirwere, pane izvozvi zvingaitika nokukurumidza uye pakarepo, zvakafanana neodema ye angioedema.
Kungofanana neangioedema, edema nekuda kwekukuvara kana tsukamu inogonawo kusanganisira nzvimbo iri yoga yemuviri. Pane kusiyana kwakanyanyisa pakati peedema, zvisinei, kusanganisira inogona kuita fevri uye kurwadziwa kwakanyanya kana chikonzero chacho chiri kukuvara kana utachiona.
Kusakanganiswa Kwemwoyo kana Kushaya Kutswa kweAyi
Iroema yemoyo yekukundikana kana kushaya kukanganisa kunowanzopera. Kazhinji nguva, edema haisi chiratidzo chokutanga chemamiriro aya.
Mamwe mashomanana anokosha akasiyana ndeokuti edema yemoyo kusagadzikana kana kuti kusaputsika kwepvo kazhinji kunowirirana, izvo zvisingafaniri kunge zviri mamiriro e angioedema. Iyo edema ye angioedema haisi pitting, nepo edema yemoyo kusagadzikana kana kushaya kwepfungwa kunokodzera edema.
Deep Vein Thrombosis (DVT)
DVT inokonzera kubhekwa kwechimwe chikamu chemuviri, kazhinji kacho gumbo rezasi. Kungofanana neangioedema, inogona kunge ichinge yaitika kamwe-kamwe, isingafadzi, uye isingaenzaniswi. DVT inogona kukonzera pulmonary embolism, zvichiita kuti kuporesa kunetseke. A DVT haitarisirwi kuendeswa nekuputika kwemiromo kana maziso.
Lymphedema
Kuvhara kwekuyerera kwemvura kunenge kuchiitika mumuviri kunogona kuitika nekuda kweropa rekudzivirira. Izvi zvinogona kuitika pashure pemamwe marudzi ekuvhiyiwa, kunyanya chirwere chekenza.
Mimwe mishonga inogona kubudisa lymphedema zvakare. Inowanzozivikanwa nekudzidzira mune imwe ruoko uye kazhinji haigone pasina nhoroondo yezvokurapa iyo inoratidza kuti lymphatic system inokonzera.
> Sources:
> Bova M, De Feo G, Parente R, et al. Hereditary and Acquired Angioedema: Heterogeneity yePathogenesis uye Clinical Phenotypes. Int Arch Allergy Immunol. 2018; 175 (3): 126-135. doi: 10.1159 / 000486312. Epub 2018 Jan 26.
> Kuperstock JE, Pritchard N, Horný M, Xiao CC, Brook CD, Platt M, Inhalant allergen sensitization ndeyezvipingamupinyi zvinokonzerwa nekugadzirwa kwe angioedema. Am J Otolaryngol. 2018 Mar-Apr; 39 (2): 111-115. doi: 10.1016 / j.music.2017.12.013. Epub 2017 Dec 27.