8 Zvinhu Zvinokudza Platelet Yenyu

Nenzira yakawanda, platelet yakawanda kupfuura 450,000 masero per microliter inofungidzirwa yakakwirira; izvi zvinonzi "thrombocytosis". Kune zvikonzero zvakawanda zveprombocytosis uye nerufaro, ruzhinji rune simba uye runopera. Regai tiongorore zvimwe zvikonzero zvinowanzoitika.

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Myleoproliferative Disorders

Matambudziko anokonzerwa ne myleoproliferative (chirwere apo bone marrow anoita masero akawanda eropa) anogona kukonzera thrombocytosis. Izvi zvinosanganisira polycythemia vera , inonzi thrombocythemia (ET) inokosha, uye myelofibrosis inokosha.

Mune ET, somuenzaniso, marora emapfupa anoita megakaryocytes yakawanda, masero anoita maplatelet, zvichiita kuti thrombocytosis iite. Nezviitiko izvi, nhamba dzakawandisa dzemaplatelets anoita kuti ropa rive rakakura uye riyerere zvishoma nezvishoma izvo zvingaita kuti ropa rivhare. Mishonga inotarirwa kuderedza platelet count kuti kuderedze njodzi iyi.

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Kurwara

Muvana nevakuru, zvirwere zvinokonzera chikonzero chikuru cheplatelet count. Uku kukwirira kunogona kunge kwakanyanya, uye platelet inopfuura mamiriyoni emasero masero ne microliter.

Ruzhinji rwevanhu vanoona izvi izvi hazvirevi asi boka duku revarwere vane dzimwe ngozi zvinogona kuwedzera ropa. Platelet inowanzodzoka kune yakashure mushure mekugadzirisa kwehutachiona, asi izvi zvinogona kutora vhiki dzinoverengeka. Mune vamwe varwere, thrombocytosis inogona kunge ichingokuvadza mushure mekunge iine thrombocytopenia (pasiplate yakadzika) panguva yekutachiona kwekutanga.

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Kushayiwa Kwemidhi Anemia

Kunyange zvazvo hemoglobin yakaderera uye masero masero matsvuku eropa ndiyo iyo inowanzo ma laboratory maitiro anosanganiswa nehutachiona hwehutera anemia, kukwirira kweplatelet count haisi isiri. Panguva ino, hazvizivikanwe kuti chii chinokonzera izvi thrombocytosis. Muzhinji, zvinosungirirwa zvakanaka uye zvinogadzirisa neyakakodzera yesimbi yekuwedzera mishonga.

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Kusina Spleen

Chimwe cheplatelet inogara mu spleen yedu chero nguva ipi zvayo. Kana chirwere chacho chichibviswa chirwere (splenectomy) kana kuti chichirega kushanda zvakanaka (functional asplenia) sechirwere chetachiona chirwere, thrombocytosis mhinduro. Iyi thrombocytosis inowanzova yenyoro kusvika pakuenzanisa uye yakarerukirwa.

Pakarepo mushure mekunge splenectomy, iyo thrombocytosis inogona kuva yakaoma uye inogona kuita kuti kuve neropa. Iyi post-splenectomy complication inoitika inenge 5 muzana yevarwere. Nenzira yakawanda, dambudziko iri rakakura mumwedzi mushure me splenectomy.

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Inflammatory Conditions

Mamiriro ezvinhu nekuputika kwakafanana nerheumatologic disorders, chirwere chinoputira chiropa, uye vasculitides zvinogona kuva ne-thrombocytosis. Iyo yakakwirira yeplatelet inowanikwa mukupindura ma cytokines (maduku emaprotini akabudiswa kubva mumasero anoratidza mamwe masero kuti aite chimwe chinhu). Kunyanya, iyo cytokines interleukin-6 uye thrombopoietin inokurudzira platelet yekugadzira.

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Mixed Cryoglobulinemia

Mixed cryoglobulinemia inogona kukonzera kukwirira kwenhema mu platelet count. Mune chiitiko ichi, cryoglobulins (mapuroteni) muropa anonamatira pamwe chete paanotaridzirwa kutonhora kunotonhora (kufanana nemaoko nemakumbo). Izvi zvikamu zvinogona kunge zvisiri zvenhema zvinonzi seplatelet nemushandi unoita ropa rose rakawanda . Izvi zvinosanganiswa nehutachiona hweH hepatitis C, systemic lupus erythematosus, uye rheumatoid arthritis.

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Hemolytic Anemia

Kana hemolytic anemia (anemia yechipiri kusvika kune tsvuku tsvuku yeropa) inoguma mukuumbwa kwemasero matsvuku eropa, aya masero matsvuku eropa angave asina kuverengwa seaplatelets nemushandi unoita kuwandisa kwekuzara kweropa. Izvi zvinogona kuongororwa kuburikidza nekuongororai imwe yeropa ropa smear (microscope slide yeropa). Nhamba yakaonekwa yemaplatelet ichave yakaderera nematare mashoma masero eropa anoonekwa.

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Malignancy

Thrombocytosis inogona kuva yechirwere chechipiri chezvimwe zvirwere (kanzira). Izvi zvinonzi separaneoplastic thrombocytosis. Izvi zvinowanzosangana mumakumbo akaoma semukenza wemapapu, hepatocellular (chiropa) carcinoma, kenza yemaawa, uye kanzira inorwara. Yakawandisa platelet count inogonawo kuonekwa mune zvisingaperi zvinokonzerwa neukemia (CML) .