Xolair (omalizumab) yakaratidzwa kuti inoderedza kuwandisa kwekurwiswa kwechirwere muhuwandu kusvika kuhutachiwana hwechirwere, uye kuderedza kana kubvisa kudiwa kweimwe mishonga yekurapa .
Ndichabatsirwa neColaola?
Vamwe varwere vane chirwere chinonzi allergic asthma vanoita zvakanyanya IgE izvo zvinogona kukonzera kuwedzera kwezviratidzo zvechirwere zvakadai sokuti:
Pakati pese, unogona kubatsirwa kubva kuXolair kana uine:
- Yakapfuurira yakasimba kana yakasimba yakaramba ichiita
- Kunzwisisika kune anoregen uye chirwere chisina kujairika chirwere seRAST
- Haana kuwana mhinduro yakanaka kune steroid inoputika se Flovent kana steroid inoputika pamwe chete nemakore akawanda ari kuita beta agonist seAdvair .
Uyezve, vamwe varwere vane chirwere chebasa vanoita basa vasingakwanisi kugadzirisa nzvimbo yavo yebasa vanogona kubatsirwa nekurapwa naXolair. Vamwe vatsigiri veAetna vanoda zvimwe zviyero zvinosangana vasati vabvuma kubhadharwa kweXolair pakutanga uye kuti inoramba ichishandiswa.
Chinoshanda sei?
Xolair inoshanda pane dzakawanda dzakasiyana dzakasiyana maererano nehupmma pathophysiology inosanganisira:
- IgE
- Mast cells
- Basophils
Kuburikidza nekuita kwayo, mizinga yeGE inopera pamwe chete nebasa reasophils uye mast cells. Chigumisiro chacho chichidzikira kuputika uye kuendesa kune airway hyperresponsiveness zvichikonzera kuvandudzwa kwekliniki yakambotaurwa kare.
Ndiani Angatora Xolair?
Iwe unogona kushandisa Xolair kana iwe uri nemakore gumi nemaviri nemakore.
Xolair Inotungamirirwa Sei?
Your Xolair (omalizumab) dose yakabva pane yako:
- Weight
- IgE level
Zvichienderana nehutoro hwako uye IgE level, uchawana ganda remukati (pasi peganda) mavhiki maviri nemashanu. Unofanirwa kugamuchira majekisi kwemasvondo gumi nemaviri kuti uone kana Xolair inoshanda kwauri.
Kana uchida kumisa Xolair nekuda kwemigumisiro kana chimwe chikonzero, mishonga yekurapa inotanga kupfeka uye ichazoenda zvachose mumwedzi mitanhatu. Hakuchina zvigaro zvekusingaperi zvekugamuchira majekiseni.
Nemhaka yehutachiwana hwevanaphylaxis, uchawana majekiseni eXolair muhofisi yechiremba wako uye uchafanira kugara kwemaawa maviri kuti uone kuti hauna kutanga kuita. Chiremba wako anogonawo kukupa uye kukudzidzisa pamusoro peEpiPen kana epinephrine injector kuti ushandise kana iwe ukatanga zviratidzo zvevanaphylaxis kunze kwehofisi.
Migumisiro yakaipa
Mune zvidzidzo zvekuchipatara kuwana Xolair inogamuchirwa neDFA, inoita seyo yakachengeteka. Xolair yakapiwa kune vanhu vanopfuura 2000 nevechiri kuyaruka vanopfuura makore gumi nemaviri. Kubva munaJanuary 2010, izvi zvaisanganisira varwere vanopfuura 1600 vanorwara neAxolair kwemwedzi inopfuura 6 uye vanopfuura 550 varwere vachishandisa Xolair kwegore kana kupfuura.
Migumisiro yakaipa inowanzoitika yakaitika inenge yakafanana kune vose vari kutora Xolair nevaya vanotora placebo. Kunewo huwandu hwehuipi hunogona kukuvadza hunoti munhu anofanira kunge achiziva zvose asati atanga kurapwa na Xolair uye kuti uzviongorore zvakasimba neavo vanoita zvekuchengeta asthma.
Nenzira yakanaka, zvinokonzera kukanganisa zvinokonzera kuitika kune zvisingasviki 1% zvevarwere vanobatwa ne Xolair.
Nyaya yekuchengeteka yeXolair inosanganisira iyo inogona kunge yakakosha Inyevero yeBhokisi inobatana nevanaphylaxis uye imwe nyevero inobatana nekenza .
Isina Xolair Yakachengeteka here?
Varwere vazhinji vanowanzobvunza mibvunzo pamusoro pekuti mushonga unenge wakachengeteka kana kwete. Sezvo mishonga yose ine migumisiro yakaipisisa, mubvunzo uyu unonyatsopisa kuti iwe uye chiremba wako munofunge kuti zvingava nemigumisiro yei Xolair yakakura kana kuti isiri kudarika zvingave zvingakubatsira. Iwe uye chiremba wako unofanira kunge uine hurukuro kurukura nezvezvipingamupinyi uye zvibatsiro usati waita chisarudzo.
Zvinowedzera Zvakadii?
Xolair inodhura zvikuru, kubva pa $ 500 kusvika ku $ 2000 pamwedzi. Taura nachiremba wako pamusoro pekuwana inshuwarisi yekuwana kurapwa uku.
Sources:
Xolair Web Site. Xolair Kunyora Mashoko
Barnes PJ. Anti IgE Therapy. www.UpToDate.com