West Syndrome

West Syndrome uye Infantile Spasms

West syndrome inzira yekutora chirwere (epilepsy) inotanga mucheche. Mhando yakananga yokutora inonzi infantile spasm chikamu chechirwere ichi, sezvinenge zvisingawanzoitiki zvepfungwa dzemapurogiramu anonzi hypsarrhythmia, uye kuchera kwepfungwa. Anenge chero mamiriro ezvinhu anogona kukonzera uropi hunoita kuti West syndrome iite. Izvozvo zviviri zvinowanzokonzera ndeye tuberous sclerosis uye kushaya oxygen panguva yekuzvarwa.

Dzimwe nguva chinokanganisa chinongopomerwa asi hachigoni kusimbiswa; munyaya iyi, inonzi "cryptogenic West syndrome."

West syndrome inokonzera 2 muzana yemapupa muhuduku, asi 25 muzana yekufa kweputika inotanga mugore rokutanga rehupenyu. Chiyero chep inflele spasm inofungidzirwa pakati pe2,5 kusvika ku6.0 kusvika kune 10 000 kuberekwa patsva.

Zviratidzo zveWest Syndrome

West syndrome inowanzotanga pakati pemakore 3-6 kwemwedzi.Symptoms dzinosanganisira:

• Infantile spasms - Kazhinji kacho mumhando iyi yekubata mwana anononoka achienda mberi pachiuno uye muviri, maoko, uye makumbo zvinomesa. Izvi dzimwe nguva zvinonzi "jackknife" seizure. Vamwe vana vanogona kupfutira misana yavo, kana kuvhudza misoro yavo, kana kuti kuyambuka maoko avo kumativi ose semuviri sezvavari kuzvikumbira. Izvi zvinopedza mashomanana mashomanana uye zvinowanikwa mumasumbu emunharaunda kubva kune 2 kusvika ku100 mapasita panguva imwe. Vamwe vana vane mazana mashoma emasumbu aya emazuva mashoma. Masaisai anowanzoitika mushure mechecheche anomuka mangwanani kana kuti apera.

• Hypsarrhythmia - An electroencephalogram (EEG) inorondedzera mabasa emagetsi muuropi nenzira yemafungu europi. Mucheche ane West West ane chirwere chisina kujairika, chaotic brain wave patterns dzinonzi hypsarrhythmia.
• Kuora mwoyo kwepfungwa - izvi zvinokonzerwa nekukuvara kwepfungwa kwakakonzera West syndrome.

Zvimwe zviratidzo zvinogona kunge zviripo nekuda kwechirwere chepfungwa chinokonzera West syndrome.

Zvimwe zvinetso zvehupfungwa zvehutano zvakadai sa cerebral palsy zvinogona kuvapo zvakare.

Kuongorora West Syndrome

West syndrome icharatidzwa nekuvapo kwevana vaduku. Chidzidzo chepfungwa chepfungwa chepamusoro chichaitwa kuitira kutarisa zvinokonzera zvinokonzera. Izvi zvinogona kusanganisira kuongorora ma laboratory uye kuongorora kweuropi uchishandisa computed tomography (CT) kana magnetic resonance imaging (MRI). EEG ichaitwa kutarisa hypsarrhythmia kazhinji inowanikwa muWest syndrome.

Kurapa kweWest Syndrome

Kazhinji kacho West West syndrome inorapwa neAdrenocorticotropic hormone (ACTH) kana prednisone. Izvi zvinogona kunge zvichinyatsobudirira pakurambidza kana kuderedza zviduku zvishoma. Vamwe vacheche vanogona kupindura mishonga inosvibisa seFelbatol (felbamate), Lamictal (lamotrigine), Topamax (topiramate), kana Depakote (valproic acid). Vacheche vane tuberous sclerosis vanogona kurapwa ne vigabatrin (kwete ikozvino yakagamuchirwa kuti ishandiswe muUnited States). Dzimwe nguva, kubviswa kwehutachiona hunokanganisa kuburikidza nekuvhiyiwa kweuropi kunogona kubudirira.

Infantile spasms inowanzogadzirisa neanenge makore mashanu, asi inopfuura hafu yevana vanobatwa ichawedzera mamwe maitiro ekugumburwa, kusanganisira Lennox-Gastaut syndrome. Vacheche vakawanda vane West syndrome vane nguva refu yekuziva uye kudzidzira kuora mwoyo, zvichida nekuda kwekukuvara kweuropi izvo zvakakonzera kusununguka kwevana.

> Sources:

_{"NINDS Infantile Spasms Information Page." Matambudziko AZ. 9 Dec 2008. National Institute of Neurological Disorders uye Stroke.}

_{"Infantile Spasms / West Syndrome." Epilepsy Syndromes. Epilepsy Foundation.}