Vitamin Defence and Migration Neurological
Vitamin kukanganisa kunogona kukonzera matambudziko akasiyana-siyana ehutano. Chimwe chezvinhu zvinotyisa ndeye myeloneuropathy, zvinoreva zvinetso nemutsipa wepelinha uye purogiramu yenheyo yenheyo .
Matambudziko ehutano nehutano hwakakonzerwa nehutachiona hwehutachiona hwakatanga kuonekwa munenge muna 2004. Vanhu vanotanga kuve neatayia nechisimba nekuda kwekushaikwa kwekugona kutaura kuti zvikamu zvemuviri wavo zvakange zvakadini munzvimbo.
Unhu nehutera zvakagadzirwa zvakare. Pamusoro pekuongororwa kwepfungwa, mafungiro akawanika kunge asina kukanganisa.
Chimwe chezvinhu zvinonyanya kuzivikanwa zveyelononeuropathy ndiyo inokonzerwa neApps vitamin B12. Asi mamwe mavitamini akanganisa semhangura, folate , kana vitamini E anogonawo kukonzera matambudziko nemutsipa wepelinha.
Vitamini B12 Kukwana
B12 kushayikwa kunogona kukonzera nhamba yakawanda yematambudziko akasiyana-siyana emagetsi, asi inonyanya kuzivikanwa ndeyangu myeloneuropathy inonzi subacute yakabatana nokusagadzikana . B12 inoshaya inokonzera zvirwere zvemashure ekupedzisira emutsara wepelinha, iyo inotakura mashoko pamusoro pekugunzva, chiedza uye chimiro chemuviri munharaunda (kuwanikwa) kubva mumuviri kuenda kune uropi. Somugumisiro weiyi myeloneuropathy, kupera uye kushaya simba chikonzero. Izvo zvinoshaya zvinowanikwa mu "pattern-stocking-glove pattern" iyo inoreva kuti inofamba zvishoma nezvishoma uye yakasimudza maoko nemakumbo (mushure mokutanga mumakumbo nemaoko).
Kushayikwa Kwemhangura
Kushayikwa kwemhangura kwakafanana neyekushaya B12. Chikonzero chinonyanya kukosha ndeye malabsorption, yakadai seye mushure mekuvhiyiwa kwainzi bariatric, kana malabsorption syndromes sehosha yeeceliac . Kuwedzerwa kwezinc kuwedzerwa kunogona kutungamirirawo kushayikwa kwemhangura. Mukuwedzera kune zinc inowedzera, mamwe mazinyo ekisi anewo zvakanyanya mazinga e zinc.
Kuonekwa kwekushaiwa kwemhangura kunogona kuitwa nekuongororwa kwemaketani muropa - uye kazhinji, chiremba achaongorora zinc uyewo.
Mushonga wekushaiwa kwemhangura ndeyekuwedzera nemuromo wemhangura uye, kana zvichidiwa, kuderedza zinc kushandiswa.
Kushayikwa Kwechirwere
Huru (tetrahydroflic acid) inowanikwa mumuchero wevirirusi nemiriwo miriwo mashizha. Inogona kuva yakaderera mudhakwa kana malabsorptive syndromes. Pakubata pamuviri, madhigirii akaderera anogona kutungamirira kumusana wechipfuva chisina kunaka, izvo zvaita kuti zvikurudziro zvekuti vakadzi vanowedzera ne vitamini iyi kana vari kufunga nezvekuita pamuviri.
Kushayikwa kwechirwere kunowanzosangana nemamwe mavitamini anoshaya izvo zvinogona kukonzera maitiro emagetsi. Izvo zvakati, maitiro akafanana nekutarisana kwekugadzirisa kusanganiswa akave akarondedzerwa nehuwandu hwema folate, nechinangwa chekuziva, uyewo kushaya simba uye kushaya simba, uye vanachiremba vachiri kutsvaga nhengo yeropa muropa kana zviratidzo izvi zviripo uye zvinoreva myeloneuropathy.
Folic acid inotorwa nyore nyore nemuromo asi inogonawo kuvhara kushayikwa kwevhitamiti B12 uye inowedzera kuipa kwemaeloneuropathy yomunhu. Ichi ndicho chiremba vanachiremba vachabvisa hutachiona hweBvatin B12 vasati vatanga folic acid supplementation.
Vitamin E Kukwana
Kunyange zvazvo chirwere chepfungwa chinonyanya kukanganiswa mu vitamine E chikafu chinonzi spinocerebellar syndrome, kazhinji kacho kunowanzobatanidza fiber huru-inonyanya kukonzerwa nexonal peripheral neuropathy. Vitamin E inoshaya inowanikwa munzvimbo yakaoma mafuta malabsorption (p., Biliary kusagadzikana, cystic fibrosis) kana zvirwere zvepabonde (semuenzaniso, ataxia ine vitamin E inopera kana abetalipoproteinemia). Nzira dzekurapa kushayikwa kwevhitamin E dzinosanganisira kuvandudza mafuta ekugadzira uye muromo wemavhithamini E supplementation.
Vitamini E is vitamini yakasviba yakawanikwa mumbeu, mbeu, uye gorosi germ. Hazviwanzovi kuti kushayikwa kwevitamini E kunokonzerwa nokushaya kukwana kwezvokudya, asi kunogona kuguma kubva mumamiriro ezvinhu anokonzera mafuta akawanda marabiorption.
Kugadzikana kwakakwana kwevhitamine E kunoda mapenicreatic enzymes uye bile salts kubva pachiropa. Dzimwe nguva kune zvakagadzirirwa nhaka ye vitamini E metabolism inogona kukonzera zvinetso, kunyanya muvana.
Zviratidzo zvekushaiwa kwevhitamine E zvinosanganisira kufamba kwemaziso kusina kuipa, kuonekwa kwemaonero, cerebellar ataxia uye chirwere chepfungwa chinokonzerwa neuropathy, kuwedzera pane zviratidzo zvepamusoro pakakoromora kurasikirwa kwepfungwa nenzira inoyeuchidza zvimwe hutachiona husina kunaka hukurukurwa.
Vitamin E mazinga anokwanisa kuenzaniswa zvakananga muropa, kunyange mazinga aya anogona kuchinjwa nemazinga echolesterol uye lipids muropa. Kurapa kwehutachiona hweVitamin E kune muromo wevitamine E kunowedzera nekuvandudza kufunganya kwemafuta (kurapa mamiriro ekurapa, kana zvichibvira).
Pasi Pasi
Kunyange zvazvo myeloneuropathy inokonzerwa nokushayikwa kwevhitamini iyi inogona kuva yakaoma, mashoko akanaka zviratidzo zvinogona kuvandudza kana kutombomira nekurapa kwakakodzera.
Kana chiremba wako achikuedza kuti uwane myeloneuropathy, anokwanisa kuronga magnetic resonance imaging (MRI), iyo inogona kuratidza zvipembenene mumashure ekupedzisira emutsipa wepelinha uye electromyogram (EMG) uye nhungurudzo yekudzidza nerve (NCS) , inoratidza kuramba .
Sources:
Brent, P. Goodman, Chirongwa chekuona Maeloneuropathy; Continuum: Mutsara wemutsipa, Muto, uye Plexus Zvinetso Mubhuku 17, Nhamba 4, August 2011.
O, RC, & Brown, DL (2003). Vitamini B12 Kukwana. American Family Physician , Mar 1; 67 (5): 979-86.
Ropper, AH Samuels, MA Adams uye Victor's Principles of Neurology, 9th ed: The McGraw-Hill Companies, Inc., 2009.
Vashandi, NP & Windebank, AJ (2014). Purogiramu yeuropathy inokonzerwa nevitamini, urombo, uye mishonga. Continuum (Minneap Minn) , Oct; 20 (5 Peripheral Nervous System Disorders): 1293-1306.
ZVINOKUDZIDZA: Mashoko ari panzvimbo ino ndeongangwa dzekudzidzisa chete. Icho hachifaniri kushandiswa sechinzvimbo chekuchengetedza iwe pachako nechiremba ane chiremba. Ndapota ona chiremba wako kuti aongororwe uye kurapwa chero kupi zvako pamusoro pezviratidzo kana chirwere chechiremba .